Patents by Inventor Kevin L. Bicker

Kevin L. Bicker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11369586
    Abstract: Described herein are antifungal peptoids, the development and characterization of the antifungal peptoids, methods of making the antifungal peptoids, and methods of using the antifungal peptoids. In some embodiments, the antifungal peptoids may be administered to a subject infected with or at risk of being infected with pathogenic fungi including, for example Cryptococcus spp. In some embodiments, the Cryptococcus spp. may include C. neoformans or C. gattii or both.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: June 28, 2022
    Assignee: Middle Tennessee State University
    Inventors: Kevin L. Bicker, Madyson P. Middleton, Scott A. Armstrong
  • Publication number: 20210115491
    Abstract: A solid supported branched linker assay system, including an alpha compound and a beta compounds reversibly tethered to a solid support; a branched linker coupled to the solid support that tethers the alpha and beta compounds to the solid support; the branched linker having two cleavable linkers that are chemically distinct from one another, wherein a first chemically distinct linker tethers the ? compound to the branched linker and a second chemically distinct linker tethers the ? compound to the branched linker; and at least two means for cleaving the chemically distinct linkers, wherein a first cleavage means is configured to selectively cleave a first chemically distinct linker and a second cleavage means is configured to selectively cleave a second chemically distinct linker.
    Type: Application
    Filed: October 29, 2020
    Publication date: April 22, 2021
    Applicant: Middle Tennessee State University
    Inventors: Kevin L. Bicker, Kevin J. Fisher, Ashley E. Corson
  • Patent number: 10851400
    Abstract: A solid supported branched linker assay system, including an alpha compound and a beta compounds reversibly tethered to a solid support; a branched linker coupled to the solid support that tethers the alpha and beta compounds to the solid support; the branched linker having two cleavable linkers that are chemically distinct from one another, wherein a first chemically distinct linker tethers the ? compound to the branched linker and a second chemically distinct linker tethers the ? compound to the branched linker; and at least two means for cleaving the chemically distinct linkers, wherein a first cleavage means is configured to selectively cleave a first chemically distinct linker and a second cleavage means is configured to selectively cleave a second chemically distinct linker.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: December 1, 2020
    Inventors: Kevin L. Bicker, Kevin J. Fisher, Ashley E. Corson
  • Publication number: 20200188354
    Abstract: Described herein are antifungal peptoids, the development and characterization of the antifungal peptoids, methods of making the antifungal peptoids, and methods of using the antifungal peptoids. In some embodiments, the antifungal peptoids may be administered to a subject infected with or at risk of being infected with pathogenic fungi including, for example Cryptococcus spp. In some embodiments, the Cryptococcus spp. may include C. neoformans or C. gattii or both.
    Type: Application
    Filed: December 18, 2019
    Publication date: June 18, 2020
    Inventors: Kevin L. Bicker, Madyson P. Middleton, Scott A. Armstrong
  • Patent number: 10155676
    Abstract: A process for extracting a surfactant from a mixture using a boronic acid modified material.
    Type: Grant
    Filed: August 26, 2016
    Date of Patent: December 18, 2018
    Inventors: Kevin L Bicker, Robert William Tilford
  • Patent number: 9921225
    Abstract: Novel phenyl-glyoxal based anti-citrulline probes and methods of synthesis are provided. Methods of use, such as, the development of methods for monitoring substrate citrullination over time; for identifying citrullinated proteins from cells are described.
    Type: Grant
    Filed: May 20, 2016
    Date of Patent: March 20, 2018
    Assignee: The Scripps Research Institute
    Inventors: Paul R. Thompson, Kevin L. Bicker, Venkataraman Subramanian
  • Publication number: 20170268032
    Abstract: A solid supported branched linker assay system, including an alpha compound and a beta compounds reversibly tethered to a solid support; a branched linker coupled to the solid support that tethers the alpha and beta compounds to the solid support; the branched linker having two cleavable linkers that are chemically distinct from one another, wherein a first chemically distinct linker tethers the ? compound to the branched linker and a second chemically distinct linker tethers the ? compound to the branched linker; and at least two means for cleaving the chemically distinct linkers, wherein a first cleavage means is configured to selectively cleave a first chemically distinct linker and a second cleavage means is configured to selectively cleave a second chemically distinct linker.
    Type: Application
    Filed: March 20, 2017
    Publication date: September 21, 2017
    Applicant: Middle Tennessee State University
    Inventors: Kevin L. Bicker, Kevin J. Fisher, Ashley E. Corson
  • Publication number: 20170057840
    Abstract: A process for extracting a surfactant from a mixture using a boronic acid modified material.
    Type: Application
    Filed: August 26, 2016
    Publication date: March 2, 2017
    Inventors: Kevin L. Bicker, Robert William Tilford
  • Publication number: 20160258961
    Abstract: Novel phenyl-glyoxal based anti-citrulline probes and methods of synthesis are provided. Methods of use, such as, the development of methods for monitoring substrate citrullination over time; for identifying citrullinated proteins from cells are described.
    Type: Application
    Filed: May 20, 2016
    Publication date: September 8, 2016
    Inventors: Paul R. Thompson, Kevin L. Bicker, Venkataraman Subramanian
  • Patent number: 9347948
    Abstract: Novel phenyl-glyoxal based anti-citrulline probes and methods of synthesis are provided. Methods of use, such as, the development of methods for monitoring substrate citrullination over time; for identifying citrullinated proteins from cells are described.
    Type: Grant
    Filed: June 4, 2013
    Date of Patent: May 24, 2016
    Assignee: The Scripps Research Institute
    Inventors: Paul R. Thompson, Kevin L. Bicker, Venkataraman Subramanian
  • Publication number: 20150148259
    Abstract: Novel phenyl-glyoxal based anti-citrulline probes and methods of synthesis are provided. Methods of use, such as, the development of methods for monitoring substrate citrullination over time; for identifying citrullinated proteins from cells are described.
    Type: Application
    Filed: June 4, 2013
    Publication date: May 28, 2015
    Inventors: Paul R. Thompson, Kevin L. Bicker, Venkataraman Subramanian