Patents by Inventor Kevin Sprott

Kevin Sprott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE
    Publication number: 20140371285
    Abstract: Salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Dosage forms and kits comprising salinomycin analogs and pharmaceutically acceptable compositions containing salinomycin analogs. Methods of using salinomycin analogs, pharmaceutically acceptable compositions, dosage forms, and kits for the treatment of proliferative diseases, e.g.
    Type: Application
    Filed: January 7, 2013
    Publication date: December 18, 2014
    Inventors: Kevin Sprott, Michael Lewis, Hyeongwook Choi, Frank Fang, Mingde Shan, Tsvetelina I. Lazarova, Lin Li, M. Arshad Siddiqui, Robin Larouche-Gauthier, Alexandre Lemire
  • Indole compounds
    Patent number: 8884020
    Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: November 11, 2014
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: John Jeffrey Talley, Kevin Sprott, James Philip Pearson, G. Todd Milne, Wayne Schairer, Jane Yang, Charles Kim, Timothy Barden, Regina Lundrigan, Ara Mermerian, Mark G. Currie
  • CRTH2 modulators
    Patent number: 8674115
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: March 18, 2014
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Ara Mermerian, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini
  • CRTH2 MODULATORS
    Publication number: 20130259830
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: June 24, 2011
    Publication date: October 3, 2013
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Timothy Barden, Colleen Hudson, James Jia, Charles Kim, Regina Graul, Ara Mermerian, Joel Moore, Kevin Sprott, Yueh-tyng Chien
  • Cannabinoid Agonists
    Publication number: 20130178453
    Abstract: The present disclosure relates to compounds useful as agonists of the cannabinoid receptors. The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment of various disorders, either alone or in combination therapy. The compounds of the invention have Formula (I).
    Type: Application
    Filed: February 9, 2011
    Publication date: July 11, 2013
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Jason Rohde, Bo Peng, Takashi Nakai, Kevin Sprott, Ara Mermerían, Wayne C. Schairer, Galen John Carey
  • FAAH Inhibitors
    Publication number: 20130109721
    Abstract: The present disclosure relates to N-benzyl pyrrole compounds of formula (I) useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment or prevention of various disorders.
    Type: Application
    Filed: December 8, 2010
    Publication date: May 2, 2013
    Applicant: Ironwood Pharmaceuticals, Inc.
    Inventors: Kevin Sprott, John Jeffrey Talley, Jane Yang, Bo Peng
  • CB Receptor Agonists
    Publication number: 20130029970
    Abstract: The present disclosure relates to compounds of formula I useful as agonists of cannabinoid receptors. The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the compositions in the treatment of various disorders.
    Type: Application
    Filed: July 9, 2010
    Publication date: January 31, 2013
    Applicant: IRONWOOD PHARMACEUTICALS, INC
    Inventors: Kevin Sprott, Jason Rohde, Takashi Nakai, Bo Peng, John Jeffrey Talley
  • COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2
    Publication number: 20120214807
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Application
    Filed: October 26, 2011
    Publication date: August 23, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Shomir Ghosh, Prakash Raman, Kevin Sprott, Amy M. Elder, Sian Griffiths, Francois Soucy, Qing Ye
  • COMPOUNDS USEFUL AS ANTAGONISTS OF CCR2
    Publication number: 20120208818
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Application
    Filed: October 10, 2011
    Publication date: August 16, 2012
    Applicant: Millennium Pharmaceuticals, Inc.
