Abstract: A method for configuring a system having a wearable optical unit is disclosed. The method includes powering on the system, and in response to the system being powered on, using one or more processors to control the system to: determine whether to cause the system to run a configuration workflow, and in response to determining to cause the system to run the configuration workflow, (a) control the system in connection with configuring an interpupillary distance (IPD) for a user of the system, (b) determine whether the IPD is configured for the user, and (c) in response to determining that the IPD is configured for the user, control the system in connection with configuring a focus of the optical unit.

Abstract: Devices, systems and techniques are used for cancer treatment. An example control device may be configured to be communicatively coupled to a radiation source of a radiotherapy device and a position sensor of the radiotherapy device. The example control device may be used to calculate, for a sliding window of a radiotherapy treatment, a positional error between: a measured target position signal determined from a series of images and sampled at the acquisition times of the images, and an estimated target position signal. The example control device may generate a computer-executable instruction configured to alter the radiotherapy treatment in response to the positional error violating a threshold.

Abstract: The present disclosure provides heterocyclic amide and urea compounds and compositions thereof useful for inhibiting JAK2.

Abstract: A dispensing tip assembly includes a foodstuff additive dispenser for a pressurized foodstuff container. A tip body of the dispensing tip assembly may have low pressure zone in which fluid pressure is lower than fluid pressure upstream of the low pressure zone as flowable foodstuff from the foodstuff container flows through the internal flow passage toward an open downstream end of the tip body. The dispenser tip assembly may include one or more of duckbill valves tethered to one another, and/or a plurality of injection ports and/or structure for one-direction dispensing, and/or internal fins to couple to an actuator of the foodstuff container, and/or an anti-rotation device, and/or a collar for attaching a bulb or pod of the tip body, and/or an ergonomic and functional bulb.

Abstract: This invention relates to novel whitening agents for cellulosic substrates. The whitening agents are comprised of at least two components: at least one chromophore component and at least one polymeric component. Suitable chromophore components generally fluoresce blue, red, violet, or purple color when exposed to ultraviolet light, or they may absorb light to reflect these same shades. The whitening agents are further characterized by having a dispersion component value of the Hansen Solubility Parameter of less than or equal to about 17 MPa0.5. This invention also relates to laundry care compositions including but not limited to liquid and/or powder laundry detergent formulations and rinse added fabric softening (RAFS) compositions that comprise such whitening agents.

Abstract: The present application provides for IL-2 muteins, compositions comprising the same, and methods of using the same.

Abstract: A method for making an antimicrobial composite film can include forming a first coating layer by applying a first coating material on a substrate and forming a second coating layer by applying a second coating material on the first coating layer. The first coating material can comprise a first resin. The second coating material can comprise an antimicrobial material in a second resin or a dispersion. The first coating material can have a lower concentration of the antimicrobial material than the second coating material. The first and second coating layers can cooperatively define a composite film. The antimicrobial material can be asymmetrically dispersed in the composite film such that the antimicrobial material is concentrated closer to the outer surface of the composite film than to the inner surface of the composite film.

Abstract: Provided herein are pharmaceutically acceptable sodium thiosulfate and pharmaceutical compositions thereof. Also provided herein are methods for determining the total non-purgeable organic carbon in a sodium thiosulfate-containing sample. Further provided herein are methods for producing pharmaceutically acceptable sodium thiosulfate. Still further provided herein are methods of treatment comprising the administration of pharmaceutically acceptable sodium thiosulfate.

Abstract: Timing-based methods, systems, and computer readable mediums for a gated linear accelerator include synchronising a local clock of the linear accelerator with a clock of a patient monitoring system, determining latencies within one or more MR-gated radiotherapy processes and implementing latency based interlocks.

Abstract: The present invention relates to quinazolinones and related compounds which degrade PARP14 and are useful, for example, in the treatment of cancer and inflammatory diseases.

Abstract: Provided is a clutch assembly, a SSSV, and a method for operating an SSSV. The clutch assembly, in one aspect, includes an output coupler housing, an input shaft, and an electromagnet coupled to the input shaft. In at least one aspect, the electromagnet is configured to axially translate the output coupler housing from a de-coupled state to a coupled state when the electromagnet is energized. The clutch assembly, in one aspect, further includes one or more grooves located in one of an outer surface of the input shaft or an inner surface of the central opening, and one or more engagement members located in the other of the inner surface of the central opening or the outer surface of the input shaft.

