Abstract: An ultra wide band-pass, absorptive band-reject filter has a pair of quadrature hybrid couplers cascaded and coupled by a phase shifting element and a matched pair of band-reject filters in two parallel paths. The matched pair of band-reject filters each rejects signals in a desired reject frequency band. The quadrature hybrid couplers each have an insertion loss amplitude crossover for signals propagated to terminals across the coupler that coincides with the reject frequency band. The phase shifting element is configured to have a phase shift of 180 degrees at frequencies in the reject frequency band. In a preferred embodiment, the pair of quadrature hybrid couplers are identical in performance and the band-reject filters are identical in performance with respect to a center frequency fn of the reject frequency band. The absorptive band-reject filter thereby provides an absorptive rejection response in the reject frequency band while a very wide pass-band frequency range is maintained.

Abstract: The invention relates to a method of modulating neuronal function by modulating the cytoplasmic level in a neuron of an intron-containing mRNA. The methods are useful in diagnostic, research and therapeutic applications.

Abstract: The present invention relates to methods of synaptic network remodeling by means of extranuclear RNA splicing. The present invention also provides methods of extranuclear RNA splicing, and methods of protein translation based on extranuclear RNA splicing.

Abstract: An ultra wide band-pass, absorptive band-reject filter has a pair of quadrature hybrid couplers cascaded and coupled by a phase shifting element and a matched pair of band-reject filters in two parallel paths. The matched pair of band-reject filters each rejects signals in a desired reject frequency band. The quadrature hybrid couplers each have an insertion loss amplitude crossover for signals propagated to terminals across the coupler that coincides with the reject frequency band. The phase shifting element is configured to have a phase shift of 180 degrees at frequencies in the reject frequency band. In a preferred embodiment, the pair of quadrature hybrid couplers are identical in performance and the band-reject filters are identical in performance with respect to a center frequency fn of the reject frequency band. The absorptive band-reject filter thereby provides an absorptive rejection response in the reject frequency band while a very wide pass-band frequency range is maintained.

Abstract: An electronically tuned, absorptive, low-loss notch filter with high RF power handling capability is obtained using a four-port quadrature hybrid coupler connected to a matched pair of band pass resonator devices and resistive terminations. The notch filter design uses series-only tuning elements for the band pass resonator devices to raise the RF power handling of the band pass resonators far above conventional techniques while also being tunable at high speeds. The notch filter architecture and method can be used for interference cancellation in a wide range of wireless technologies, such as cellular phone, wireless routers, hand-held radios, satellite communications, and any other environments where there are a number of wireless technologies in close signal proximity.

Abstract: The present invention discloses methods of removing unwanted fluorescence from a sample by photobleaching said sample to enhance detection of proteins and fragments thereof, polynucleotides and fragments thereof, and biomolecules and fragments thereof in a sample by contacting said proteins, polynucleotides and biomolecules with a fluorescent reporter, wherein said fluorescent reported comprises a fluorescent semiconductor crystal or SCN, wherein said SCN further comprises a targeting moiety.

Abstract: The invention relates to a method of modulating neuronal function by modulating the cytoplasmic level in a neuron of an intron-containing mRNA. The methods are useful in diagnostic, research and therapeutic applications.

Abstract: The present invention relates to methods of synaptic network remodeling by means of extranuclear RNA splicing. The present invention also provides methods of extranuclear RNA splicing, and methods of protein translation based on extranuclear RNA splicing.

Abstract: An electronically tuned, absorptive, low-loss notch filter with high RF power handling capability is obtained using a four-port quadrature hybrid coupler connected to a matched pair of band pass resonator devices and resistive terminations. The notch filter design uses series-only tuning elements for the band pass resonator devices to raise the RF power handling of the band pass resonators far above conventional techniques while also being tunable at high speeds. The notch filter architecture and method can be used for interference cancellation in a wide range of wireless technologies, such as cellular phone, wireless routers, hand-held radios, satellite communications, and any other environments where there are a number of wireless technologies in close signal proximity.

Abstract: A wide bandwidth, high power amplifier system for amplifying a signal in a radio frequency (RF) system in a specific bandwidth within the frequency range from 1 MHz to 100 GHz. The system includes a number of amplifier modules and an equal number of input transformers connected in series, with each input transformer providing an input signal to one amplifier module. It also includes an equal number of output transformers connected in series with each output transformer receiving an input signal from one amplifier module. The series of input transformers, the series of output transformers and the amplifier modules each provide an impedance matched approximately to the impedance of the RF system.

Abstract: The present invention relates to methods of synaptic network remodeling by means of extranuclear RNA splicing. The present invention also provides methods of extranuclear RNA splicing, and methods of protein translation based on extranuclear RNA splicing.

Abstract: A wide bandwidth, high power amplifier system for amplifying a signal in a radio frequency (RF) system in a specific bandwidth within the frequency range from 1 MHz to 100 GHz. The system includes a number of amplifier modules and an equal number of input transformers connected in series, with each input transformer providing an input signal to one amplifier module. It also includes an equal number of output transformers connected in series with each output transformer receiving an input signal from one amplifier module. The series of input transformers, the series of output transformers and the amplifier modules each provide an impedance matched approximately to the impedance of the RF system.

Abstract: Disclosed is a system and circuit for a multi-channel optoelectronic device driver. The system and circuit include a differential buffer amplifier, an output driver amplifier, a dedicated voltage regulator, a load compensation circuit, a wave shaping circuit and a laser fault detection circuit. In a multi-channel configuration, each channel has a dedicated voltage regulator such that each channel provides a channel-specific drive signal.

Abstract: Disclosed is a system and circuit for a multi-channel optoelectronic device driver. The system and circuit include a differential buffer amplifier, an output driver amplifier, a dedicated voltage regulator, a load compensation circuit, a wave shaping circuit and a laser fault detection circuit. In a multi-channel configuration, each channel has a dedicated voltage regulator such that each channel provides a channel-specific drive signal.

Abstract: A method of identifying neurite cDNA clones by determining and comparing mRNA expression in selected neurites is provided. cDNA clones identified by this method are also provided. In addition, methods of profiling mRNA expression and diagnosing and treating conditions associated with a pattern of mRNA expression by determining an mRNA expression profile in selected cells are provided.

Abstract: A method of identifying neurite cDNA clones by determining and comparing mRNA expression in selected neurites is provided. cDNA clones identified by this method are also provided. In addition, methods of profiling mRNA expression and diagnosing and treating conditions associated with a pattern of mRNA expression by determining an mRNA expression profile are provided.