Patents by Inventor Kevin R. Roesch

Kevin R. Roesch has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
    Patent number: 9415044
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: August 16, 2016
    Assignee: Mallinckrodt LLC
    Inventors: Peter X. Wang, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar, Jr., Gary L. Cantrell
  • Process for the Preparation of Quaternary N-Alkyl Morphinan Alkaloid Salts
    Publication number: 20150164886
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Application
    Filed: September 3, 2009
    Publication date: June 18, 2015
    Applicant: Mallinckrodt Inc.
    Inventors: Peter X. Wang, Gary L. Cantrell, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar
  • Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
    Patent number: 9040726
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: May 26, 2015
    Assignee: Mallinckrodt LLC
    Inventors: Peter X. Wang, Gary L. Cantrell, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar
  • PROCESS FOR THE PREPARATION OF QUATERNARY N-ALKYL MORPHINAN ALKALOID SALTS
    Publication number: 20150099773
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Application
    Filed: December 12, 2014
    Publication date: April 9, 2015
    Inventors: Peter X. Wang, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar, Jr., Gary L. Cantrell
  • Process for the preparation of quaternary N-alkyl morphinan alkaloid salts
    Patent number: 8669366
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Grant
    Filed: March 6, 2008
    Date of Patent: March 11, 2014
    Assignee: Mallinckrodt LLC
    Inventors: Peter X. Wang, Gary L. Cantrell, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar, Jr.
  • Crystalline forms of naltrexone methobromide
    Patent number: 8383649
    Abstract: The present invention relates to novel crystalline forms of naltrexone methobromide including hydrated and solvated forms. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline forms of naltrexone methobromide, as well as methods of treating or preventing opioid induced side effects by administering the pharmaceutical compositions.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: February 26, 2013
    Assignee: Mallinckrodt LLC
    Inventors: Gary A. Nichols, Robert E. Halvachs, Gary L. Cantrell, Kevin R. Roesch, Joseph P. Haar, Jr.
  • Stepwise Process for the Production of Alkaloid Salts
    Publication number: 20130035488
    Abstract: The present invention provides to an improved process for preparing alkaloid salts. In particular, the process comprises a stepwise addition of an acid to an alkaloid chosen from hydrocodone, codeine, and dihydrocodeine to form a flowable mixture of the alkaloid salt.
    Type: Application
    Filed: August 1, 2012
    Publication date: February 7, 2013
    Applicant: Mallinckrodt LLC
    Inventors: Bradley R. Jones, Joseph P. Haar, JR., Kevin R. Roesch, Leslie L. Vanderkolk
  • Process for the Preparation of Quaternary N-Alkyl Morphinan Alkaloid Salts
    Publication number: 20110082297
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Application
    Filed: March 6, 2008
    Publication date: April 7, 2011
    Inventors: Peter X. Wang, Gary L. Cantrell, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar, JR.
  • Crystalline Forms of Naltrexone Methobromide
    Publication number: 20100324078
    Abstract: The present invention relates to novel crystalline forms of naltrexone methobromide including hydrated and solvated forms. The invention also describes methods of preparing the various crystalline forms. The present invention also relates to pharmaceutical compositions containing crystalline forms of naltrexone methobromide, as well as methods of treating or preventing opioid induced side effects by administering the pharmaceutical compositions.
    Type: Application
    Filed: June 25, 2008
    Publication date: December 23, 2010
    Inventors: Gary A. Nichols, Robert E. Halvachs, Gary L. Cantrell, Kevin R. Roesch, Joseph P. Haar, JR.
  • Preparation of 6-Keto, 3-Alkoxy Morphinans
    Publication number: 20100261906
    Abstract: The present invention provides processes for the preparation of saturated 6-keto, 3-alkoxy morphinans from unsaturated 6-hydroxy, 3-hydroxy morphinans, In particular, the invention provides processes that utilize catalytic isomerization and alkylation reactions for the preparation of saturated 6-keto, 3-alkoxy morphinans.
    Type: Application
    Filed: April 9, 2010
    Publication date: October 14, 2010
    Applicant: Mallinckrodt Inc.
    Inventors: Joseph P. Haar, JR., Kevin R. Roesch, David E. Gindelberger
  • Process for the Preparation of Quaternary N-Alkyl Morphinan Alkaloid Salts
    Publication number: 20100035910
    Abstract: An improved process for the N-alkylation of tertiary morphinan alkaloid bases to form the corresponding quaternary morphinan alkaloid derivatives.
    Type: Application
    Filed: September 3, 2009
    Publication date: February 11, 2010
    Applicant: Mallinckrodt Inc.
    Inventors: Peter X. Wang, Gary L. Cantrell, Robert E. Halvachs, Kevin R. Roesch, Henry J. Buehler, Joseph P. Haar