Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g.

Abstract: Methods of identifying and using FAM150A agents, FAM150B agents, and FAM150 antagonists are provided. Methods of identifying and using LTK agonists (including LTK agonist antibodies, FAM150A agents, and FAM150B agents) and FAM150 antagonists are provided. Such methods include, but are not limited to, methods of treating cancer, methods of treating immune disorders such as autoimmune diseases, and methods of treating neurodegenerative diseases.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: This invention provides systems for analyzing substrates. Also provided by the invention are improved optical systems for enhanced multiplex illumination, optical systems with compact multi-wavelength illumination architectures, optical systems for enhanced detection of optical signals, and optical systems for reduced autofluorescence background noise.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: The present invention relates to a system and method for helping people abstain from addictive behaviors by utilizing an Internet-based software program to build a users' motivation to abstain, develop coping strategies for dealing with urges and cravings, learn how to analyze their behavior in terms of established goals and solve problems that impede their progress, to set goals and develop healthy, pro-social activities, and to develop a specific plan to change their behaviors. An automated but personalized email system encourages their persistence in continuing with their recovery plan, reminds them of their identified triggers, strategies they've chosen to deal with them, and reminders to engage in the pro-social activities they've chosen. A smartphone application, in addition to the features of the email method, includes a personalized text messaging feature for reaching out to others for social support.

Abstract: The present invention relates to a system and method for motivating heavy drinking college students to reduce their drinking and alcohol-related problems by utilizing a computer-based software program to screen for heavy drinking and for those who screen positive, provide a comprehensive assessment of drinking and alcohol-related problems, provide personalized feedback to the user with relevant norms, assist users in resolving their ambivalence about changing, and help them develop a plan of action to achieve the goals of drinking less and having fewer alcohol-related problems. The method includes a way for University administrators to implement the system on a campus-wide basis, customize the system to their specific campus and its needs, manage the dataset, and generate outcome reports that measure pertinent clinical outcomes of the program.

Abstract: Computer implemented methods, and systems performing such methods for processing signal data from analytical operations and systems, and particularly in processing signal data from sequence-by-incorporation processes to identify nucleotide sequences of template nucleic acids and larger nucleic acid molecules, e.g., genomes or fragments thereof.

Abstract: A clock and data recovery (CDR) system that generates one or more clock signals from a received data stream and determines an optimal clock signal to associate with the incoming data stream. The system includes a candidate clock generation circuit that operates to receive the incoming data stream and generate candidate clock signals. A transition density detector circuit determines a transition density parameter associated with each of the candidate clock signals. A controller operates to determine the optimal clock signal based on the transition density parameters.

Abstract: An apparatus and method for fault detection and isolation in an optical network is disclosed in which each node determines an appropriate response to a line fault or an equipment fault, obviating the need for a central computer to coordinate the actions of each node in response to a fault. Each network node includes a local controller and restoration elements for detecting and responding to faults. Each local controller correllates a first set of optical characteristics measured by optical detectors with the local node with a second set of optical characteristics for the channels reported to the local node from an upstream optical element, such as a neighboring upstream node, to determine if a line switch or equipment switch is required. In a preferred embodiment, each node is communicatively coupled to its neighboring node via an optical supervisory channel, with the neighboring nodes communicating status messages and data on channel characteristics via the optical supervisory channel.

Abstract: An apparatus is provided for illuminating the interior of an automotive passenger vehicle for ingress and egress. The apparatus comprises a lighting device integrated into the periphery of a sun visor or similar object. The lighting device is typically activated by a remote entry device, a door opening, or by an interior switch. The apparatus is particularly applicable where overhead interior lighting is impractical, such as in convertibles and other types of vehicles with removable tops. The lighting device may be customized for color and intensity, as well as for physical configuration. The apparatus can also be used in lieu of conventional interior roof lighting as a manufacturing cost reduction.

Abstract: A clock and data recovery (CDR) system that generates one or more clock signals from a received data stream and determines an optimal clock signal to associate with the incoming data stream. The system includes a candidate clock generation circuit that operates to receive the incoming data stream and generate candidate clock signals. A transition density detector circuit determines a transition density parameter associated with each of the candidate clock signals. A controller operates to determine the optimal clock signal based on the transition density parameters.