Patents by Inventor Kevin ESVELT

Kevin ESVELT has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ROBOTIC SYSTEMS AND METHODS FOR AUTONOMOUS DIRECTED EVOLUTION OF HORIZONTALLY TRANSFERRED NUCLEIC ACIDS
    Publication number: 20190345487
    Abstract: The invention, in part, includes systems for conducting continuous directed evolution in a plurality of sample and methods of using the systems. The invention, in part also provides systems for evaluating the suitability of diverse engineered cells to accomplish directed evolution and methods of use of such systems.
    Type: Application
    Filed: May 7, 2019
    Publication date: November 14, 2019
    Inventors: Kevin Esvelt, Erika Alden DeBenedictis
  • METHODS AND COMPOUNDS FOR GENE INSERTION INTO REPEATED CHROMOSOME REGIONS FOR MULTI-LOCUS ASSORTMENT AND DAISYFIELD DRIVES
    Publication number: 20190241879
    Abstract: The invention relates, in part, to methods to design and construct gene drives such as daisy chain gene drives, suppression gene drives, and other types of gene drives that may be included in cell lines and organisms.
    Type: Application
    Filed: September 9, 2017
    Publication date: August 8, 2019
    Applicants: Massachusetts Institute of Technology, President and Fellows of Harvard College
    Inventors: Kevin ESVELT, Jianghong MIN, Charleston NOBLE
  • METHODS AND COMPOSITIONS FOR IN VIVO TRANSGENESIS
    Publication number: 20190194610
    Abstract: The invention relates, in part, to methods to deliver molecules into in vitro and in vivo cells and into organisms using exogenous and/or endogenous membrane proteins.
    Type: Application
    Filed: November 2, 2018
    Publication date: June 27, 2019
    Inventor: Kevin Esvelt
  • Orthogonal Cas9 proteins for RNA-guided gene regulation and editing
    Patent number: 9587252
    Abstract: Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: March 7, 2017
    Assignee: President and Fellows of Harvard College
    Inventors: George M. Church, Kevin Esvelt, Prashant Mali
  • Orthogonal Cas9 Proteins for RNA-Guided Gene Regulation and Editing
    Publication number: 20150259684
    Abstract: Methods of modulating expression of a target nucleic acid in a cell are provided including use of multiple orthogonal Cas9 proteins to simultaneously and independently regulate corresponding genes or simultaneously and independently edit corresponding genes.
    Type: Application
    Filed: March 31, 2015
    Publication date: September 17, 2015
    Inventors: George M. CHURCH, Kevin ESVELT, Prashant MALI