Patents by Inventor Kevin L. Moore
Kevin L. Moore has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240076066Abstract: A fixed-wing unmanned aerial vehicle (UAV) includes a propeller gimbal operably coupled to the body of the UAV at the forward end and the propeller gimbal is configured to pivot the propeller about a gimbal pivot axis to change a propeller angle. A controller of the UAV may be configured to control an attitude of flight of the UAV by controlling operation of the motor, the propeller gimbal, and the control surface assembly. The controller may be further configured to determine in-flight trajectory modifications that may require high maneuverability via high angle-of-attack attitudes of flight that are implemented via the propeller gimbal and trajectories determined from a dynamics model of the fixed-wing UAV.Type: ApplicationFiled: July 6, 2023Publication date: March 7, 2024Inventors: Joseph L. Moore, Max R. Basescu, Adam C. Polevoy, Bryanna Y. Yeh, Luca Scheuer, Kevin C. Wolfe
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Patent number: 10734118Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: GrantFiled: May 12, 2017Date of Patent: August 4, 2020Assignee: Washington UniversityInventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Publication number: 20170249441Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: ApplicationFiled: May 12, 2017Publication date: August 31, 2017Inventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Patent number: 9679110Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: GrantFiled: June 1, 2012Date of Patent: June 13, 2017Assignee: Washington UniversityInventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Publication number: 20120310615Abstract: Embodiments develop a predictive dose-volume relationships for a radiation therapy treatment is provided. A system includes a memory area for storing data corresponding to a plurality of patients, wherein the data comprises a three-dimensional representation of the planning target volume and one or more organs-at-risk. The data further comprises an amount of radiation delivered to the planning target volume and the one or more organs-at-risk. The system further includes one or more processors programmed to access, from the memory area, the data and to develop a model that predicts dose-volume relationships using the three-dimensional representations of the planning target volume and the one or more organs-at-risk. The model is being derived from correlations between dose-volume relationships and calculated minimum distance vectors between discrete volume elements of the one or more organs-at-risk and a boundary surface of the planning target volume.Type: ApplicationFiled: June 1, 2012Publication date: December 6, 2012Inventors: Kevin L. Moore, Sasa Mutic, Ryan Scott Brame, Lindsey Appenzoller
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Patent number: 7575885Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: GrantFiled: January 3, 2008Date of Patent: August 18, 2009Assignee: Siwa Biotech CorporationInventor: Kevin L Moore
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Publication number: 20090042738Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: ApplicationFiled: January 3, 2008Publication date: February 12, 2009Inventor: Kevin L. Moore
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Patent number: 7316912Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: GrantFiled: January 20, 2006Date of Patent: January 8, 2008Assignee: Siwa Biotech CorporationInventor: Kevin L. Moore
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Patent number: 7309008Abstract: The invention facilitates the computation of expected approval rates based on historic transaction data relating to transaction classes, approved transactions and declined transactions. The invention provides a system and method by which a program administrator for a company may model varying client-imposed limit scenarios in order to determine one or more optimal monthly and/or transactional spending limits. Further, the present invention provides a means for setting varying monthly and/or transaction spending limits for purchases from any number of industries. Providing card members with information regarding optimal spending limits reduces the occurrences of declined credit transactions.Type: GrantFiled: October 23, 2006Date of Patent: December 18, 2007Assignee: American Express Travel Related Services Company, Inc.Inventors: Gordon Emory Anderson, Catherine J Campanaro, David S Connelly, Sanjay Madaan, Kevin L Moore, Sangarsh Nigam, Yulona Sue Wong
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Patent number: 7143936Abstract: The invention facilitates the computation of expected approval rates based on historic transaction data relating to transaction classes, approved transactions and declined transactions. The invention provides a system and method by which a program administrator for a company may model varying client-imposed limit scenarios in order to determine one or more optimal monthly and/or transactional spending limits. Further, the present invention provides a means for setting varying monthly and/or transaction spending limits for purchases from any number of industries. Providing card members with information regarding optimal spending limits reduces the occurrences of declined credit transactions.Type: GrantFiled: February 9, 2005Date of Patent: December 5, 2006Assignee: American Express Travel Related Services Company, Inc.Inventors: Gordon Emory Anderson, Catherine J. Campanaro, David S. Connelly, Sanjay Madaan, Kevin L. Moore, Sangarsh Nigam, Yulona Sue Wong
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Patent number: 7029890Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: GrantFiled: July 22, 2002Date of Patent: April 18, 2006Assignee: Siwa Biotech CorporationInventor: Kevin L. Moore
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Publication number: 20040132105Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells, and to treat various conditions involving leukocyte binding via P-selectin glycoprotein ligand.Type: ApplicationFiled: December 17, 2003Publication date: July 8, 2004Inventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver
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Patent number: 6713283Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding the enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: GrantFiled: April 11, 2003Date of Patent: March 30, 2004Assignee: The Board of Regents of the University of OklahomaInventor: Kevin L. Moore
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Patent number: 6667036Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells, and to treat various conditions involving leukocyte binding via P-selectin glycoprotein ligand.Type: GrantFiled: November 18, 2002Date of Patent: December 23, 2003Assignee: The Board of Regents of the University of OklahomaInventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver
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Publication number: 20030170849Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosylprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: ApplicationFiled: April 11, 2003Publication date: September 11, 2003Inventor: Kevin L. Moore
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Patent number: 6605455Abstract: Tyrosylprotein sulfotransferases and nucleic acids encoding the tyrosyiprotein sulfotransferases are described. Dual isotopes of the enzyme and of the nucleic acids encoding said enzymes have been identified in human, mouse and C. elegans. The polypeptides and polynucleotides exhibit a wide range of homologies. The polynucleotides can be used to transform or transfect host cells for producing substantially pure forms of the enzyme, or for use in an expression system for post-translational tyrosine sulfation of proteins or peptides produced within the expression system. The enzymes can be used to sulfate peptides or proteins requiring sulfation.Type: GrantFiled: February 16, 2001Date of Patent: August 12, 2003Assignee: The Board of Regsnts of the University of OklahomaInventor: Kevin L. Moore
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Publication number: 20030072755Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells, and to treat various conditions involving leukocyte binding via P-selectin glycoprotein ligand.Type: ApplicationFiled: November 18, 2002Publication date: April 17, 2003Inventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver
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Patent number: 6506382Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells.Type: GrantFiled: October 29, 2001Date of Patent: January 14, 2003Assignee: The Board of Regents of the University of OklahomaInventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver
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Publication number: 20020122796Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells.Type: ApplicationFiled: October 29, 2001Publication date: September 5, 2002Inventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver
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Patent number: 6309639Abstract: P-selectin has been demonstrated to bind primarily to a single major glycoprotein ligand on neutrophils and HL-60 cells, when assessed by blotting assays and by affinity chromatography of [3H]glucosamine-labeled HL-60 cell extracts on immobilized P-selectin. This molecule was characterized and distinguished from other well-characterized neutrophil membrane proteins with similar apparent molecular mass. The purified ligand, or fragments thereof (including both the carbohydrate and protein components), or antibodies to the ligand, or fragments thereof, can be used as inhibitors of binding of P-selectin to cells.Type: GrantFiled: August 9, 2000Date of Patent: October 30, 2001Assignee: The Board of Regents of the University of OklahomaInventors: Richard D. Cummings, Kevin L. Moore, Rodger P. McEver