Abstract: A suture device for use in combination with a delivery system including a lumen extending through the delivery system includes a needle usable to carry a suture, a distal shuttle configured to releasably secure the needle, a sleeve disposable over the distal shuttle, the distal shuttle movable relative to the sleeve between a locked position in which the needle is locked to the distal shuttle and an unlocked position in which the needle is releasable from the distal shuttle. The suture device includes a distal assembly including an elongate tool guide movable between a deployment configuration in which the elongate tool guide is substantially parallel with the distal assembly and a working configuration in which the elongate tool guide curves away from the distal assembly.

Abstract: A medical system includes a plurality of tubes configured to be arranged about a periphery of an insertion device. A lumen of each of the plurality of tubes is configured to receive a medical device. Each of the tubes is configured to be coupled to the periphery of the insertion device and is moveable from a collapsed configuration adjacent the periphery of the insertion device to an expanded configuration further radially outward of the periphery of the insertion device as compared to the collapsed configuration.

Abstract: Medical devices for cinching and cutting one or more suture, and methods for making and using such devices are disclosed. An example medical device may include a shaft, a sleeve attached to the shaft, cutter slidable within the sleeve, a cinch sleeve releasably coupled to the sleeve, and a cinch member. An elongated inner shaft may extend through and be longitudinally movable within the elongated shaft, sleeve, cutter, cinch sleeve, and cinch member. The inner shaft may be actuated to cinch and cut one or more suture disposed within the device.

Abstract: A tissue grasping device for use with an endoscope may include a sheath, a control wire slidably disposed within the sheath, and a helical coil disposed over and attached to the control wire. The helical coil may include a proximal region in which adjacent windings are in contact, and a distal region in which adjacent windings are spaced apart. The helical coil may have a sharpened distal tip.

Abstract: A device includes a handle having a trigger in combination with a distal portion, the distal portion including a rigid elongated hollow member which receives tissue therein and a plunger fitted with and configured to slide longitudinally within the hollow member to induce suction at a distal end of the hollow member as the plunger is moved proximally within the hollow member. The trigger is hingedly coupled to the plunger so that pulling the trigger slides the plunger proximally with respect to the hollow member to generate suction to draw the tissue into the distal end of the hollow member. The device further includes a tissue treatment mechanism for encircling the tissue received at the distal end of the hollow member.

Abstract: A device may include an elongated housing formed of an optically transparent material, the housing extending from a proximal end to a distal end and including a lateral wall extending from the proximal end to a distal tip of the housing, the housing defining a lumen extending into the housing from a proximal opening in the proximal end of the housing. The device also may include a first port extending through the lateral wall of the housing to open the lumen of the housing to an exterior of the housing, the first port being sized and shaped to receive therein a target portion of tissue to be inspected and/or treated.

Abstract: The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to tissue clip devices and related systems and methods. In an embodiment, a tissue clip may include a grasper including jaws at a first end, and a spring portion at a second end, and a longitudinal axis extending along a length of the grasper from the first end to the second end, wherein the spring portion is configured to bias the jaws toward each other. A wedge may be slidably disposed between the jaws such that an apex of the wedge is oriented toward the spring portion. A filament may be coupled to the wedge at a first end of the filament and may extend through a channel of the spring portion of the grasper to a second end of the filament.

Abstract: A clipping device includes a capsule and a pair of clip arms, proximal ends of the clip arms slidably received within the channel of the capsule such that the clip arms are movable relative to the capsule between an open configuration and a closed configuration. The clipping device also includes a pair of jaws, each of the jaws pivotally coupled to a corresponding one of the clip arms and movable relative to the clip arms between an insertion configuration, in which longitudinal axes of the pair of jaws are substantially aligned with longitudinal axes of the clip arms, and a tissue-receiving configuration, in which the longitudinal axes of the pair of jaws extend transverse to the longitudinal axes of the clip arms, the pair of jaws movable toward the tissue-receiving configuration when the pair of clip arms are in the open configuration.

Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include a body extending along an axis and a distal cap positioned distally of the body and coupled to a shaft extending along the axis. The body and the distal cap may be movable relative to each other. An anchoring mechanism may be capable of engaging the body and the distal cap proximate a selected tissue for resection in the body lumen. A tissue capture device may be deployable from the tissue resection device such that a selected tissue for resection is securable by the tissue capture device. The tissue resection device may further include a tissue resecting device for resecting the selected tissue for resection.

Abstract: Exemplary embodiments of the present disclosure relate to devices, systems, and methods for tissue resection in a body lumen of a patient, and may include an endoscope and a backstop delivery device extendable through the endoscope. The backstop delivery device may deliver a backstop to a location of selected tissue for resection. A backstop may include a covering being deployable in a patient. The covering may have one or more anchoring mechanisms disposed on an edge of the covering. A tissue resecting device may be extendable through the endoscope for resecting the selected tissue for resection. The covering may be deployable to an outer surface of the body lumen, such that the anchoring mechanism may secure the covering to the outer surface of the body lumen and the covering may expand to cover the selected tissue for resection.