Patents by Inventor Kevin Hughes

Kevin Hughes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250127435
    Abstract: A blood glucose sensing system includes a plurality of physiological sensors. The system can estimate blood glucose based on discrete invasive blood glucose estimates from a blood sample, discrete noninvasive blood glucose estimates derived from optical sensors, and continuously-calculated blood glucose estimates derived from a nonlinear state-space model of glucose and insulin reactions within a human body. The state-space model has user-entered values corresponding to their insulin and meal intake. The user's blood glucose is estimated from a combination of the discrete invasive blood glucose estimates, the discrete noninvasive blood glucose estimates and the continuously-calculated blood glucose estimate.
    Type: Application
    Filed: November 20, 2024
    Publication date: April 24, 2025
    Inventors: Kevin Hughes Pauley, Hoi Wong, Jesse Chen, Mathew Paul
  • Publication number: 20250127861
    Abstract: Embodiments of the present disclosure provide insulin formulations having a near neutral pH and improved pharmacokinetic/pharmacodynamic properties, and uses in insulin infusion devices that may provide extended infusion period up to 7-14 days. Also provided are systems for administering insulin, the system may include a first reservoir, a second reservoir, an insulin pump configured to administer contents of the first reservoir or the second reservoir, and one or more hardware processors in communication with the insulin pump.
    Type: Application
    Filed: November 21, 2024
    Publication date: April 24, 2025
    Inventors: Massi Joe E. Kiani, Kevin Hughes Pauley, Venkatramanan Krishnamani
  • Patent number: 12266438
    Abstract: Systems and methods for wireless electronic communication between a medical apparatus and a remote electronic computing device comprise generating and outputting by the medical apparatus an output signal, including: encoding data in the output signal according to a predetermined characteristic of the output signal; receiving and decoding by the remote electronic computing device the encoded data in the output signal; and establishing a pairing between the medical apparatus and the remote electronic computing device.
    Type: Grant
    Filed: October 11, 2023
    Date of Patent: April 1, 2025
    Assignee: QUASURAS, INC.
    Inventors: Hugh Molesworth, Kevin Hughes, Marc Goldman, Pravin Pillai, Paul M. Diperna
  • Patent number: 12263286
    Abstract: A system for mixing a batch of medicament has a pump actuator, control valve actuators, a source of concentrate, and a purified water source, all connected by a fluid circuit. A controller controls various control valves to open fluid channels from the source of concentrate and from the purified water source to connect a junction of the fluid circuit to the concentrate container and the purified water source. The controller also controls the pump actuator and a water pump to flow water and concentrate through the junction into a mixing container, such that the mixture of the concentrate and the water requires additional dilution to form a ready-to-use medicament. The controller samples the mixture and calculate an additional quantity of water to add based on the sampling.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: April 1, 2025
    Assignee: NxStage Medical, Inc.
    Inventors: Goetz Friederichs, Kevin Hughes
  • Publication number: 20250090057
    Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.
    Type: Application
    Filed: October 16, 2024
    Publication date: March 20, 2025
    Inventors: Cristiano Dalvi, Ferdyan Lesmana, Hung The Vo, Jeroen Poeze, Jesse Chen, Kevin Hughes Pauley, Mathew Paul, Sean Merritt, Thomas B. Blank, Massi Joe E. Kiani
  • Publication number: 20250082238
    Abstract: A minimal action, invasive blood constituent device can streamline the process for the self-monitoring of blood-related tests by holding and facilitating the use of some or all of the tools for obtaining and testing a blood sample. The device can include a slider, that when pumped, causes the device to spring-load a lancet and eject a testing strip. The device can include a trigger that, when pressed, activates the lancet by unloading the spring. A strip-lancet apparatus can combine the roles of two disposable products-a testing strip and a lancing needle-into an apparatus that can be configured for piercing the testing site as well as receiving the blood sample. A testing strip apparatus can facilitate the use and/or disposal of testing strips. A lancet apparatus can facilitate the use and/or disposal of lancets.
    Type: Application
    Filed: September 23, 2024
    Publication date: March 13, 2025
    Inventors: Gregory A. Olsen, Sai Kong Frank Lee, Hung The Vo, Kevin Hughes Pauley
  • Publication number: 20250032711
    Abstract: A system which provides closed loop insulin administration is disclosed. The system includes redundant glucose sensors which may be interleaved in order to provide monitoring when one of the glucose sensors is in a settling period. The system may include a disease management unit which includes both a glucose sensor and an insulin pump. A closed loop disease management system which bases insulin administration on accurate glucose measurements may improve a patient's quality of life.
