Patents by Inventor Kevin Gunderson

Kevin Gunderson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10319396
    Abstract: A plurality of transducer bars may be concurrently translated from a first orientation to a second orientation by a translation system that has first and second plates. The first plate can have a plurality of first notches with each first notch shaped to hold a transducer bar in a horizontal orientation. The second plate can have a plurality of second notches with each second notch shaped to translate the transducer bar from the horizontal orientation to a vertical orientation.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: June 11, 2019
    Assignee: Seagate Technology LLC
    Inventors: Glenn Johnson, Kevin Mayer, Peter Gunderson
  • Publication number: 20190145982
    Abstract: A method for analyzing macromolecules, including peptides, polypeptides, and proteins, employing nucleic acid encoding is disclosed.
    Type: Application
    Filed: May 2, 2017
    Publication date: May 16, 2019
    Applicant: Encodia, Inc.
    Inventors: Mark CHEE, Kevin GUNDERSON, Michael Phillip WEINER
  • Publication number: 20190085389
    Abstract: A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.
    Type: Application
    Filed: August 20, 2018
    Publication date: March 21, 2019
    Applicant: Illumina, Inc.
    Inventors: Robert C. Kain, David L. Heiner, Chanfeng Zhao, Kevin Gunderson
  • Publication number: 20180320225
    Abstract: This invention provides methods of amplifying genomic DNA to obtain an amplified representative population of genome fragments. Methods are further provided for obtaining amplified genomic DNA representations of a desired complexity. The invention further provides methods for simultaneously detecting large numbers of typable loci for an amplified representative population of genome fragments. Accordingly the methods can be used to genotype individuals on a genome-wide scale.
    Type: Application
    Filed: November 17, 2017
    Publication date: November 8, 2018
    Inventors: Kevin Gunderson, Frank Steemers
  • Patent number: 10053730
    Abstract: A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: August 21, 2018
    Assignee: ILLUMINA, INC.
    Inventors: Robert C. Kain, David L. Heiner, Chanfeng Zhao, Kevin Gunderson
  • Patent number: 9879312
    Abstract: Methods for the selective enrichment of nucleic acids.
    Type: Grant
    Filed: May 10, 2016
    Date of Patent: January 30, 2018
    Assignee: ILLUMINA, INC.
    Inventors: Frank J. Steemers, Kevin Gunderson, Kerri York, Melissa Shults Won
  • Patent number: 9797012
    Abstract: A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.
    Type: Grant
    Filed: November 12, 2014
    Date of Patent: October 24, 2017
    Assignee: ILLUMINA, INC.
    Inventors: Robert C. Kain, David L. Heiner, Chanfeng Zhao, Kevin Gunderson
  • Patent number: 9758816
    Abstract: A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.
    Type: Grant
    Filed: October 9, 2015
    Date of Patent: September 12, 2017
    Assignee: Illumina, Inc.
    Inventors: Min-Jui Richard Shen, Jonathan Mark Boutell, Kathryn M. Stephens, Mostafa Ronaghi, Kevin Gunderson, Bala Murali Venkatesan, M. Shane Bowen, Kandaswamy Vijayan
  • Patent number: 9598453
    Abstract: Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.
    Type: Grant
    Filed: May 20, 2015
    Date of Patent: March 21, 2017
    Assignee: ILLUMINA, INC.
    Inventors: Frank J. Steemers, Kevin Gunderson, Kerri York, Ryan Christopher Smith
  • Publication number: 20170051340
    Abstract: The present invention is directed to methods and compositions for the use of microsphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays.
    Type: Application
    Filed: August 31, 2016
    Publication date: February 23, 2017
    Inventors: Kevin Gunderson, John R. Stuelpnagel, Mark S. Chee, Jian-Bing Fan
  • Publication number: 20160289742
    Abstract: Methods for the selective enrichment of nucleic acids.
    Type: Application
    Filed: May 10, 2016
    Publication date: October 6, 2016
    Inventors: Frank J. Steemers, Kevin Gunderson, Kerri York, Melissa D. Shults
  • Patent number: 9441267
    Abstract: The present invention is directed to methods and compositions for the use of micro sphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays.
    Type: Grant
    Filed: July 2, 2014
    Date of Patent: September 13, 2016
    Assignee: ILLUMINA, INC.
    Inventors: Kevin Gunderson, John R. Stuelpnagel, Mark S. Chee, Jian-Bing Fan
  • Patent number: 9365897
    Abstract: Methods for the selective enrichment of nucleic acids.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: June 14, 2016
    Assignee: Illumina, Inc.
