Patents by Inventor Kevin J. Koeller

Kevin J. Koeller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antiviral compounds and methods for treating infections caused by double-stranded DNA viruses
    Patent number: 9982020
    Abstract: The present invention relates to polyamide compounds and their use in pharmaceutical compositions and in medical applications for the treatment of human papillomavirus infections and/or polyomavirus infections.
    Type: Grant
    Filed: August 5, 2015
    Date of Patent: May 29, 2018
    Inventors: James K. Bashkin, Terri Grace Edwards, Christopher Fisher, George D. Harris, Jr., Kevin J. Koeller
  • Methods for treating papilloma virus infection
    Patent number: 9333232
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells infected with papilloma virus (PV).
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: May 10, 2016
    Assignees: NanoVir LLC, THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: James K. Bashkin, Terri Grace Edwards, Christopher Fisher, Kevin J. Koeller
  • Compounds for treating papilloma virus infection
    Patent number: 9290551
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
    Type: Grant
    Filed: February 25, 2015
    Date of Patent: March 22, 2016
    Assignees: NanoVir LLC, THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING INFECTIONS CAUSED BY DOUBLE-STRANDED DNA VIRUSES
    Publication number: 20150329596
    Abstract: The present invention relates to polyamide compounds and their use in pharmaceutical compositions and in medical applications for the treatment of human papillomavirus infections and/or polyomavirus infections.
    Type: Application
    Filed: August 5, 2015
    Publication date: November 19, 2015
    Inventors: James K. BASHKIN, Terri Grace Edwards, Christopher Fisher, George D. Harris, JR., Kevin J. Koeller
  • Guanidinyl-substituted polyamides useful for treating human papilloma virus
    Patent number: 9133228
    Abstract: Polyamide compositions containing guanidinyl radicals, including tetramethylguanidinyl radicals, are described. These polyamides are useful for medical applications, for example, for treating human papilloma virus infections.
    Type: Grant
    Filed: October 10, 2012
    Date of Patent: September 15, 2015
    Assignees: NanoVir LLC, THE CURATORS OF THE UNIVERSITY OF MISSOURI
    Inventors: James Bashkin, Terri G. Edwards, Christopher Fisher, George D. Harris, Jr., Kevin J. Koeller
  • COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION
    Publication number: 20150239943
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
    Type: Application
    Filed: February 25, 2015
    Publication date: August 27, 2015
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • Compounds for treating papilloma virus infection
    Patent number: 8993609
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
    Type: Grant
    Filed: January 25, 2012
    Date of Patent: March 31, 2015
    Assignees: Nanovir, LLC, The Curators of the University of Missouri
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • COMPOUNDS FOR TREATING PAPILLOMA VIRUS INFECTION
    Publication number: 20120225809
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells and subjects infected with papilloma virus.
    Type: Application
    Filed: January 25, 2012
    Publication date: September 6, 2012
    Applicant: Nanovir, LLC
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • Polyamides containing amino butyric acid-based building blocks
    Patent number: 8119677
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells infected with papilloma virus.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: February 21, 2012
    Assignee: NanoVir, LLC
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • Compounds for Treating Papilloma Virus Infection
    Publication number: 20100015084
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells infected with papilloma virus.
    Type: Application
    Filed: August 3, 2009
    Publication date: January 21, 2010
    Applicant: NANOVIR, LLC
    Inventors: James K. BASHKIN, Terri Grace EDWARDS, Christopher FISHER, Kevin J. KOELLER
  • Methods for Treating Papilloma Virus Infection
    Publication number: 20090306164
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells infected with papilloma virus (PV).
    Type: Application
    Filed: August 3, 2009
    Publication date: December 10, 2009
    Applicant: NANOVIR, LLC
    Inventors: James K. BASHKIN, Terri Grace EDWARDS, Christopher FISHER, Kevin J. KOELLER
  • Polyamides for treating human papilloma virus
    Patent number: 7589171
    Abstract: The present invention relates to polyamide compositions and therapies for treating cells infected with human papilloma virus (HPV).
