Abstract: Embodiments provided herein, provide for variant IgG Fc polypeptides, dimeric molecules, pharmaceutical compositions, and methods that can be used to target at cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity and a variant Fc molecule, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as IgG mediated disorders.

Abstract: Methods and compounds for conferring kidney-specific immune privilege.

Abstract: Microscopy probes that include luminescent metal binding proteins and peptides and analogs thereof that are configured to be used in electron microscopy and methods of performing light and electron microscopy using the microscopy probes of the present technology.

Abstract: Methods and polypeptides for conferring site-specific or local immune privilege.

Abstract: Embodiments provided herein, provide for polypeptides, pharmaceutical compositions, and methods that can be used, for example, to target at least two types of cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity and a variant Fc molecule, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as IgG mediated disorders.

Abstract: Methods and compounds for conferring skin-specific immune privilege.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: Embodiments provided herein, provide for variant IgG Fc polypeptides, dimeric molecules, pharmaceutical compositions, and methods that can be used to target at cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: Embodiments provided herein, provide for polypeptides and molecules comprising a polypeptide having protease activity and a variant Fc molecule, pharmaceutical compositions comprising the same, and methods that can be used to treat disorders, such as IgG mediated disorders.

Abstract: Embodiments provided herein, provide for variant IgG Fc polypeptides, dimeric molecules, pharmaceutical compositions, and methods that can be used to target at cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: An example battery module includes a housing; a cell mounting plate mounted to the housing such that the housing and the cell mounting plate mounted thereto form an enclosure; a plurality of battery cells mounted and adhered to the cell mounting plate within the enclosure; a temperature sensing structure mounted within the enclosure and having one or more branches extending between respective battery cells of the plurality of battery cells; a current collector mounted to the plurality of battery cells, opposite the cell mounting plate; and a cover mounted to the housing such that a venting chamber is formed between the plurality of battery cells and an interior surface of the cover, wherein gas generated by the respective battery cells of the plurality of battery cells is provided to the venting chamber.

Abstract: An example battery module includes: a housing; a cell stack assembly mounted within the housing and comprising a plurality of cell stacks, each cell stack comprising a plurality of cells separated by respective thermal pads, wherein cell stacks of the plurality of cell stacks are separated by respective thermal barrier plates, wherein each cell of the plurality of cells comprises one or more cell tabs; a first compression plate disposed at a first end of the cell stack assembly; a second compression plate disposed at a second end of the cell stack assembly, such that the cell stack assembly is interposed and compressed between the first compression plate and the second compression plate; and a cell tab divider plate mounted to the cell stack assembly, wherein the cell tab divider plate comprises a plurality of slits that accommodate the one or more cell tabs of each cell therethrough.

Abstract: Methods and compounds for conferring site-specific or local immune privilege, such as to the skin.

Abstract: Embodiments provided herein, provide for variant IgG Fc polypeptides, dimeric molecules, pharmaceutical compositions, and methods that can be used to target at cells to modulate the activity of the same to treat disorders, such as autoimmune disorders or cancers.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: Herein is database query acceleration from dynamic discovery of whether contents of a persistent column can be stored in an accelerated representation in storage-side memory. In an embodiment, based on data type discovery, a storage server detects that column values in a persistent column have a particular data type. Based on storage-side metadata including a frequency of access of the persistent column as an offload input column for offload computation requests on a certain range of memory addresses, the storage server autonomously decides to generate and store, in storage-side memory in the storage server, an accelerated representation of the persistent column that is based on the particular data type. The storage server receives a request to perform an offload computation for the offload input column. Based on the accelerated representation of the persistent column, execution of the offload computation is accelerated.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.