Patents by Inventor Kevin R. Gutshall

Kevin R. Gutshall has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System and method for determining known DNA variants with temperature gradient electrophoresis
    Patent number: 7282126
    Abstract: The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first variant site. The first amplicons are combined with first and second different polynucleotide controls, the first and second polynucleotide controls differing by at least one base therealong, the position of the at least one differing base corresponding to the first variant site of the sample polynucleotide. A plurality of first duplexes are prepared, each of at least some of the first duplexes comprising (i) a polynucleotide strand of one of the first amplicons and (ii) a complementary polynucleotide strand of the first polynucleotide control.
    Type: Grant
    Filed: July 14, 2003
    Date of Patent: October 16, 2007
    Assignee: SpectruMedix LLC
    Inventors: Zhaowei Liu, Zhiyong Guo, Christina Maye, Kevin R. Gutshall
  • System and method for determining known DNA variants with temperature gradient electrophoresis
    Publication number: 20040076947
    Abstract: The present invention relates to a method of determining the genotype of a sample polynucleotide having at least a first variant site. At least a portion of the sample polynucleotide is amplified to obtain first amplicons, the first amplicons including the first variant site. The first amplicons are combined with first and second different polynucleotide controls, the first and second polynucleotide controls differing by at least one base therealong, the position of the at least one differing base corresponding to the first variant site of the sample polynucleotide. A plurality of first duplexes are prepared, each of at least some of the first duplexes comprising (i) a polynucleotide strand of one of the first amplicons and (ii) a complementary polynucleotide strand of the first polynucleotide control.
    Type: Application
    Filed: July 14, 2003
    Publication date: April 22, 2004
    Inventors: Zhaowei Liu, Zhiyong Guo, Christina Maye, Kevin R. Gutshall
  • Stain removing compositions containing particular isolated and pure proteolytic enzymes
    Patent number: 6326346
    Abstract: Stain removing compositions which can be granular detergents, liquid detergents, granular stain removers, liquid stain removers, household cleaners, food industrial cleaners, and the like, containing proteolytic enzymes derived from bacterium No. 177, are effective low temperature (0° C.-50° C.) stain removers.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: December 4, 2001
    Assignees: The Clorox Company, The Penn State Research Foundation
    Inventors: Jean E. Brenchley, Jennifer Loveland-Curtze, Kevin R. Gutshall, Vickie L. Humphrey