Patents by Inventor Kevin S. Gorski
Kevin S. Gorski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9370565Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: GrantFiled: October 31, 2013Date of Patent: June 21, 2016Assignee: The Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20140099307Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: October 31, 2013Publication date: April 10, 2014Applicant: The Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20120065385Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefore and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: September 23, 2011Publication date: March 15, 2012Inventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20120065374Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: September 23, 2011Publication date: March 15, 2012Inventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Patent number: 8053414Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: GrantFiled: October 31, 2007Date of Patent: November 8, 2011Assignee: The Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Patent number: 8053558Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: GrantFiled: October 31, 2007Date of Patent: November 8, 2011Assignee: The Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20100028381Abstract: The present invention provides pharmaceutical compositions that include an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel. In another aspect, the present invention also provides a method of eliciting an antigen-specific immune response in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to generate an immune response in the subject against the antigen. In yet another aspect, the present invention also provides a method of treating a condition in a subject. Generally, the method includes administering to the subject a pharmaceutical composition comprising an IRM-PEG complex and an antigen, formulated together in a thermoresponsive gel, in an amount effective to ameliorate at least one symptom or clinical sign of the condition.Type: ApplicationFiled: June 18, 2007Publication date: February 4, 2010Applicant: 3M INNOVATIVE PROPERTIES COMPANYInventors: Kevin S. Gorski, Ronnie Ortiz, James D. Stoesz, Isidro Angelo E. Zarraga
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Patent number: 7560540Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: GrantFiled: February 24, 2006Date of Patent: July 14, 2009Assignee: The Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Patent number: 7485432Abstract: Methods of identifying a compound that selectively modulates at least one TLR-mediated cellular activity are disclosed. Generally, the methods include identifying a compound as a compound that selectively modulates at least one TLR-mediated cellular activity if the compound modulates one TLR-mediated cellular activity to a different extent than it modulates a second TLR-mediated cellular activity. Compounds so identified and pharmaceutical compositions including such compounds are also disclosed. Methods of selectively modulating immune cells and methods of treating certain conditions are also provided. Such methods include administering to cells or a subject a compound that selectively modulates a TLR-mediated cellular activity.Type: GrantFiled: February 27, 2004Date of Patent: February 3, 2009Assignee: 3M Innovative Properties CompanyInventors: Jason R. Fink, Keith B. Gorden, Kevin S. Gorski, Shalley K. Gupta, Xiaohong Qiu, John P. Vasilakos
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Publication number: 20080241175Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: October 31, 2007Publication date: October 2, 2008Inventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20080226662Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: October 31, 2007Publication date: September 18, 2008Inventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Patent number: 7030219Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: GrantFiled: February 28, 2001Date of Patent: April 18, 2006Assignee: Johns Hopkins UniversityInventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng
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Publication number: 20040171086Abstract: Methods of identifying a compound that selectively modulates at least one TLR-mediated cellular activity are disclosed. Generally, the methods include identifying a compound as a compound that selectively modulates at least one TLR-mediated cellular activity if the compound modulates one TLR-mediated cellular activity to a different extent than it modulates a second TLR-mediated cellular activity. Compounds so identified and pharmaceutical compositions including such compounds are also disclosed. Methods of selectively modulating immune cells and methods of treating certain conditions are also provided. Such methods include administering to cells or a subject a compound that selectively modulates a TLR-mediated cellular activity.Type: ApplicationFiled: February 27, 2004Publication date: September 2, 2004Applicant: 3M Innovative Properties CompanyInventors: Jason R. Fink, Keith B. Gorden, Kevin S. Gorski, Shalley K. Gupta, Xiaohong Qiu, John P. Vasilakos
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Publication number: 20020091246Abstract: A novel costimulatory protein molecule, B7-DC, which is a member of the B7 family, is described as is DNA coding therefor and expression vectors comprising this DNA. B7-DC protein, fragments, fusion polypeptides/proteins and other functional derivatives, and transformed cells expressing B7-DC are useful in vaccine compositions and methods. Compositions and methods are disclosed for inducing potent T cell mediated responses that can be harnessed for anti-tumor and anti-viral immunity.Type: ApplicationFiled: February 28, 2001Publication date: July 11, 2002Inventors: Drew M. Pardoll, Haruo Tsuchiya, Kevin S. Gorski, Su-Yi Tseng