Abstract: A mixing device including a container defining a container cavity, the container including a bottom wall supporting a hollow shaft, the shaft supporting an impeller thereon such that the impeller is free to rotate about the shaft, the impeller including a central passageway therethrough for receiving the shaft, the container further including an elongated evacuation tube having a first end positioned within the passageway of the shaft and an opposed second end extending to a port of the container. Methods of using the mixing device to provide improved cell culture.

Abstract: A dual-filter dual-integrity test conduit assembly allows for in-situ testing of both filters with separate, duplicate systems for membrane integrity so that if the first tester filter fails, the second filter may be tested with a different, but identical method with its own gauges and nitrogen supply so as to further isolate malfunctions of the filter integrity test equipment as a cause for erroneous batch failures.

Abstract: The present invention relates to methods and devices for mixing the contents of a mixing container, the device including a container defining a container cavity, the container including a bottom wall supporting a hollow shaft, the shaft supporting an impeller thereon such that the impeller is free to rotate about the shaft, the impeller including a central passageway therethrough for receiving the shaft, the container further including an elongate evacuation tube having a first end positioned within the passageway of the shaft and an opposed second end extending to a port of the container.

Abstract: Asceptic transfer through a needle penetrating a septum is accomplished by inserting an elongate inner tube through the needle and delivering a product fluid through the inner tube. Inner tube is desirably made from a polymer such as PTFE and product fluid does not contact the needle.

Abstract: The present invention provides a radiation-shielding container for a radiopharmaceutical that allows or a product fluid to be dispensed from a base component thereof.

Abstract: A dual-filter dual-integrity test conduit assembly allows for in-situ testing of both filters with separate, duplicate systems for membrane integrity so that if the first tester filter fails, the second filter may be tested with a different, but identical method with its own gauges and nitrogen supply so as to further isolate malfunctions of the filter integrity test equipment as a cause for erroneous batch failures.

Abstract: A loader device, for dispensing implantation seeds from a seed magazine, comprising a body (3), seed magazine receiving and locating means (27), seed dispensing means (37) for ejecting seeds from a seed magazine, and a seed-transporting path (17) leading to a dispensing outlet (8), which loader device further comprises a spacer-transporting path (29, 31, 33, 35) for transporting spacers through the device to the dispensing outlet (8).

Abstract: The present invention relates to a loader device, for dispensing implantation seeds from a seed magazine and, optionally, a spacer magazine.

Abstract: A loader device, for dispensing implantation seeds from a seed magazine, comprising a body (3), seed magazine receiving and locating means (27,), seed dispensing means (37) for ejecting seeds from a seed magazine, and a seed-transporting path (17) leading to a dispensing outlet (8), which loader device further comprises a spacer-transporting path (29, 31, 33, 35) for transporting spacers through the device to the dispensing outlet (8).

Abstract: A loader device, for dispensing implantation seeds from a seed magazine, comprising a body (3), seed magazine receiving and locating means (27,), seed dispensing means (37) for ejecting seeds from a seed magazine, and a seed-transporting path (17) leading to a dispensing outlet (8), which loader device further comprises a spacer-transporting path (29, 31, 33, 35) for transporting spacers through the device to the dispensing outlet (8).