Abstract: The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.

Abstract: There is disclosed a method of and a system for generating a unique identifier for a subject. Biometric data related to the subject is received. Identification markers from the biometric data are extracted. The unique identifier is generated from the extracted identification markers by identifying a given domain specific feature which has a predetermined identity compared to other domain specific features. Feature values are generated based on the biometric data and stored in a user profile of the subject.

Abstract: The present invention is directed to a topical formulation comprising 1) a dispersed phase comprising: 5 to 15% w/w (percentage weight/weight) nicotinamide; 10 to 60% w/w of a partition coefficient enhancer (Pc enhancer), having a structure of the general formula: CnH2n+2O2 where n represents an integer from 3 to 6 inclusive; and ?10% water and 2) a continuous phase, wherein the formulation has a pH above 4.0. The present invention is also directed to a pharmaceutical composition comprising the topical formulation according to the invention, a pharmaceutical composition according to the invention for use in therapy, and the use of the topical formulation as a cosmetic agent.

Abstract: A sensing system comprising a hand-held sensing device with a vibracoustic sensor module (VSM). The VSM comprises a voice coil component comprising a coil holder supporting wire windings; a magnet component comprising a magnet supported by a frame, a magnet gap configured to receive at least a portion of the voice coil component in a spaced and moveable manner; a connector connecting the voice coil component to the magnet component, the connector being compliant and permitting relative movement of the voice coil component and the magnet component; a diaphragm configured to induce a movement of the voice coil component in the magnet gap responsive to incident acoustic waves; a housing for retaining the vibroacoustic sensor module having a handle end and a sensor end, the sensor end having an opening, the VSM positioned such that at least a portion of the diaphragm extends across the opening.

Abstract: The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.

Abstract: A sensing system comprising a hand-held sensing device with a vibracoustic sensor module (VSM). The VSM comprises a voice coil component comprising a coil holder supporting wire windings; a magnet component comprising a magnet supported by a frame, a magnet gap configured to receive at least a portion of the voice coil component in a spaced and moveable manner; a connector connecting the voice coil component to the magnet component, the connector being compliant and permitting relative movement of the voice coil component and the magnet component; a diaphragm configured to induce a movement of the voice coil component in the magnet gap responsive to incident acoustic waves; a housing for retaining the vibroacoustic sensor module having a handle end and a sensor end, the sensor end having an opening, the VSM positioned such that at least a portion of the diaphragm extends across the opening.

Abstract: The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.

Abstract: A sensing system comprising a a hand-held sensing device with a vibracoustic sensor module (VSM). The VSM comprises a voice coil component comprising a coil holder supporting wire windings; a magnet component comprising a magnet supported by a frame, a magnet gap configured to receive at least a portion of the voice coil component in a spaced and moveable manner; a connector connecting the voice coil component to the magnet component, the connector being compliant and permitting relative movement of the voice coil component and the magnet component; a diaphragm configured to induce a movement of the voice coil component in the magnet gap responsive to incident acoustic waves; a housing for retaining the vibroacoustic sensor module having a handle end and a sensor end, the sensor end having an opening, the VSM positioned such that at least a portion of the diaphragm extends across the opening.

Abstract: The present invention provides a composition for topical administration of a polyhydroxy acid, such as lactobionate and especially zinc lactobionate, and low pH to an external body surface such as skin. The composition is designed to be highly effective in delivering low pH and zinc lactobionate across the layers of the skin to more effectively treat and prevent skin conditions involving a defective skin barrier such as eczema and severe dry skin.

Abstract: A porous polymeric support for biological cells is prepared having a total pore volume of at least 75% formed by a plurality of voids having an average diameter within a range of from 1 and 150 .mu.m interconnected by holes. The support is prepared by forming an emulsion containing monomers and/or prepolymers in a continuous phase and having an internal phase that forms the voids of the support, and polymerizing the monomers and/or prepolymers in the continuous phase. The emulsion may be a water-in-oil emulsion with the monomers and/or prepolymers in the oil. Biological cells are introduced into at least the voids of the support. Preferably, the voids have an average size 3 to 15 times the cell size and the holes have an average size 1 to 8 times the cell size. A compound may be produced by passing reactants into the voids via the interconnecting holes to contact the cells in the voids to cause the cells to produce the compound.

Abstract: A porous polymeric material has cell sizes within the range 100 to 0.5 .mu.m and total pore volume with respect to the overall volume of the material in the range 75 to 98% and includes cross-linked polycondensation polymeric material. The material can be made from a high internal phase emulsion in which the cross-linked polycondensation polymer is formed in the continuous phase. The materials are preferably open interconnected cellular structures. They can be made of a wide range of polycondensation materials. The materials are thus highly porous and light weight and have a range of properties depending primarily on their constituent polycondensation materials.

Abstract: The present invention relates to oral compositions such as dentifrices or mouthwashes.By inclusion therein of a shorter chain mono- and dialkylphosphate as surfactant, a mild product is obtained which also has improved anti-caries properties.Preferred are sodium mono- and di-octyl phosphates for use in these compositions.

Abstract: A porous polymeric material has cell sizes within the range 100 to 0.5 .mu.m and total pore volume with respect to the overall volume of the material in the range 75 to 98% and includes cross-linked polycondensation polymeric material. The material can be made from a high internal phase emulsion in which the cross-linked polycondensation polymer is formed in the continuous phase. The materials are preferably open interconnected cellular structures. They can be made of a wide range of polycondensation materials. The materials are thus highly porous and light weight and have a range of properties depending primarily on their constituent polycondensation materials.