Abstract: The present disclosure relates to certain (2S)—N-[(1S)-1-cyano-2-phenylethyl]-1,4-oxazepane-2-carboxamide compounds (including pharmaceutically acceptable salts thereof), that inhibit dipeptidyl peptidase 1 (DPP1) activity, to their utility in treating and/or preventing clinical conditions including respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD), to their use in therapy, to pharmaceutical compositions containing them and to processes for preparing such compounds.

Abstract: A line marking apparatus, for use in a system that includes a source of a narrow beam of radiation which extends substantially horizontally along or parallel to a line to be marked, includes a wheeled chassis and a line marking head for dispensing line marking material. The marking head is supported on the chassis for lateral movement relative thereto, which movement is controlled by a controller that includes a detector which is movable with the marking head and is positioned and directed to detect such a beam of radiation, the marking head being movable together with the detector in response to a detected beam. Lateral movement of the marking head is thereby controlled such that the head and the detector substantially follow the line to be marked irrespective of whether the chassis deviates from the line direction.

Abstract: A line marking apparatus, for use in a system that includes a source of a narrow beam of radiation which extends substantially horizontally along or parallel to a line to be marked, includes a wheeled chassis and a line marking head for dispensing line marking material. The marking head is supported on the chassis for lateral movement relative thereto, which movement is controlled by a controller that includes a detector which is movable with the marking head and is positioned and directed to detect such a beam of radiation, the marking head being movable together with the detector in response to a detected beam. Lateral movement of the marking head is thereby controlled such that the head and the detector substantially follow the line to be marked irrespective of whether the chassis deviates from the line direction.

Abstract: A line marking apparatus, for use in a system that includes a source of a narrow beam of radiation which extends substantially horizontally along or parallel to a line to be marked, includes a wheeled chassis and a line marking head for dispensing line marking material. The marking head is supported on the chassis for lateral movement relative thereto, which movement is controlled by a controller that includes a detector which is movable with the marking head and is positioned and directed to detect such a beam of radiation, the marking head being movable together with the detector in response to a detected beam. Lateral movement of the marking head is thereby controlled such that the head and the detector substantially follow the line to be marked irrespective of whether the chassis deviates from the line direction.

Abstract: A line marking apparatus includes a chassis (2) provided with wheels (4) and with means (6) for propelling the apparatus. A line marking head (12) is adapted to dispense line marking material so as to mark a line upon a surface over which the apparatus is moved. A support (14) is provided for the line marking head such that the line marking head is movable laterally relative to the chassis. Lateral movement of the line marking head is controlled by a controller which includes a detector (32) for detecting a beam of electromagnetic radiation indicative of the line to be marked and which also includes control means for moving the line marking head in response to detection of the beam by the detector, whereby lateral movement of the line marking head relative to the chassis is controlled such that the line marking head substantially follows the line to be marked irrespective of whether the chassis deviates from the direction of such line.

Abstract: The detection device that can be used for detecting objects behind clothing etc including a dielectric lens and a receive element sensitive to millimetre wave radiation. Prior art systems produce an image of a scene usually using scanning optics. This can be large and expensive. The present invention instead takes spot readings from different parts of a scene without building up an image. The spot readings are processed, and an indication given to a user if certain characteristics of the readings are observed. Typical characteristics used are the differences in absolute received power level, and the power level at different polarisations. Such characteristics are typically present is an object of interest is in the scene. Also disclosed are various methods of altering the received beam to get readings from different areas from the scene, such as changing the beam width, or beam angle.

Abstract: A detection device that can be used for detecting objects behind clothing etc including a dielectric lens and a receive element sensitive to millimetre wave radiation. Prior art systems produce an image of a scene usually using scanning optics. This can be large and expensive. The present invention instead take spot readings from different parts of a scene without building up an image. The spot readings are processed, and an indication given to a user if certain characteristics of the readings are observed. Typical characteristics used are the differences in absolute received power level, and the power level at different polarisations. Such characteristics are typically present is an object of interest is in the scene. Also disclosed are various methods of altering the received beam to get readings from different areas from the scene, such as changing the beam width, or beam angle.