Patents by Inventor Kevin Paul Raisch

Kevin Paul Raisch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human anti-epidermal growth factor receptor single-chain antibodies
    Patent number: 7045127
    Abstract: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal growth factor receptor and the truncated and/or mutated epidermal growth factor receptor on human cells. These anti-EGFR-scFvs are useful as therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: November 6, 2003
    Date of Patent: May 16, 2006
    Assignee: The UAB Research Foundation
    Inventors: Kevin Paul Raisch, David T. Curiel, James Alan Bonner
  • Human anti-epidermal growth factor receptor single-chain antibodies
    Publication number: 20040071698
    Abstract: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal growth factor receptor and the truncated and/or mutated epidermal growth factor receptor on human cells. These anti-EGFR-scFvs are useful as therapeutic and/or diagnostic agents.
    Type: Application
    Filed: November 6, 2003
    Publication date: April 15, 2004
    Applicant: UAB Research Foundation
    Inventors: Kevin Paul Raisch, David T. Curiel, James Alan Bonner
  • Human anti-epidermal growth factor receptor single-chain antibodies
    Patent number: 6699473
    Abstract: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal growth factor receptor and the truncated and/or mutated epidermal growth factor receptor on human cells. These anti-EGFR-scFvs are useful as therapeutic and/or diagnostic agents.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: March 2, 2004
    Assignee: UAB Research Foundation
    Inventors: Kevin Paul Raisch, David T. Curiel, James Alan Bonner
  • Human anti-epidermal growth factor receptor single-chain antibodies
    Publication number: 20020058033
    Abstract: Human anti-epidermal growth factor receptor (EGFR) single-chain antibodies (scFvs) were isolated from a human IgM phage display library using purified epidermal growth factor receptor as antigen. Two isolates with different amino acid sequences were identified by ELISA as epidermal growth factor receptor-specific. The scFvs bind to the full length epidermal growth factor receptor and the truncated and/or mutated epidermal growth factor receptor on human cells. These anti-EGFR-scFvs are useful as therapeutic and/or diagnostic agents.
    Type: Application
    Filed: October 12, 2001
    Publication date: May 16, 2002
    Inventors: Kevin Paul Raisch, David T. Curiel, James Alan Bonner