Patents by Inventor Kevin Schaab

Kevin Schaab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ISOTOPICALLY LABELED BILE ACID DERIVATIVES
    Publication number: 20230057232
    Abstract: The present application relates to isotopically labeled compounds of Formula I and methods of preparation and use thereof
    Type: Application
    Filed: September 7, 2022
    Publication date: February 23, 2023
    Applicant: INTERCEPT PHARMACEUTICALS, INC.
    Inventors: Gabriel GALVIN, Kevin SCHAAB, Matthew YANIK
  • Isotopically labeled bile acid derivatives
    Patent number: 11472831
    Abstract: The present application relates to isotopically labeled compounds of Formula I and methods of preparation and use thereof.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: October 18, 2022
    Assignee: Intercept Pharmaceuticals, Inc.
    Inventors: Gabriel Galvin, Kevin Schaab, Mathew Yanik
  • Methods and intermediates for the preparation bile acid derivatives
    Patent number: 11072631
    Abstract: The present invention relates to methods and novel intermediates useful in the preparation of a compound of formula (A) or a pharmaceutically acceptable salt thereof, comprising converting the aldehyde of a compound of formula (B) with a reducing agent to prepare a compound of formula (C) and converting the compound of formula (C) with a sulfating reagent to prepare a compound of formula (A). An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and intermediates described relates to the synthesis of bile acid derivatives which activate both FXR and TGR5.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: July 27, 2021
    Assignee: Intercept Pharmaceuticals, Inc.
    Inventors: Kevin Schaab, Paul E. Whitley, Flavio Chavez Lopez, Kayla R. Iorga
  • METHODS AND INTERMEDIATES FOR THE PREPARATION BILE ACID DERIVATIVES
    Publication number: 20200239515
    Abstract: The present invention relates to methods and novel intermediates useful in the preparation of a compound or a pharmaceutically acceptable salt thereof. An objective of the present invention is to provide methods of preparing bile acid derivatives and novel intermediates. A use of the methods and intermediates described relates to the synthesis of bile acid derivatives which activate both FXR and TGR5.
    Type: Application
    Filed: September 23, 2016
    Publication date: July 30, 2020
    Inventors: Kevin Schaab, Paul E. Whitley, Flavio Chavez, Kayia R. lorga
  • ISOTOPICALLY LABELED BILE ACID DERIVATIVES
    Publication number: 20200165290
    Abstract: The present application relates to isotopically labeled compounds of Formula I and methods of preparation and use thereof.
    Type: Application
    Filed: July 23, 2018
    Publication date: May 28, 2020
    Inventors: Gabriel GALVIN, Kevin SCHAAB, Mathew YANIK
  • CRYSTALLINE FORMS OF A BILE ACID DERIVATIVE
    Publication number: 20200024299
    Abstract: A crystalline form of a bile acid compound and methods of preparation and use thereof are described.
    Type: Application
    Filed: September 29, 2017
    Publication date: January 23, 2020
    Inventors: Rachel Pineda Strazik, Kevin Schaab, Alex Eberlin, Rosa Maria Espinosa