Abstract: A computing system includes a first computing platform and a virtual exchange computing platform, where the first computing platform provides an application and a first electronic value token and the virtual exchange computing platform is communicatively coupled to the first computing platform. The virtual exchange computing platform receives the information corresponding to the first electronic value token and calculates, via API functions linking to banking as a service (BaaS) functionality processed by a valuation computing platform, a valuation of the first electronic value token. The virtual exchange computing platform causes presentation, via a network and on a first user device, a user interface screen presenting a visualization of a value of the electronic value token and comprising an input and triggers, based on a received trade input from the user interface, a virtual exchange of value involving the first electronic value token.

Abstract: Inspection systems and methods of inspection are provided that include an image sensor to acquire inspection data characterizing a video of at least a portion of an asset being inspected, wherein the asset includes one or more components, and a computing system communicatively coupled to the image sensor. The computing system includes a user interface display, a processor and a memory storing instructions which, when executed by the processor causes the processor to perform operations including: receiving, from the image sensor, the inspection data, identifying, automatically, at least a first component of the one or more components, generating a graphical user interface (GUI) including the inspection data, generating a first dynamic identifier within the GUI, wherein the first dynamic identifier corresponds to the first component and is arranged to follow the first component as it moves within the GUI, and providing the GUI to the user interface display.

Abstract: This disclosure relates to planning systems and methods. The planning systems and methods disclosed herein may be utilized for planning orthopaedic procedures to restore functionality to a joint, may include determining a contact area between an implant and a cortical area of an associated bone.

Abstract: A laparoscopic medical device includes an oximeter sensor at its tip, which allows making oxygen saturation measurements laparoscopically. The laparoscopic medical device includes a probe unit and a laparoscopic tube that detachably connects with the probe unit so that the laparoscopic tube can be replaced for different patient surgeries and the probe unit can be reused for the different surgeries. The probe unit includes a number of transmitting optical fibers and the detachable laparoscopic tube includes a number of receiving optical fibers where tips of the transmitting and receiving optical fibers connect end to end. Cores of the transmitting optical fibers have smaller numerical apertures than cores of the receiving optical fibers to facilitate a high percentage of light transmission from the transmitting optical fibers to the receiving optical fibers even when the cores of the transmitting and receiving optical fibers are misaligned at their connecting ends.

Abstract: The invention relates to parathyroid hormone (PTH) variants and pharmaceutical compositions comprising same. The invention further relates to PTH compositions with improved serum half-life and peak-trough ratios, and methods of controlling serum calcium levels with the PTH variants and compositions of the invention. The invention further relates to methods of treating hypoparathyroidism and/or hypocalcemia due to hypoparathyroidism with the PTH variants and compositions of the invention.

Abstract: Example embodiments of the present disclosure provide for an example method including obtaining component data associated with a plurality of components. The example method includes generating an index of the component data and obtaining user input data indicative of a request. The example method includes processing the user input data to determine an intent associated with the request and obtaining, based on the intent, data indicative of one or more components from the index. The example method includes determining a rank for at least one respective component of the one or more components. The example method includes updating a user interface to display the one or more components, wherein the components are displayed based at least in part on the rank of the respective component. The example method can include generating modular spaces composed of a plurality of components to generate composite application interfaces which can include cross-application functionalities.

Abstract: A gaming system includes a processor and a memory storing instructions thereon. The instructions cause the processor to initiate gameplay of a bingo game having a progressive jackpot and cause a first outcome of the bingo game to be evaluated according to a first progressive jackpot trigger condition for a first stage of the progressive jackpot. The instructions further cause the processor to increment the value of the progressive jackpot value, update, based on the value of the progressive jackpot after being incremented, the progressive jackpot to a second stage, and cause a second outcome of the bingo game to be evaluated according to a second progressive jackpot trigger condition for the second stage of the progressive jackpot.

Abstract: An apparatus for use in the oil and gas industry for installation of drilling and production liners and sub-sea casing strings into a borehole through a drilling fluid on a workstring using a running tool with the benefits of surge pressure reduction is disclosed. In an embodiment, a convertible diverter device has a housing with diverting flow path which diverts fluid from its axial passageway to the annular space outside the convertible diverter device, and a closing sleeve, residing within the housing, the closing sleeve having a diverting position and a closed position. In the diverting position, the diverting flow path is not blocked by the closing sleeve, and in the closed position the closing sleeve sealingly blocks the diverting flow path, so only the axial passageway through the housing is accessible for passage of fluid and tools.

Abstract: Embodiments described herein relate to systems and methods for authenticating a candidate product in a rendering of a first user and a candidate product to determine whether the candidate product is an authentic branded product and generating a branded product interaction which is provided to a second user. The system generates digital instructions and outputs for an online web application, device hosted application, smart device, or similar system. In one embodiment, the system provides the branded product interaction that matches device capacity, user context, and product availability.

Abstract: A network device may originate a route, and may designate the route as a first colored route having a first color. The network device may advertise the first colored route to a first intermediate network device to cause the first intermediate network device to propagate the first colored route to an ingress network device over a first colored border gateway protocol session. The network device may designate the route as a second colored route having a second color, and may advertise the second colored route to a second intermediate network device to cause the second intermediate network device to propagate the second colored route to the ingress network device over a second colored border gateway protocol session.