    Inventors: Frank J. Steemers, Kevin Gunderson, Kerri York, Melissa D. Shults
  • Patent number: 9289766
    Abstract: The invention relates generally to methods and apparatus for conducting analyzes, particularly microfluidic devices for the detection of target analytes.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: March 22, 2016
    Assignee: Illumina, Inc.
    Inventors: Mark S. Chee, Todd A. Dickinson, Kevin Gunderson, Don O'Neil
  • Patent number: 9279148
    Abstract: The present invention is directed to methods and compositions for the use of micro sphere arrays to detect and quantify a number of nucleic acid reactions. The invention finds use in genotyping, i.e. the determination of the sequence of nucleic acids, particularly alterations such as nucleotide substitutions (mismatches) and single nucleotide polymorphisms (SNPs). Similarly, the invention finds use in the detection and quantification of a nucleic acid target using a variety of amplification techniques, including both signal amplification and target amplification. The methods and compositions of the invention can be used in nucleic acid sequencing reactions as well. All applications can include the use of adapter sequences to allow for universal arrays.
    Type: Grant
    Filed: June 10, 2013
    Date of Patent: March 8, 2016
    Assignee: Illumina, Inc.
    Inventors: Kevin Gunderson, John R. Stuelpnagel, Mark S. Chee, Jian-Bing Fan
  • Publication number: 20160053310
    Abstract: A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.
    Type: Application
    Filed: October 9, 2015
    Publication date: February 25, 2016
    Applicant: ILLUMINA, INC.
    Inventors: Min-Jui Richard Shen, Jonathan Mark Boutell, Kathryn M. Stephens, Mostafa Ronaghi, Kevin Gunderson, Bala Murali Venkatesan, M. Shane Bowen, Kandaswamy Vijayan
  • Publication number: 20150353592
    Abstract: Embodiments of the present disclosure include methods and compositions for functionalizing molecules, such as oligonucleotides, with functional groups, including polyhistidine tags useful in affinity methods. Some embodiments include methods for modifying and purifying complex mixtures of molecules by exchange of functional tags.
    Type: Application
    Filed: May 20, 2015
    Publication date: December 10, 2015
    Applicant: Illumina, Inc.
    Inventors: Frank J. Steemers, Kevin Gunderson, Kerri York, Ryan Christopher Smith
  • Publication number: 20150337370
    Abstract: A technique for sequencing nucleic acids in an automated or semi-automated manner is disclosed. Sample arrays of a multitude of nucleic acid sites are processed in multiple cycles to add nucleotides to the material to be sequenced, detect the nucleotides added to sites, and to de-block the added nucleotides of blocking agents and tags used to identify the last added nucleotide. Multiple parameters of the system are monitored to enable diagnosis and correction of problems as they occur during sequencing of the samples. Quality control routines are run during sequencing to determine quality of samples, and quality of the data collected.
    Type: Application
    Filed: August 4, 2015
    Publication date: November 26, 2015
    Applicant: ILLUMINA, INC.
    Inventors: Robert C. Kain, David L. Heiner, Chanfeng Zhao, Kevin Gunderson
  • Patent number: 9169513
    Abstract: A method including (a) providing an amplification reagent including an array of sites, and a solution having different target nucleic acids; and (b) reacting the amplification reagent to produce amplification sites each having a clonal population of amplicons from a target nucleic acid from the solution. The reacting can include simultaneously transporting the nucleic acids to the sites at an average transport rate, and amplifying the nucleic acids that transport to the sites at an average amplification rate, wherein the average amplification rate exceeds the average transport rate. The reacting can include producing a first amplicon from a nucleic acid that transports to each of the sites, and producing subsequent amplicons from the nucleic acid or from the first amplicon, wherein the average rate at which the subsequent amplicons are generated exceeds the average rate at which the first amplicon is generated.
    Type: Grant
    Filed: October 13, 2014
    Date of Patent: October 27, 2015
    Assignee: ILLUMINA, INC.
    Inventors: Min-Jui Richard Shen, Jonathan Mark Boutell, Kathryn M. Stephens, Mostafa Ronaghi, Kevin Gunderson, Bala Murali Venkatesan, M. Shane Bowen, Kandaswamy Vijayan
  • Publication number: 20150284784
    Abstract: This invention provides methods of amplifying genomic DNA to obtain an amplified representative population of genome fragments. Methods are further provided for obtaining amplified genomic DNA representations of a desired complexity. The invention further provides methods for simultaneously detecting large numbers of typable loci for an amplified representative population of genome fragments. Accordingly the methods can be used to genotype individuals on a genome-wide scale.
    Type: Application
    Filed: May 18, 2015
    Publication date: October 8, 2015
    Inventors: Kevin GUNDERSON, Frank STEEMERS