    Type: Application
    Filed: July 31, 2024
    Publication date: January 30, 2025
    Inventors: Massi Joe E. Kiani, Venkatramanan Krishnamani, Hung The Vo, Sai Kong Frank Lee, Kevin Hughes Pauley, Cristiano Dalvi, Jeroen Poeze, Jesse Chen, Gregory A. Olsen, Derek Treese
  • Patent number: 12178572
    Abstract: A blood glucose sensing system includes a plurality of physiological sensors. The system can estimate blood glucose based on discrete invasive blood glucose estimates from a blood sample, discrete noninvasive blood glucose estimates derived from optical sensors, and continuously-calculated blood glucose estimates derived from a nonlinear state-space model of glucose and insulin reactions within a human body. The state-space model has user-entered values corresponding to their insulin and meal intake. The user's blood glucose is estimated from a combination of the discrete invasive blood glucose estimates, the discrete noninvasive blood glucose estimates and the continuously-calculated blood glucose estimate.
    Type: Grant
    Filed: January 31, 2024
    Date of Patent: December 31, 2024
    Assignee: Masimo Corporation
    Inventors: Kevin Hughes Pauley, Hoi Wong, Jesse Chen, Mathew Paul
  • Patent number: 12178852
    Abstract: Embodiments of the present disclosure provide insulin formulations having a near neutral pH and improved pharmacokinetic/pharmacodynamic properties, and uses in insulin infusion devices that may provide extended infusion period up to 7-14 days. Also provided are systems for administering insulin, the system may include a first reservoir, a second reservoir, an insulin pump configured to administer contents of the first reservoir or the second reservoir, and one or more hardware processors in communication with the insulin pump.
    Type: Grant
    Filed: September 28, 2021
    Date of Patent: December 31, 2024
    Assignee: Willow Laboratories, Inc.
    Inventors: Massi Joe E. Kiani, Kevin Hughes Pauley, Venkatramanan Krishnamani
  • Publication number: 20240415426
    Abstract: Systems, methods, and apparatuses for enabling non-invasive, physiological sensors to obtain physiological measurements from a region of tissue of a patient are disclosed. Anchoring components can attach to patient tissue sites and sensor heads such that the tissue sites do not move during sensing. Interlocking mechanisms maintain tissue sites within a limited range of horizontal movement and vertical distance from the sensor head.
    Type: Application
    Filed: June 27, 2024
    Publication date: December 19, 2024
    Inventors: Hung The Vo, Cristiano Dalvi, Kevin Hughes Pauley
  • Publication number: 20240420590
    Abstract: Systems and methods for a comprehensive and personalized approach to health and lifestyle coaching are described. The system may determine health metrics of a user based on detected physiological parameters. The health metrics may be used to determine health recommendations and transmit feedback to the user based on user compliance with the recommendations.
    Type: Application
    Filed: June 26, 2024
    Publication date: December 19, 2024
    Inventors: Kevin Hughes Pauley, Merlin Stonecypher, Anderson Briglia, Gerry Hammarth, Gregory A. Olsen, Jesse Chen
  • Publication number: 20240407677
    Abstract: A noninvasive physiological sensor can include a first body portion and a second body portion coupled to each other and configured to at least partially enclose a user's finger. The sensor can further include a first probe coupled to one or more emitters and a second probe coupled to a detector. The first probe can direct light emitted from the one or more emitters toward tissue of the user's finger and the second probe can direct light attenuated through the tissue to the detector. The first and second probes can be coupled to the first and second body portions such that when the first and second body portions are rotated with respect to one another, ends of the first and second probes can be moved in a direction towards one another to compress the tissue of the user's finger.
    Type: Application
    Filed: June 18, 2024
    Publication date: December 12, 2024
    Inventors: Hung The Vo, Kevin Hughes Pauley, Cristiano Dalvi, Sean Merritt, Jesse Chen, Jeroen Poeze, Ferdyan Lesmana, Ruiqi Long
  • Publication number: 20240406125
    Abstract: Described herein are systems and methods for monitoring plant health by communicating with plant-associated persona(s) via artificial intelligence. These systems and methods can communicate information about the health of plants in a natural-language format through the use of plant-based sensors for collecting data on plant health, analytical models and processors for processing the data on plant health, large language models for converting the data on plant health into a persona-guided, natural-language format, and user devices for receiving the data on plant health in the natural-language format.
    Type: Application
    Filed: May 31, 2024
    Publication date: December 5, 2024
    Applicant: ePlant, Inc.
    Inventors: Roger George HINE, Jesse Thomas, Graham Lancaster HINE, Evan T. DELLOR, Kevin Hugh REA
  • Publication number: 20240390608
    Abstract: Various spirometer-inhaler systems and devices are disclosed. The spirometer-inhaler system may estimate physiological parameters of a user based on the user's inhaled and/or exhaled breaths received by the spirometer-inhaler device. The spirometer-inhaler device may comprise one or more flow paths. A first flow path may direct medication from a medicine canister to an opening of the device. A second flow path may direct a user's exhaled breath from the opening of the device to one or more flow measurement devices.
