Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: A rotor of an electric motor, in particular for a power steering system, including a rotor shaft, which is directed in an axial direction, and a number of rotor cores, which are arranged coaxial to each other along the rotor shaft, and an intermediate ring arranged between two rotor cores arranged adjacent to each other in the axial direction, which intermediate ring holds the adjacent rotor cores interlockingly in a crossed orientation relative to each other.

Abstract: Provided are quinazolinone dione compounds for treating cardiac indications such as hypertrophic cardiomyopathy and diastolic dysfunction.

Abstract: The present disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (II-A), (IV), or (III) and pharmaceutical compositions thereof. The substituted quinolinone amide compounds or salts of Formula (I), (II-A), (IV), or (III) disclosed herein may be used to treat or prevent cardiac disease in an individual in need thereof.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: A stator for an electric motor has a stator base body, which has stator teeth arranged in a star shape and a stator yoke, and on whose outer circumference a number of axial slots are provided, into which joining elements projecting radially from the circumference of the stator base body are radially inserted in a form-fitting manner.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: A housing assembly for electrical storage comprises a base tray with a base and a circumferentially closed tray frame, that is formed in one piece from a metallic material; a structural frame with a plurality of frame elements and reinforcing elements that are each produced from steel material and are connected to one another to form the structural frame, the structural frame being inserted into the base tray and connected thereto; wherein the yield strength of the steel material of the structural frame is at least 10% greater than the yield strength of the metallic material of the tray frame; and a cover which is releasably connectable to the tray frame, wherein the tray frame and the cover enclose a receiving space for electrical storage.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: A rotor of an electric motor, in particular for a power steering system, including a rotor shaft, which is directed in an axial direction, and a number of rotor cores, which are arranged coaxial to each other along the rotor shaft, and an intermediate ring arranged between two rotor cores arranged adjacent to each other in the axial direction, which intermediate ring holds the adjacent rotor cores interlockingly in a crossed orientation relative to each other.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: An electric motor of a motor vehicle, in particular a steering motor, includes a housing having a motor compartment and an electronics compartment. The motor compartment and the electronics compartment are separated by a housing wall that has a plurality of openings. A stator is situated in the motor compartment and an electronics system is situated in the electronics compartment. The stator and the electronics system electrically contact one another through phase connections which project through the openings. A separating element is situated between the stator and the electronics system. The separating element at least partially covers the openings and the housing wall.

Abstract: Systems and methods for production and presentation of video content are provided. The system can include a transparent panel and a camera positioned adjacent to the transparent panel. The camera can generate a camera signal indicative of image data of a user positioned on a side of the transparent panel opposing the camera. The system can further include a memory storing instructions and a processor configured to or programmed to read the instructions stored in the memory. The processor can be configured to or programmed to: receive the camera signal; receive an overlay signal having at least one visual element; overlay the at least one visual element of the overlay signal on the transparent panel; and control a display of the at least one visual element on the transparent panel such that the at least one visual element is visible to the user and not visible to the camera.

Abstract: An electric motor has a stator and a rotor which is arranged on a motor shaft in a rotationally fixed manner. The motor shaft is rotatably mounted about a rotational axis in at least one rolling bearing within a motor housing. The rolling bearing is arranged in a bearing shield in a bearing receiving area, the outer ring of the rolling bearing is pretensioned by a spring disc which sits in the bearing receiving area in a fixed manner to the housing, and the spring disc has an opening and a number of spring elements raised axially towards the outer ring in a disc body surrounding the opening.

Abstract: An electric motor contains a motor shaft which is arranged in a motor housing. The motor shaft is rotatably mounted about a rotational axis in at least one rolling or ball bearing, which sits in a bearing receiving area and contains an outer ring and an inner ring fixed to the motor shaft. The outer ring of the rolling bearing is pretensioned by a spring disc which sits in the bearing receiving area and has a number of wave trains with alternatingly axially projecting half wave trains, and the spring disc has a number of centering elements on the inner circumference. The centering elements rest against the motor shaft when the spring disc is untensioned and is arranged at a distance to the motor shaft when the spring disc is tensioned.

Abstract: Compounds for the treatment of brain cancer are provided herein. Pharmaceutical compositions comprised of those compounds for the treatment of brain cancer are also provided herein.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.

Abstract: Substituted pyridazinone compounds, conjugates, and pharmaceutical compositions for use in the treatment of neuromuscular diseases, such as Duchenne Muscular Dystrophy (DMD), are disclosed herein. The disclosed compounds are useful, among other things, in the treating of DMD and modulating inflammatory inhibitors IL-1, IL-6 or TNF-?.