Patents by Inventor KEVIN SHIANNA

KEVIN SHIANNA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC MARKERS ASSOCIATED WITH INTERFERON-ALPHA RESPONSE
    Publication number: 20130251677
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: May 30, 2013
    Publication date: September 26, 2013
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Arthur Bertelsen, Jacques Fellay, Dongliang Ge, David B. Goldstein, John G. McHutchison, Ping Qiu, Kevin Shianna, Jason S. Simon, Alexander J. Thompson, Thomas Urban
  • Genetic markers associated with interferon-alpha response
    Patent number: 8535887
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers are useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Grant
    Filed: May 21, 2010
    Date of Patent: September 17, 2013
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Arthur Bertelsen, Jacques Fellay, Dongliang Ge, David B. Goldstein, John G. McHutchison, Ping Qiu, Kevin Shianna, Jason S. Simon, Alexander J. Thompson, Thomas Urban
  • MARKERS ASSOCIATED WITH RIBAVIRIN-INDUCED ANEMIA
    Publication number: 20120282224
    Abstract: The present invention provides genetic markers and biomarkers that are associated with anemia induced by ribavirin therapy. The genetic markers are located in the ITPA gene and elsewhere on human chromosome 20 and the biomarkers are low ITPA activity phenotypes. These markers of ribavirin-induced anemia are useful, inter alia, to identify patients who are least likely to develop anemia upon treatment with ribavirin pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with ribavirin, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: November 5, 2010
    Publication date: November 8, 2012
    Inventors: Janice K. Albrecht, Clifford A. Brass, Jacques Fellay, Dongliang Ge, David B. Goldstein, Curtis Gumbs, John G. McHutchinson, Ping Qiu, Kevin Shianna, Alexander J. Thompson, Thomas J. Urban
  • GENETIC MARKERS ASSOCIATED WITH INTERFERON-ALPHA RESPONSE
    Publication number: 20100297080
    Abstract: The present invention provides genetic markers on human chromosome 19 that are associated with a beneficial response to interferon alpha (IFN-?). These IFN-? response markers arc useful, inter alia, to identify patients who are most likely to benefit from treatment with IFN-? pharmaceutical compositions and drug products, in methods of treating patients having a disease susceptible to treatment with an IFN-?, and in methods for selecting the most appropriate therapy for such patients.
    Type: Application
    Filed: May 21, 2010
    Publication date: November 25, 2010
    Inventors: ARTHUR BERTELSEN, JACQUES FELLAY, DONGLANG GE, DAVID GOLDSTEIN, JOHN G. MCHUTCHISON, NICHOLAS J. MURGOLO, PING QIU, ROBERT ORVILLE RALSTON, II, KEVIN SHIANNA, JASON S. SIMON, ALEXANDER J. THOMPSON, THOMAS URBAN