Patents by Inventor Kevin M. Hennessy

Kevin M. Hennessy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods, compositions, and kits for detecting protein aggregates
    Patent number: 8535878
    Abstract: The present teachings provide methods, compositions, and kits for detecting the presence of protein aggregates. In some embodiments, the protein aggregate is treated with a labeled precursor, and the labeled precursor is incorporated into the protein aggregate to form a labeled protein aggregate. The labeled protein aggregate is then measured, thus detecting the presence of the protein aggregate. In some embodiments, the labeled protein aggregate is detected by interaction of labeled precursors, for example by a proximity ligation assay.
    Type: Grant
    Filed: May 2, 2007
    Date of Patent: September 17, 2013
    Assignee: Applied Biosystems, LLC
    Inventors: David W. Ruff, Mark E. Shannon, Kenneth J. Livak, Karl J. Guegler, Kevin M. Hennessy
  • Products and methods for reducing dye artifacts
    Patent number: 7378260
    Abstract: The present invention provides products and methods of reducing dye artifacts from chain extension reactions.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: May 27, 2008
    Assignee: Applera Corporation
    Inventors: Michael P. Harrold, Kevin M. Hennessy, Aldrich N. K. Lau, Sean Matthew Desmond
  • Petal-array support for use with microplates
    Patent number: 6833238
    Abstract: Devices are provided which include supports upon which one or more ion-exchange materials can be disposed for purifying a sample. In various embodiments, the supports include a plurality of deformable members, for example, petal-shaped purification members, that provide binding sites for ion-exchange material and optionally biochemical species, chemicals, salts, or other materials. An apparatus and method are also provided for the insertion and removal of the purification members into respective wells of a multi-well microplate.
    Type: Grant
    Filed: April 14, 2003
    Date of Patent: December 21, 2004
    Assignee: Applera Corporation
    Inventors: Paul O. Ramstad, Michael P. Harrold, Kevin M. Hennessy, Aldrich N. K. Lau
  • Device and method for purification of nucleic acids
    Publication number: 20040016702
    Abstract: A device for purifying a sample is provided, and includes ion-exchange particles in contact with a substrate. The device can include size-exclusion material and an ion-exchange material.
    Type: Application
    Filed: August 11, 2003
    Publication date: January 29, 2004
    Applicant: Applera Corporation
    Inventors: Kevin M. Hennessy, Aldrich N.K. Lau, Michael P. Harrold
  • Petal-array support for use with microplates
    Publication number: 20030228706
    Abstract: Devices are provided which include supports upon which one or more ion-exchange materials can be disposed for purifying a sample. In various embodiments, the supports include a plurality of deformable members, for example, petal-shaped purification members, that provide binding sites for ion-exchange material and optionally biochemical species, chemicals, salts, or other materials. An apparatus and method are also provided for the insertion and removal of the purification members into respective wells of a multi-well microplate.
    Type: Application
    Filed: April 14, 2003
    Publication date: December 11, 2003
    Applicant: Applera Corporation
    Inventors: Paul O. Ramstad, Michael P. Harrold, Kevin M. Hennessy, Aldrich N.K. Lau