Abstract: An implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ) containing at least one loop. The coiled marker is deployed to mark a tissue site in the body for subsequent surgery, and a magnetic detection system with a handheld probe excites the marker above or below the switching field required for bistable switching of the marker causing a harmonic response to be generated in a bistable or sub-bistable mode that allows the marker to be detected and localised.

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

Abstract: A method for detecting a marker in a body, comprising receiving an input signal from a probe, where the input signal is generated by a probe in response to detecting a marker signal from the marker; determining a marker proximity value based on the input signal, the marker proximity value corresponds to a distance between the probe and the marker; generating a feedback signal for output by a user interface device based on the marker proximity value, and outputting feedback signal, wherein range of the marker proximity value is divided into predetermined distance bands; and wherein at least one parameter of the feedback signal, or a rate of change of the at least one parameter of the feedback signal in relation to marker proximity value, is varied discontinuously at a boundary between at least two adjacent bands. The feedback signal may be an audio signal and/or a haptic signal.

Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Abstract: A hyperthermia implant 20 for hyperthermia treatment of tissue 30 of a human or animal body. The implant comprises at least one piece of a large Barkhausen jump material (LBJ) and a magnetic field may be applied to the implant to heat the surrounding tissue. The implant may also be deployed to mark a tissue site in the body for subsequent surgery, thereby providing a combined system for locating an implant and treating the surrounding area. The system includes a handheld probe 14 to excite the implant below the switching field for bistable switching causing a harmonic response to be generated in a sub-bistable mode that allows the implant to be detected and localised.

Abstract: An implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ) containing at least one loop. The coiled marker is deployed to mark a tissue site in the body for subsequent surgery, and a magnetic detection system with a handheld probe excites the marker above or below the switching field required for bistable switching of the marker causing a harmonic response to be generated in a bistable or sub-bistable mode that allows the marker to be detected and localised.

Abstract: An implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ) containing at least one loop. The coiled marker is deployed to mark a tissue site in the body for subsequent surgery, and a magnetic detection system with a handheld probe excites the marker above or below the switching field required for bistable switching of the marker causing a harmonic response to be generated in a bistable or sub-bistable mode that allows the marker to be detected and localised.

Abstract: An implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ) containing at least one loop. The coiled marker is deployed to mark a tissue site in the body for subsequent surgery, and a magnetic detection system with a handheld probe excites the marker above or below the switching field required for bistable switching of the marker causing a harmonic response to be generated in a bistable or sub-bistable mode that allows the marker to be detected and localised.

Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Abstract: A valve (100) for use in delivering a medical device comprises first and second ends and an hourglass shaped centre section defining an aperture (34) for accepting a guidewire. The application of torsion about the centre section closes the aperture to seal against the guidewire.

Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.

Abstract: A valve (100) for use in delivering a medical device comprises first and second ends and an hourglass shaped centre section defining an aperture (34) for accepting a guidewire. The application of torsion about the centre section closes the aperture to seal against the guidewire.

Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.

Abstract: A scaling factor for scaling an output of a first electrochemical cell, is determined in order to compensate for the effect on the output caused by an variation in value of a property of a working electrode of the first cell from a reference value of that property. A measured value for the property is obtained from a portion of material formed so as to have substantially the same value of the property as does the working electrode and the measured value is processed to generate the scaling factor.

Abstract: The invention concerns an electrochemical cell which, either alone or together which a substrate onto which it is placed, is in the form of a receptacle. The electrochemical cell contains a working electrode and a counter electrode, the working electrode being in a wall of the receptacle. At least one of the electrodes has at least one dimension of less than 50 ?m. The electrochemical cell is principally intended for use as a micro-electrode suitable for screening water, blood, urine or other biological or non-biological fluids.

Abstract: A method is provided for determining the concentration of an analyte in a sample which comprises: a) performing an electrochemical test comprising: (i) contacting the sample with an electrochemical cell comprising at least two electrodes; and (ii) obtaining at least one group of three or more measurements of an electrochemical parameter from the cell, wherein each measurement in each at least one group is obtained at a different time; b) deriving from said at least one group of three or more measurements a single value that is indicative of the time-dependent behavior of the measured parameter; c) comparing the single value indicative of the time-dependent behavior of the measured parameter with a pre-determined range of acceptable time-dependent behaviors; d) determining whether the test is acceptable based on the result of said comparison; e) optionally repeating the above-mentioned steps; and 0 determining the concentration of the analyte from the measurements obtained from the acceptable test or acceptabl