Abstract: A patient containment system for securing a patient to a patient transport apparatus, comprising a first lower strap and a second lower strap. Each of the first lower strap and the second lower strap have a thigh region, a waist region, and a connection region arranged between the thigh region and the waist region. A first connector is coupled to the connection region of the first lower strap. A second connector is coupled to the connection region of the second lower strap, and is configured to releasably attach to the first connector to at least partially limit movement of the first lower strap relative to the second lower strap. The connection region defines a connection width, and the thigh region defines a thigh width larger than the connection width.

Abstract: An apparatus that forms bundles of glass articles includes a glass article infeed station including an infeed conveyor that continuously transports individual glass articles to a layer separating conveyor. The layer separating conveyor includes a conveyor belt that forms a layer of side-by-side glass articles. A robotic lift assembly is configured to place the layer of side-by-side glass articles together on a layer separation insert. The layer separation insert has side-by-side slots that each receive a single glass article of the layer of side-by-side glass articles.

Abstract: Ingestible devices can directly deliver therapeutic agents to desired tissue(s) of the GI tract of a subject, such as the submucosa, the mucosa, and/or the mucus layer of the GI tract, and methods of using the same. The ingestible devices can deliver therapeutic agents in a safe, effective, and reliable manner. The disclosure also provides pharmaceutical compositions for use in methods of treating a disease or condition in a subject in need thereof.

Abstract: A system and a method for performing a test of an application using an automation bot are provided. The method comprises accessing the application to be tested. The method comprises executing the test of the application using the automation bot. The automation bot is configured to interact with one or more other applications. The one or more other applications are different from the application. The method comprises determining one or more test results of the application based on the execution of the test. Further, the method comprises generating a notification indicative of the determined one or more test results.

Abstract: A surgical robotic system includes at least one eye tracking system positioned detect the direction of at least one user's gaze. Input derived from the eye tracking system may be used to enter commands to the surgical robotic system depending on the directions of the gaze detected or other aspects of the gaze such as pupil dilation or speed of eye movement.

Abstract: Methods, devices and systems are disclosed for inter-app communications between software applications on a mobile communications device. In one aspect, a computer-readable medium on a mobile computing device comprising an inter-application communication data structure to facilitate transitioning and distributing data between software applications in a shared app group for an operating system of the mobile computing device includes a scheme field of the data structure providing a scheme id associated with a target software app to transition to from a source software app, wherein the scheme id is listed on a scheme list stored with the source software app; and a payload field of the data structure providing data and/or an identification where to access data in a shared file system accessible to the software applications in the shared app group, wherein the payload field is encrypted.

Abstract: Methods and compositions for processing a gas produced from an oil and gas well are provided. In some embodiments, the compositions include a wellbore penetrating at least a portion of a subterranean formation. The compositions further include one or more fluid flow paths in fluid communication with the wellbore, the one or more fluid flow paths having at least a first segment and a second segment. The compositions further include at least one heat exchanger. The compositions further include an expander coupled to a generator in fluid communication with the gas in the second segment. The gas in the first segment flows through the at least one heat exchanger wherein it is cooled to the point of forming CNG, and the gas in the second segment flows through the expander to generate electricity.

Abstract: Various aspects of the subject technology relate to systems, methods, and machine-readable media for proposing blocks to be added to a blockchain. Various aspects may include performing adding block headers to a first blockchain, wherein the block headers reference a set of validators. Aspects may also include adding a temporal parameter to each block header. Aspects may also include determining, based on a block signature from a block header and from the set of validators, a proposer of candidate blocks for addition to the blockchain. Aspects may also include sampling, based on a temporal parameter, a subset of validators of the set of validators. Aspects may include increasing the proposer to a plurality of proposers from the subset of validators by an incremental quantity based on a comparison of the temporal parameter to a threshold.

Abstract: A steerable delivery system is provided for delivering a replacement heart valve to a native heart valve location. The steerable delivery system includes an outer sheath assembly having a capsule along a distal end portion for retaining the replacement heart valve in a compressed configuration. The capsule is constructed to provide both compression resistance and flexibility. The capsule may be formed with an outer polymer layer, a metal middle layer located on a radially inner surface of the outer polymer layer, and an inner liner located on a radially inner surface of the metal middle layer. A fluoroelastomer layer is provided for bonding the inner liner to the metal middle layer. The metal middle layer is preferably a metal hypotube.