Abstract: A method of delivering a multi-phase fluid injection to a patient via a fluid injector comprising two or more syringes includes injecting a first fluid of the fluid injection from at least a first syringe at a first predetermined flow rate, wherein the first fluid has a first viscosity; injecting an initial portion of a second fluid from at least a second syringe at an intermediate flow rate different than a second predetermined flow rate for a specified time, the second fluid having a second viscosity different from the first viscosity; and injecting a remaining portion of the second fluid of the fluid injection at a flow rate at the second predetermined flow rate. A fluid injector system configured for delivering a multi-phase fluid injection is disclosed.