Abstract: In one embodiment, a method for authenticating a computer system is provided. The method includes: receiving, by a processor, device identifier information associated with the computer system; generating, by the processor, a device identifier and an enrollment token based on the device identifier information; communicating, by the processor, the device identifier and the enrollment token to the computer system; receiving, by the processor, key data in response to the communicating; and performing, by the processor, authentication of the computer system based on the key data.

Abstract: Compounds, compositions, and methods for making and using the compounds for treatment of cancer are provided herein. Mechanistically, these compounds were found to bind to RPS23 and were effective in activating the inducible stress response.

Abstract: Proteins, nucleic acids encoding the proteins, compositions comprising the proteins, and methods are provided. The proteins have the ability to be self-targeted to ICAM-1 and, if desired, enzymatically-released at acidic pH. The ICAM-1-targeting peptides are provided as single copies or multiples repeats, and can be separated by linkers from the enzyme segment, from which the ICAM-1 targeting peptides can be released, if desired, at acidic pH. These fusion proteins enhance the activity of the enzyme segment within or liberated from the fusion protein, and provide increased recognition and targeting of diseased organs, transport from the bloodstream across the endothelium into said diseased organ, and intracellular uptake and lysosomal trafficking by cells in them, both in peripheral tissues and the central nervous system. Representative nucleotide and amino acid sequences of these fusion proteins, as well as in vitro, cellular, and in vivo animal data are provided.

Abstract: A surface cleaner (10) includes a main body (12), a base (14), and a column (18) extending from the base. A supply tank (42) extends around a first portion of the column. A first end of the supply tank is on a first side of the column. A second end of the supply tank is on a second side of the column. A recovery tank (46) extends around a second portion of the column. A first end of the recovery tank is on the first side of the column. A second end of the recovery tank is on the second side of the column. The first end of the supply tank is adjacent the first end of the recovery tank. The second end of the supply tank is spaced from the second end of the recovery tank. A battery (98) is coupled to the main body between the second ends of the supply and recovery tanks.

Abstract: A deep learning-based digital/virtual staining method and system enables the creation of digitally/virtually-stained microscopic images from label or stain-free samples. In one embodiment, the method of generates digitally/virtually-stained microscope images of label-free or unstained samples using fluorescence lifetime (FLIM) image(s) of the sample(s) using a fluorescence microscope. In another embodiment, a digital/virtual autofocusing method is provided that uses machine learning to generate a microscope image with improved focus using a trained, deep neural network. In another embodiment, a trained deep neural network generates digitally/virtually stained microscopic images of a label-free or unstained sample obtained with a microscope having multiple different stains. The multiple stains in the output image or sub-regions thereof are substantially equivalent to the corresponding microscopic images or image sub-regions of the same sample that has been histochemically stained.

Abstract: A motor includes a stator having a winding that when selectively energized produces an electromagnetic field within a rotor cavity, and a rotor disposed within the rotor cavity of the stator and in electromagnetic communication with the winding and the electromagnetic field. The rotor includes a drive shaft, a rotor body that extends around the drive shaft and that defines a plurality of reluctance voids, and magnet inserts that are disposed within the reluctance voids. The magnet inserts occupy at least a portion of a space defined by the reluctance voids. The magnet inserts and the reluctance voids cooperate with the electromagnetic field to produce an electromagnetic torque.

Abstract: A method for generating a complexity-reduced time model of a distributed system. The method includes receiving time data, receiving a control path model and modeling the received time data as a stochastic process in order to obtain an original stochastic process. The method furthermore includes decomposing the original stochastic process into a plurality of modes of the original stochastic process, in order to obtain an approximation of the original stochastic process. The method includes performing a sensitivity analysis using the control path model and the approximation. The method furthermore includes selecting a first subset of modes of the approximation on the basis of the comparison and/or a default value, and outputting a complexity-reduced time model on the basis of the first subset of the modes.

Abstract: A lighting system for a watercraft includes a level sensor generating a level signal corresponding to a level of the watercraft. The system also includes a light source. The system also includes a plurality of elements optically coupled to the light source. The system also includes a controller coupled to the level sensor and the light source, said controller controlling the light source to illuminate selected elements less than all the elements to form a beam pattern.

Abstract: A time-of-flight (TOF) system includes a driver driving a VCSEL-array to emit light, a reference array receiving a reference light-signal, and a return array receiving emitted light that reflects off a target. Reference readout circuitry reads out the reference array. Return readout circuitry reads out the return array. A first buffer-driver buffers a base timing-reference to produce a first timing-reference. A second buffer-driver buffers the first timing-reference to produce a second timing-reference. Calibration circuitry takes a first TOF-measurement using the return readout circuitry when it is clocked by the first timing-reference, takes a second time of flight measurement using the return readout circuitry when it is clocked by the second timing-reference, and compensates for an offset between TOF taken by the return readout circuitry and the reference readout circuitry during normal operation based on the first and second TOF-measurements.

Abstract: The present invention relates to control system (1) for controlling a charging process of an implantable medical device, IMD, for a patient, the control system (1) comprising: means for determining a temperature (10) of a tissue of a patient; a control unit (20) configured to determine a cumulative thermal dose of the patient based on the determined temperature; wherein the control unit (20) is configured to continue, after an interruption of the charging process and upon resumption of the charging process, the determination of the cumulative thermal dose based on one or more predefined conditions, wherein the control unit (20) is configured to reset the determined cumulative thermal dose when a time span from interruption is greater than a time limit and/or when a measured temperature is lower than a temperature limit. The present invention is further directed to a system comprising such a control system, to a method and a corresponding computer program.