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: September 15, 2009
    Assignee: Nanovir, LLC
    Inventors: James K. Bashkin, Kevin J. Koeller, Terri Grace Edwards, Christopher Fisher
  • Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
    Patent number: 6916847
    Abstract: The invention relates to polycyclic aryl and heteroaryl substituted 4-pyrone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: July 12, 2005
    Assignee: Pharmacia Corporation
    Inventors: Michael S. South, Chun C. Ma, Kevin J. Koeller, Hayat K. Rahman, William L. Neumann
  • Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade
    Patent number: 6875791
    Abstract: The invention relates to polycyclic aryl and heteroaryl substituted 4-pyrone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Grant
    Filed: April 4, 2001
    Date of Patent: April 5, 2005
    Assignee: Pharmacia Corporation
    Inventors: Michael S. South, Chun C. Ma, Kevin J. Koeller, Hayat K. Rahman, William L. Neumann
  • Alkyl/aryl hydroxy or keto thiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
    Patent number: 6852753
    Abstract: Thiepine apical sodium co-dependent bile acid transport (ASBT) inhibitors are disclosed together with methods of making the same, methods of using the same to treat hyperlipidemic conditions as well as pharmaceutical compositions containing the same compounds.
    Type: Grant
    Filed: January 15, 2003
    Date of Patent: February 8, 2005
    Assignee: Pharmacia Corporation
    Inventors: Kevin J. Koeller, Samuel J. Tremont
  • Method for the preparation of tetrahydrobenzothiepines
    Patent number: 6794544
    Abstract: Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: September 21, 2004
    Assignee: Pharmacia Corporation
    Inventors: Kevin A. Babiak, Andrew Carpenter, Shine Chou, Pierre-Jean Colson, Payman Farid, Robert Hett, Christian H. Huber, Kevin J. Koeller, Jon P. Lawson, James Li, Eduardo K. Mar, Lawrence M. Miller, Vladislav Orlovski, James C. Peterson, Mark J. Pozzo, Claire A. Przybyla, Samuel J. Tremont, Jay S. Trivedi, Grace M. Wagner, Gerald A. Weisenburger, Benxin Zhi
  • Novel mono- and di-fluorinated beozothiepine copmunds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
    Publication number: 20040176438
    Abstract: Mono-fluorinated and di-fluorinated benzothiepine apical sodium co-dependent bile acid transport (ASBT) inhibitors are disclosed together with methods of making the same, methods of using the same to treat hyperlipidemic conditions as well as pharmaceutical compositions containing the same compounds.
    Type: Application
    Filed: December 23, 2003
    Publication date: September 9, 2004
    Applicant: G.D. SEARLE, LLC
    Inventors: Samuel J. Tremont, Kevin J. Koeller
  • Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade
    Publication number: 20040162319
    Abstract: The invention relates to polycyclic aryl and heteroaryl substituted 4-pyridone compounds useful as inhibitors of serine proteases of the coagulation cascade and compounds, compositions and methods for anticoagulant therapy for the treatment and prevention of a variety of thrombotic conditions including coronary artery and cerebrovascular diseases.
    Type: Application
    Filed: February 2, 2004
    Publication date: August 19, 2004
    Applicant: Pharmacia Corporation
    Inventors: Michael S. South, Chun C. Ma, Kevin J. Koeller, Hayat K. Rahman, William L. Neumann
  • Mono- and di-fluorinated benzothiepine compounds as inhibitors of apical sodium co-dependent bile acid transport (ASBT) and taurocholate uptake
    Patent number: 6740663
    Abstract: Mono-flourinated and di-fluorinated benzothiepine apical sodium co-dependent bile acid transport (ASBT) inhibitors are disclosed together with methods of making the same, methods of using the same to treat hyperlipidemic conditions as well as pharmaceutical compositions containing the same compounds.
    Type: Grant
    Filed: November 4, 2002
    Date of Patent: May 25, 2004
    Assignee: G.D. Searle, LLC
    Inventors: Samuel Tremont, Kevin J. Koeller
  • Method for the preparation of tetrahydrobenzothiepines
    Publication number: 20040082647
    Abstract: Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds.
    Type: Application
    Filed: April 21, 2003
    Publication date: April 29, 2004
    Applicant: G.D. SEARLE, LLC
    Inventors: Kevin A. Babiak, Andrew Carpenter, Shine Chou, Pierre-Jean Colson, Payman Farid, Robert Hett, Christian H. Huber, Kevin J. Koeller, Jon P. Lawson, James Li, Eduardo K. Mar, Lawrence M. Miller, Vladislav Orlovski, James C. Peterson, Mark J. Pozzo, Claire A. Przybyla, Samuel J. Tremont, Jay S. Trivedi, Grace M. Wagner, Gerald A. Weisenburger, Benxin Zhi