Patents by Inventor Kevin Schutz

Kevin Schutz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CH1 DOMAIN VARIANTS ENGINEERED FOR PREFERENTIAL LIGHT CHAIN PAIRING AND MULTISPECIFIC ANTIBODIES COMPRISING THE SAME
    Publication number: 20230265134
    Abstract: CH1 domain variants engineered for preferential binding to either a kappa CL domain or a lambda CL domain, as well as polypeptides, e.g., antibody heavy chains or antibodies, comprising such engineered CH1 domain variants, and pharmaceutical compositions comprising such CH1 domain variants and/or such polypeptides, and methods for making and using such CH1 domain variants are provided. The CH1 domain variants minimize heavy chain-light chain mispairing and promote cognate heavy chain-light chain pairing, thereby improving the generation of multispecific, e.g., bispecific, antibodies. Also provided are methods of making CH1 domain variant libraries and methods of identifying one or more CH1 domain variants.
    Type: Application
    Filed: September 30, 2020
    Publication date: August 24, 2023
    Inventors: Arvind SIVASUBRAMANIAN, Kevin SCHUTZ, Michaela HELBLE, Eric KRAULAND, Paul WIDBOOM
  • Anti-CD112R Compositions and Methods
    Publication number: 20220162317
    Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.
    Type: Application
    Filed: November 19, 2021
    Publication date: May 26, 2022
    Inventors: Bianka PRINZ, Nadthakarn BOLAND, Kevin SCHUTZ, John BUKOWSKI, Jennifer SYMONDS, James MOHAN, Marisella Panduro SICHEVA
  • Anti-CD112R compositions and methods
    Patent number: 11279758
    Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: March 22, 2022
    Assignee: Surface Oncology, Inc.
    Inventors: Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva
  • Anti-CD112R compositions and methods
    Patent number: 11214619
    Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: January 4, 2022
    Assignee: SURFACE ONCOLOGY, INC.
    Inventors: Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva
  • RGMC-SELECTIVE INHIBITORS AND USE THEREOF
    Publication number: 20210380669
    Abstract: Selective inhibitors of repulsive guidance molecule C (RGMc), are described. Related methods, including methods for making, as well as therapeutic use of these inhibitors in the treatment of disorders, such as anemia, are also provided.
    Type: Application
    Filed: October 23, 2019
    Publication date: December 9, 2021
    Inventors: Samantha Nicholls, Adriana Donovan, Meghan McDonald, Abhishek Datta, Allan Capili, Kevin B. Dagbay, Lorena Lerner, Leonard Ira Zon, Kevin Schutz, John Bukowski, Justin W. Jackson
  • Anti-CD112R Compositions and Methods
    Publication number: 20210253699
    Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.
    Type: Application
    Filed: July 19, 2019
    Publication date: August 19, 2021
    Applicant: Surface Oncology, Inc.
    Inventors: Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva
  • Anti-CD112R Compositions and Methods
    Publication number: 20200040081
    Abstract: The invention provides anti-CD112R antibody compositions and their use in treating cancer.
    Type: Application
    Filed: July 19, 2019
    Publication date: February 6, 2020
    Applicants: Surface Oncology, Inc., Adimab, LLC
    Inventors: Bianka Prinz, Nadthakarn Boland, Kevin Schutz, John Bukowski, Jennifer Symonds, James Mohan, Marisella Panduro Sicheva