Abstract: Provided is a centrifuge cassette assembly (800) for separating a fluid and related method of manufacture. The cassette assembly includes a first chamber, a second chamber (308), a fluidic channel (808) creating a fluid connection between the first chamber and the second chamber, at least one molded insertion valve (600, 700) configured to control the flow of fluid in the fluidic channel and a heating element (802) for actuating the at least one molded valve. Further provided are Normally Open Valves (NOVs) (700) and Normally Closed Valves (NCVs) (600) which are capable of insertion into, and which control the fluid flow of, the centrifuge cassette assembly.

Abstract: Methods, devices and device components are presented for reducing pathogenic biological contaminants in biological samples, in particular, methods, devices and device components for treating biological samples with electromagnetic radiation. In one aspect, the invention provides illuminators having differentially cooled light sources which exhibit improved light source longevity over conventional high intensity illuminators. In another aspect, the invention provides illuminators having closed loop feedback temperature control which produce radiant intensities and powers that are substantially constant as a function of time.