Patents by Inventor Kevin N. Dalby

Kevin N. Dalby has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
    Publication number: 20250136580
    Abstract: The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).
    Type: Application
    Filed: November 12, 2024
    Publication date: May 1, 2025
    Inventors: Kevin N. Dalby, Ramakrishna Edupuganti, Juliana Taliaferro, Ju Hyeon Lee
  • INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
    Publication number: 20210317107
    Abstract: The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).
    Type: Application
    Filed: April 19, 2021
    Publication date: October 14, 2021
    Inventors: Kevin N. Dalby, Ramakrishna Edupuganti, Juliana Taliaferro, Ju Hyeon Lee
  • Indolinone derivatives as inhibitors of maternal embryonic leucine zipper kinase
    Patent number: 10981896
    Abstract: The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: April 20, 2021
    Assignee: BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Kevin N. Dalby, Ramakrishna Edupuganti, Juliana Taliaferro, Ju Hyeon Lee
  • INDOLINONE DERIVATIVES AS INHIBITORS OF MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE
    Publication number: 20200010455
    Abstract: The present disclosure relates to indolinone compounds, compositions, and methods for the inhibition of maternal embryonic leucine zipper kinase (MELK). The present disclosure further relates to indolinone compounds, compositions, and methods for the treatment or prevention of a cancer (for example, triple negative breast cancer).
    Type: Application
    Filed: March 2, 2018
    Publication date: January 9, 2020
    Inventors: Kevin N. Dalby, Ramakrishna Edupuganti, Juliana Taliaferro, Juhyeon Lee
  • Novel Compositions and Methods for Treating Cancer
    Publication number: 20150306077
    Abstract: Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.
    Type: Application
    Filed: April 28, 2015
    Publication date: October 29, 2015
    Inventors: Bulent Ozpolat, Gabriel Lopez-Berestein, Kevin N. Dalby, Jiney Jose
  • Compositions and methods for treating cancer
    Patent number: 9073851
    Abstract: Provided herein are methods and compositions inter alia for treating diseases, including hyperproliferative diseases, migraine headaches, and depression.
    Type: Grant
    Filed: October 26, 2012
    Date of Patent: July 7, 2015
    Assignee: Board of Regents, the University of Texas System
    Inventors: Bulent Ozpolat, Gabriel Lopez-Berestein, Kevin N. Dalby, Jiney Jose