    Type: Application
    Filed: June 3, 2024
    Publication date: November 28, 2024
    Inventors: Kevin Hughes Pauley, Sai Kong Frank Lee
  • Patent number: 12150760
    Abstract: An optical physiological sensor configured to perform high speed spectral sweep analysis of sample tissue being measured to non-invasively predict an analyte level of a patient. An emitter of the optical physiological sensor can be regulated to operate at different temperatures to emit radiation at different wavelengths. Variation in emitter drive current, duty cycle, and forward voltage can also be used to cause the emitter to emit a range of wavelengths. Informative spectral data can be obtained during the sweeping of specific wavelength regions of sample tissue.
    Type: Grant
    Filed: December 14, 2022
    Date of Patent: November 26, 2024
    Assignee: Willow Laboratories, Inc.
    Inventors: Cristiano Dalvi, Ferdyan Lesmana, Hung The Vo, Jeroen Poeze, Jesse Chen, Kevin Hughes Pauley, Mathew Paul, Sean Merritt, Thomas B. Blank, Massi Joe E. Kiani
  • Publication number: 20240382625
    Abstract: Some embodiments disclosed herein pertain to indicator compounds used to detect the presence of and/or an amount of an analyte. In some embodiments, the indicator compounds are fusion proteins. In some embodiments, when the analyte binds to the indicator compound, the indicator compound undergoes a conformational change. In some embodiments, the conformational change results in a luminescent signal that allows quantification of the amount of analyte present.
    Type: Application
    Filed: March 7, 2024
    Publication date: November 21, 2024
    Inventors: Venkatramanan Krishnamani, Sergei Balashov, Kevin Hughes Pauley, Ruiqi Long, Hung The Vo
  • Patent number: 12128213
    Abstract: A system which provides closed loop insulin administration is disclosed. The system includes redundant glucose sensors which may be interleaved in order to provide monitoring when one of the glucose sensors is in a settling period. The system may include a disease management unit which includes both a glucose sensor and an insulin pump. A closed loop disease management system which bases insulin administration on accurate glucose measurements may improve a patient's quality of life.
    Type: Grant
    Filed: January 28, 2021
    Date of Patent: October 29, 2024
    Assignee: Willow Laboratories, Inc.
    Inventors: Massi Joe E. Kiani, Venkatramanan Krishnamani, Hung The Vo, Sai Kong Frank Lee, Kevin Hughes Pauley, Cristiano Dalvi, Jeroen Poeze, Jesse Chen, Gregory A. Olsen, Derek Treese
  • Patent number: 12131661
    Abstract: Systems and methods for a comprehensive and personalized approach to health and lifestyle coaching are described. The system may determine health metrics of a user based on detected physiological parameters. The health metrics may be used to determine health recommendations and transmit feedback to the user based on user compliance with the recommendations.
    Type: Grant
    Filed: October 2, 2020
    Date of Patent: October 29, 2024
    Assignee: Willow Laboratories, Inc.
    Inventors: Kevin Hughes Pauley, Merlin Stonecypher, Anderson Briglia, Gerry Hammarth, Gregory A. Olsen, Jesse Chen
  • Patent number: 12127838
    Abstract: A minimal action, invasive blood constituent device can streamline the process for the self-monitoring of blood-related tests by holding and facilitating the use of some or all of the tools for obtaining and testing a blood sample. The device can include a slider, that when pumped, causes the device to spring-load a lancet and eject a testing strip. The device can include a trigger that, when pressed, activates the lancet by unloading the spring. A strip-lancet apparatus can combine the roles of two disposable products—a testing strip and a lancing needle—into an apparatus that can be configured for piercing the testing site as well as receiving the blood sample. A testing strip apparatus can facilitate the use and/or disposal of testing strips. A lancet apparatus can facilitate the use and/or disposal of lancets.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: October 29, 2024
    Assignee: WILLOW LABORATORIES, INC.
    Inventors: Gregory A. Olsen, Sai Kong Frank Lee, Hung The Vo, Kevin Hughes Pauley
  • Publication number: 20240324910
    Abstract: Systems, methods, apparatuses, and medical devices for harmonizing data from a plurality of non-invasive sensors are described. A physiological parameter can be determined by harmonizing data between two or more different types of non-invasive physiological sensors interrogating the same or proximate measurement sites. Data from one or more first non-invasive sensors can be utilized to identify one or more variables that are useful in one or more calculations associated with data from one or more second non-invasive sensors. Data from one or more first non-invasive sensors can be utilized to calibrate one or more second non-invasive sensors. Non-invasive sensors can include, but are not limited to, an optical coherence tomography (OCT) sensor, a bio-impedance sensor, a tissue dielectric constant sensor, a plethysmograph sensor, or a Raman spectrometer.
    Type: Application
    Filed: April 23, 2024
    Publication date: October 3, 2024
    Inventors: Jesse Chen, Sean Merritt, Cristiano Dalvi, Ferdyan Lesmana, Hung The Vo, Kevin Hughes Pauley, Jeroen Poeze, Ruiqi Long, Stephen L. Monfre