Patents by Inventor Kevin Friedman

Kevin Friedman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for manufacturing adoptive cell therapies
    Patent number: 12291722
    Abstract: The invention provides compositions and methods for manufacturing adoptive cell therapies. In particular embodiments, the invention provides methods of harvesting populations of cells, isolating and activating PBMCs, expanding T cells, and administering the T cell therapeutic to a subject in need thereof.
    Type: Grant
    Filed: April 24, 2015
    Date of Patent: May 6, 2025
    Assignee: 2seventy bio, Inc.
    Inventors: Richard Morgan, Kevin Friedman, Dawn Maier
  • Anti-BCMA CAR antibodies, conjugates, and methods of use
    Patent number: 12247084
    Abstract: The invention provides improved methods for detecting anti-BCMA CAR expression on T cells.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 11, 2025
    Assignee: 2seventy bio, Inc.
    Inventors: Kevin Friedman, Molly Reed Perkins
  • CD79A CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20250026828
    Abstract: The invention provides improved compositions for adoptive cell therapies for cancers that express CD79A.
    Type: Application
    Filed: June 27, 2024
    Publication date: January 23, 2025
    Inventors: Kevin Friedman, Molly Reed Perkins
  • BCMA CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20250026845
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Application
    Filed: June 7, 2024
    Publication date: January 23, 2025
    Inventors: Richard Morgan, Kevin Friedman
  • BCMA CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20240417481
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Application
    Filed: May 15, 2024
    Publication date: December 19, 2024
    Inventors: Richard Morgan, Kevin Friedman
  • MND PROMOTER CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20240401080
    Abstract: The invention provides vector compositions for delivering improved adoptive T cell therapies.
    Type: Application
    Filed: June 5, 2024
    Publication date: December 5, 2024
    Inventors: Richard Morgan, Kevin Friedman, Byoung Ryu
  • CD79A chimeric antigen receptors
    Patent number: 12060419
    Abstract: The invention provides improved compositions for adoptive cell therapies for cancers that express CD79A.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: August 13, 2024
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Kevin Friedman, Molly Reed Perkins
  • BCMA chimeric antigen receptors
    Patent number: 12029784
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: July 9, 2024
    Assignee: 2seventy bio, Inc.
    Inventors: Richard Morgan, Kevin Friedman
  • BCMA chimeric antigen receptors
    Patent number: 12006369
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: June 11, 2024
    Assignee: 2seventy bio, Inc.
    Inventors: Richard Morgan, Kevin Friedman
  • SURGICAL RETENTION FEATURE
    Publication number: 20230380925
    Abstract: A light guide assembly for use with a retractor having a channel for slidably receiving an end portion of a light guide. The light guide assembly includes a light guide having the end portion for slidably inserting into the channel and retentor for releasably holding in position the end portion relative to the retractor.
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Applicant: Lumitex Inc.
    Inventors: Brandon Shafer-Zatko, RJ Hagler, Joe Dombrowski, Kevin Friedman, Vedang Kothari, Brian Andrich, Alan Greszler
  • Surgical retention feature
    Patent number: 11759282
    Abstract: A light guide assembly for use with a retractor having a channel for slidably receiving an end portion of a light guide. The light guide assembly includes a light guide having the end portion for slidably inserting into the channel and retentor for releasably holding in position the end portion relative to the retractor.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: September 19, 2023
    Assignee: Lumitex Inc.
    Inventors: Brandon Shafer-Zatko, R J Hagler, Joe Dombrowski, Kevin Friedman, Vedang Kothari, Brian Andrich, Alan Greszler
  • METHODS FOR MAKING T CELL COMPOSITIONS
    Publication number: 20230193202
    Abstract: The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.
    Type: Application
    Filed: December 20, 2022
    Publication date: June 22, 2023
    Applicant: 2seventy bio, Inc.
    Inventor: Kevin FRIEDMAN
  • BCMA chimeric antigen receptors
    Patent number: 11633463
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Grant
    Filed: April 1, 2020
    Date of Patent: April 25, 2023
    Assignee: 2seventy bio, Inc.
    Inventors: Richard Morgan, Kevin Friedman
  • ANTI-BCMA CAR ANTIBODIES, CONJUGATES, AND METHODS OF USE
    Publication number: 20230030085
    Abstract: The invention provides improved methods for detecting anti-BCMA CAR expression on T cells. The invention generally provides antibodies and antigen binding fragments thereof, conjugates thereof, and methods of using the same to detect, determine, or measure CAR T cells and/or CAR expression on one or more T cells.
    Type: Application
    Filed: December 16, 2020
    Publication date: February 2, 2023
    Applicant: 2seventy bio, Inc.
    Inventors: KEVIN FRIEDMAN, MOLLY REED PERKINS
  • Methods of making T cell compositions
    Patent number: 11560547
    Abstract: The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.
    Type: Grant
    Filed: October 9, 2019
    Date of Patent: January 24, 2023
    Assignee: 2seventy bio, Inc.
    Inventor: Kevin Friedman
  • T cell compositions
    Patent number: 11479755
    Abstract: The invention provides improved T cell compositions and methods for manufacturing T cells. More particularly, the invention provides methods of T cell manufacturing that result in adoptive T cell immunotherapies with improved survival, expansion, and persistence in vivo.
    Type: Grant
    Filed: December 7, 2015
    Date of Patent: October 25, 2022
    Assignee: 2seventy bio, Inc.
    Inventor: Kevin Friedman
  • COMPOSITIONS AND METHODS FOR TREATING CANCER
    Publication number: 20220280567
    Abstract: The invention provides improved compositions for adoptive cell therapies for cancers that express CD79A and/or CD20.
    Type: Application
    Filed: June 11, 2020
    Publication date: September 8, 2022
    Applicant: 2seventy bio, Inc.
    Inventor: KEVIN FRIEDMAN
  • CD79B CHIMERIC ANTIGEN RECEPTORS
    Publication number: 20220226374
    Abstract: The invention provides improved compositions for adoptive cell therapies for cancers that express CD79B. The present invention relates to improved compositions and methods for treating cancer. More particularly, the invention relates to improved anti-CD79B chimeric antigen receptors (CARs), genetically modified immune effector cells, and use of these compositions to effectively treat CD79B expressing cancers.
    Type: Application
    Filed: June 14, 2019
    Publication date: July 21, 2022
    Applicant: 2seventy bio, Inc
    Inventors: Kevin FRIEDMAN, Molly Reed PERKINS
  • BCMA chimeric antigen receptors
    Patent number: 11382965
    Abstract: The invention provides improved compositions for adoptive T cell therapies for B cell related conditions.
    Type: Grant
    Filed: October 23, 2020
    Date of Patent: July 12, 2022
    Assignee: 2seventy bio, Inc.
    Inventors: Richard Morgan, Kevin Friedman
  • MANUFACTURING ANTI-BCMA CAR T CELLS
    Publication number: 20220195060
    Abstract: The invention provides improved anti-BCMA CAR T cell compositions and methods for manufacturing anti-BCMA CAR T cell therapies. More particularly, the invention relates to improved methods of for manufacturing anti-BCMA CAR T cells that result in more potent, persistence, and efficacious adoptive T cell immunotherapies. In certain embodiments, the cells were manufactured from a subject that has a multiple myeloma or a lymphoma.
    Type: Application
    Filed: April 2, 2020
    Publication date: June 23, 2022
    Applicant: 2seventy bio, Inc.
    Inventors: Kevin FRIEDMAN, Eric Scott ALONZO