Abstract: A glaucoma shunt device is provided for draining a biological fluid from an eye. The glaucoma shunt device includes a primary tube, a secondary tube, and a shunt body. The primary tube has a primary proximal end, a primary distal end, and a primary conduit extending therebetween. The secondary tube has a secondary proximal end, a secondary distal end, and a secondary conduit extending therebetween. The secondary tube is at least partially inserted through the primary conduit via the primary distal end. The secondary tube defines a flow resistance of the primary and secondary tubes. The shunt body has a reservoir therein and is integrated with the primary tube near the primary distal end such that the primary and secondary conduits are fluidly coupled with the reservoir.

Abstract: Drainage device for draining a biological fluid from an eye to a tissue external to the eye, as well as methods of forming the drainage device and treating glaucoma using the drainage device, are disclosed. The drainage device is implantable at least in part within a tissue of the eye and includes a collapsible body portion defining a reservoir, and a conduit having a first end fluidly coupled with the reservoir and a second end insertable into the eye to facilitate a drainage of the biological fluid into the conduit. When collapsed, the body portion includes a deformation from a first planar state to a second nonplanar state, where the second nonplanar state may be a folded, deformed, bent, or crumpled state.

Abstract: Glaucoma shunts for draining fluid from an eye to surrounding tissue and being implantable within eye tissue, the shunts include a shunt body formed from microporous materials arranged to form a reservoir within the shunt body, and a conduit having a proximal end in fluid communication with the reservoir and an opposing distal end, the distal end being insertable into the eye to facilitate drainage of fluid into the conduit via the distal end, wherein the conduit and the reservoir together define a flow passage along which drainage of fluid flows through the conduit, to the reservoir, and into surrounding tissue via the microporous material, wherein the flow passage presents a variable flow resistance along the conduit that has a plurality of sequential flow resistances with first and second flow resistances defined therein such that the first flow resistance is different from the second flow resistance.

Abstract: A glaucoma shunt for draining a fluid from an eye to a tissue surrounding the eye, the glaucoma shunt being implantable within tissue of the eye, the glaucoma shunt includes a shunt body that is formed from a microporous material that is arranged so as to form a reservoir within the shunt body; and a conduit in fluid communication with the reservoir, the conduit being insertable into the eye such that the fluid at a distal end of the conduit is allowed to flow through the conduit and accumulate within the reservoir, wherein the microporous material transitions from a hydrophobic state to a hydrophilic state as the fluid that is accumulated in the reservoir diffuses to the tissue surrounding the eye through the microporous material so as to provide a variable flow resistance as the microporous material transitions from the hydrophobic state to the hydrophilic state.