Abstract: A surgical system may include tiered-access features. The surgical system may be used to analyze at least a portion of a surgical field. Based on a control parameter, the system may scale up or down various capabilities, such as visualization processing, endocutter communication, endocutter algorithm updates, smart cartridge connectivity, smart motor control for circular stapler, smart energy control, cloud analytics, hub connectivity control, and/or hub visualization and control interactions. The control parameter may include system aspects such as processing capability or bandwidth for example and/or the identification of an appropriate service tier.

Abstract: A surgical system is disclosed including a surgical instrument and a control system. The surgical instrument comprises an end effector, a first drive system, and a second drive system. The control system is configured to detect the actuation of the first drive system of the surgical instrument, drive a first function of the end effector using the first drive system, monitor a first parameter associated with a first function, set a second parameter associated with a second function of the end effector based on the monitored first parameter, and drive the second function of the end effector using the second drive system.

Abstract: The present invention provides for compounds of formula (I) wherein R1, R2, R3, R4A, R4b, and R5, are as defined herein, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of CLL.

Abstract: A surgical stapling system includes an anvil, a blade, a motor and gear assembly, a motor power supply, and a motor controller. A method of controlling the motor includes receiving first and second data indicative of operations of the motor under first and second conditions, respectively, and adjusting a motor control signal based on a difference between the first and second data. Another method includes receiving initial manufacture motor and gear assembly data from a manufacture and operational data during an initial use of the system, and adjusting parameters of the control signal based on a difference between the manufacture data and the operational data. Another method includes controlling a pulse-width modulated (PWM) motor control signal, receiving data regarding an interaction between the blade and a tissue clamped by the anvil, and adjusting a frequency of the PWM signal based on the data related to the interaction.

Abstract: Methods, devices, and systems for controlling a tissue-treatment motion by a surgical instrument are disclosed.

Abstract: A surgical instrument system comprising a motor system and a control circuit is disclosed. The motor system comprises a motor and a drive train movable by the motor to actuate a firing member through a staple firing stroke. The control circuit is coupled to the motor, wherein, during the staple firing stroke, the control circuit is configured to perform a first sensory action to determine if a speed of the motor can be increased to a first target speed, monitor a result of the first sensory action, adjust a parameter of a subsequent sensory action based on the monitored result of the first sensory action, and perform the subsequent sensory action with the adjusted parameter.

Abstract: An apparatus includes an end effector, a motor, and a processing unit. The processing unit is configured to activate the motor to distally advance a firing member within a body of the end effector. The processing unit is further configured to detect an initiation condition. In response to detecting the initiation condition, the processing unit is configured to activate an algorithmic bumping mode. The bumping mode includes activating the motor to advance the firing member distally with a first plurality starting and stopping motions at a first rate and a first power level. The bumping mode further includes activating the motor to retract the firing member proximally with a second plurality of starting and stopping motions at a second rate and a second power level. The first rate is different than the second rate. The first power level is different than the second power level.

Abstract: A surgical instrument controls communication capabilities between the surgical instrument and a removeable component. The surgical instrument may determine parameters associated with the surgical instrument and the removable component. Based on the parameters, the surgical instrument determines a level or tier of communication between the surgical instrument and the removable component. The surgical instrument may determine to configure one or more of the following levels: one-way static communication with the component; two-way communication with the component; real-time two-way communication with the component; and communication with a surgical hub.

Abstract: A control device may obtain sensing data related to a paving material mat region laid by a screed assembly of a road paver. The control device may determine, based on the sensing data, a respective texture value and/or a respective height value associated with each portion of two or more portions of the paving material mat region. The control device may determine, based on the respective texture values and/or the respective height values of the paving material mat region, a finish value associated with the paving material mat region. The control device may cause, based on the finish value of the paving material mat region, one or more actions to be performed.

Abstract: A control device may obtain sensing data related to a paving material mat region laid by a screed assembly of a road paver. The control device may determine, based on the sensing data, a respective texture value and/or a respective height value associated with each portion of two or more portions of the paving material mat region. The control device may determine, based on the respective texture values and/or the respective height values of the paving material mat region, a finish value associated with the paving material mat region. The control device may cause, based on the finish value of the paving material mat region, one or more actions to be performed.

Abstract: A milling system for a milling machine operating on a ground surface is provided. The milling system includes an Unmanned Aerial Vehicle (UAV) communicably coupled to the milling machine. The UAV is configured to scan and penetrate a portion of the ground surface proximate to the milling machine along a first direction. The UAV is also configured to detect if an object is present beneath the portion of the ground surface. The UAV is further configured to transmit data associated with the object, if the object is detected beneath the portion of the ground surface. The milling system also includes a controller communicably coupled to the UAV and the milling machine. The controller is configured to receive the data associated with the object. The controller is also configured to control an operation of a rotor of the milling machine based on the received data.

Abstract: Free cyanide-containing wastewater is treated to destroy the free cyanide content thereof by the step of treating said water with sulfur in the form of polysulfide in an integrated process wherein thiocyanate is also eliminated to produce a non-hazardous wastewater effluent and treating the wastewater in a second step with cultures of bacteria of the genus Thiobacillus in combination with nitrifying bacteria which oxidize ammonia to nitrite to nitrate. The first step is preferably carried out in the presence of a cationic surfactant, preferably a quaternary cationic surfactant, as a catalyst.

Abstract: Free cyanide-containing wastewater is treated to destroy the free cyanide content thereof by the step of treating said water with sulfur in the form of polysulfide in an integrated process wherein thiocyanate is also eliminated to produce a non-hazardous wastewater effluent and treating the wastewater in a second step with cultures of bacteria of the genus Thiobacillus in combination with nitrifying bacteria which oxidize ammonia to nitrite and nitrite to nitrate. The first step is preferably carried out in the presence of added metallic zinc.