Abstract: An apparatus includes a body, a catheter, and an end effector. The catheter extends distally from the body and includes a lumen. The end effector includes at least one electrode. The end effector further includes at least one port in fluid communication with the lumen of the catheter such that the lumen is operable to communicate the fluid from a fluid source to the at least one port. The end effector further includes at least one flexible sleeve positioned over the at least one port, the at least one flexible sleeve being configured to transition between a closed state in which the at least one flexible sleeve prevents the fluid from exiting the at least one port, and an open state in which the at least one flexible sleeve permits the fluid to exit the at least one port.

Abstract: A delivery sheath to catheter coupler includes a cylindrical shaft and a coupling member. The cylindrical shaft extends along an axis and is configured for longitudinal alignment with an insertion port of a catheter delivery sheath. The cylindrical shaft includes a proximal end, a distal end, and a lumen extending from the proximal end to the distal end along the axis. The lumen is sized to receive an end effector of a catheter. The coupling member is attached to the cylindrical shaft and is configured for selective securement to the catheter delivery sheath. The coupling member is configured to align the axis of the lumen with a longitudinal axis of the insertion port when the coupling member is selectively secured to the catheter delivery sheath.

Abstract: Disclosed is a cartridge-based detection system to prepare an injected sample to be investigated for determination of a microbial pathogen or another analyte of interest using a detector features a field-safe cartridge. The system features a plurality of reagent chambers located within the cartridge. The system features a rotating cylindrical dial that facilitates a sequential introduction of various fluids contained in each reagent chamber into the dial whereby the fluid washes internally for contact therein. A dial channel is located through the dial. A dual window region of interrogation is centrally located in the dial. The dial is pivoted into position to fluidly connect each mated anterior and posterior reagent chamber via the dial channel. Methods of used are also disclosed.

Abstract: Disclosed is a cartridge-based detection system to prepare an injected sample to be investigated for determination of a microbial pathogen or another analyte of interest using a detector features a field-safe cartridge. The system features a plurality of reagent chambers located within the cartridge. The system features a rotating cylindrical dial that facilitates a sequential introduction of various fluids contained in each reagent chamber into the dial whereby the fluid washes internally for contact therein. A dial channel is located through the dial. A dual window region of interrogation is centrally located in the dial. The dial is pivoted into position to fluidly connect each mated anterior and posterior reagent chamber via the dial channel. Methods of used are also disclosed.