Patents by Inventor Kevin John

Kevin John has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitrogen-rich macrocyclic ligands, chelation complexes thereof, and process for selective chelation of radioactive bismuth ions with the ligands
    Patent number: 10450336
    Abstract: Selective chelation of bismuth radionuclide ions from a mixture including actinium radionuclide ions involves exposing a ligand to an aqueous solution that includes bismuth radionuclide ions and actinium radionuclide ions under conditions whereby the bismuth radionuclide ions selectively chelate to the ligand for form cationic complexes of the bismuth radionuclide ions. and separating the cationic complexes of the bismuth radionuclide ions from the actinium radionuclide ions. The ligands have a structure based on a 12-membered cyclen ring and may include pendant functional groups that can be derivatized with biological targeting vectors for targeted alpha therapy.
    Type: Grant
    Filed: May 4, 2015
    Date of Patent: October 22, 2019
    Assignee: Triad National Security, LLC
    Inventors: Justin Wilson, Eva Birnbaum, Kevin John, Francois Nortier, Michael Fassbender, Valery Radchenko, Jonathan Ward Engle
  • NITROGEN-RICH MACROCYCLIC LIGANDS, CHELATION COMPLEXES THEREOF, AND PROCESS FOR SELECTIVE CHELATION OF RADIOACTIVE BISMUTH IONS WITH THE LIGANDS
    Publication number: 20150344508
    Abstract: Selective chelation of bismuth radionuclide ions from a mixture including actinium radionuclide ions involves exposing a ligand to an aqueous solution that includes bismuth radionuclide ions and actinium radionuclide ions under conditions whereby the bismuth radionuclide ions selectively chelate to the ligand for form cationic complexes of the bismuth radionuclide ions. and separating the cationic complexes of the bismuth radionuclide ions from the actinium radionuclide ions. The ligands have a structure based on a 12-membered cyclen ring and may include pendant functional groups that can be derivatized with biological targeting vectors for targeted alpha therapy.
    Type: Application
    Filed: May 4, 2015
    Publication date: December 3, 2015
    Applicant: Los Alamos National Security, LLC
    Inventors: Justin Wilson, Eva Birnbaum, Kevin John, Francois Nortier, Michael Fassbender, Valery Radchenko, Jonathan Ward Engle
  • Quantitative method of determining beryllium or a compound thereof in a sample
    Publication number: 20070141715
    Abstract: A method of determining beryllium or a beryllium compound thereof in a sample, includes providing a sample suspected of comprising beryllium or a compound thereof, extracting beryllium or a compound thereof from the sample by dissolving in a solution, adding a fluorescent indicator to the solution to thereby bind any beryllium or a compound thereof to the fluorescent indicator, and determining the presence or amount of any beryllium or a compound thereof in the sample by measuring fluorescence.
    Type: Application
    Filed: October 31, 2006
    Publication date: June 21, 2007
    Inventors: T. McCleskey, Deborah Ehler, Kevin John, Anthony Burrell, Gavin Collis, Edel Minogue, Benjamin Warner
  • Quantitative method of determining beryllium or a compound thereof in a sample
    Publication number: 20050221498
    Abstract: A method of determining beryllium or a beryllium compound thereof in a sample, includes providing a sample suspected of comprising beryllium or a compound thereof, extracting beryllium or a compound thereof from the sample by dissolving in a solution, adding a fluorescent indicator to the solution to thereby bind any beryllium or a compound thereof to the fluorescent indicator, and determining the presence or amount of any beryllium or a compound thereof in the sample by measuring fluorescence.
    Type: Application
    Filed: March 30, 2004
    Publication date: October 6, 2005
    Inventors: T. McCleskey, Deborah Ehler, Kevin John, Anthony Burrell, Gavin Collis, Edel Minogue, Benjamin Warner