    Inventors: Amy M. Elder, Shomir Ghosh, Sian Griffiths, Prakash Raman, Francois Soucy, Kevin Sprott, Qing Ye
  • Compounds useful as antagonists of CCR2
    Patent number: 8067457
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 29, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Shomir Ghosh, Prakash Raman, Kevin Sprott, Amy M. Elder, Sian Griffiths, Francois Soucy, Qing Ye
  • Compounds useful as antagonists of CCR2
    Patent number: 8067415
    Abstract: The present invention provides compounds of general formula (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: November 29, 2011
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Amy M. Elder, Shomir Ghosh, Sian Griffiths, Prakash Raman, Francois Soucy, Kevin Sprott, Qing Ye
  • CRTH2 MODULATORS
    Publication number: 20110150834
    Abstract: Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Inventors: Ara MERMERIAN, Bo Peng, Colleen Hudson, Charles Kim, Joel Moore, Jason Rohde, Kevin Sprott, Regina Graul, Takashi Nakai, James Jia, Wilmin Bartolini
  • Useful indole compounds
    Patent number: 7960544
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Grant
    Filed: December 18, 2006
    Date of Patent: June 14, 2011
    Assignee: Ironwood Pharmaceuticals, Inc.
    Inventors: Wilmin Bartolini, Brian M. Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • INDOLE COMPOUNDS
    Publication number: 20100197708
    Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.
    Type: Application
    Filed: August 7, 2007
    Publication date: August 5, 2010
    Inventors: John Jeffrey Talley, Kevin Sprott, James Philip Pearson, G. Todd Milne, Wayne Schairer, Jane Yang, Charles Kim, Timothy Barden, Regina Lundrigan, Ara Mermerian, Mark G. Currie
  • Compounds Useful as Antagonists of CCR2
    Publication number: 20100016289
    Abstract: The present invention provides compounds of general formula I: (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Application
    Filed: October 26, 2006
    Publication date: January 21, 2010
    Inventors: Kevin Sprott, Prakash Raman, Shomir Ghosh, Amy M. Elder, Sian Griffiths, Francois Soucy, Qing Ye
  • USEFUL INDOLE COMPOUNDS
    Publication number: 20090264653
    Abstract: Indoles that have activity as inhibitors of FAAH are described as are indoles and indole derivatives that have activity as inhibitors of DAO.
    Type: Application
    Filed: December 18, 2006
    Publication date: October 22, 2009
    Inventors: Wilmin Bartolini, Brian M Cali, Barbara Chen, Yueh-Tyng Chien, Mark G. Currie, G. Todd Milne, James Philip Pearson, John Jeffrey Talley, Jane Yang, Craig Zimmerman, Charles Kim, Kevin Sprott, Timothy Barden, Regina Lundigran, Ara Mermerian
  • Compounds Useful as Antagonists of CCR2
    Publication number: 20090197884
    Abstract: The present invention provides compounds of general formula I: or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Application
    Filed: October 26, 2006
    Publication date: August 6, 2009
    Applicant: MILLENNIUM PHARMACEUTICALS, INC.
    Inventors: Shomir Ghosh, Prakash Raman, Kevin Sprott, Amy M. Elder, Sian Griffiths, Francois Soucy, Qing Ye
  • Compounds Useful as Antagonists of CCR2
    Publication number: 20090163497
    Abstract: The present invention provides compounds of general formula (I) or a pharmaceutically acceptable salt thereof, wherein X, n, Y, and R1 are defined generally and in subsets herein. Compounds of the invention are inhibitors of CCR2 and accordingly are useful for the treatment of a variety of inflammatory, allergic, and autoimmune diseases, disorders, or conditions.
    Type: Application
    Filed: October 26, 2006
    Publication date: June 25, 2009
    Inventors: Amy M. Elder, Shomir Ghosh, Sian Griffiths, Prakash Raman, Francois Soucy, Kevin Sprott, Qing Ye
  • FAAH INHIBITORS
    Publication number: 20090118503
    Abstract: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.
    Type: Application
    Filed: June 20, 2008
    Publication date: May 7, 2009
    Inventors: Kevin Sprott, John Jeffrey Talley, James Philip Pearson, G. Todd Milne
  • PGD2 receptor antagonists for the treatment of inflammatory diseases
    Patent number: 7211672
    Abstract: Disclosed herein are compounds represented by Structural Formula (I): (I), wherein the variables are defined herein. Also disclosed is the use of such compounds for inhibiting the G-protein coupled receptor referred to as chemoattractant receptor-homologous molecule expressed on Th2 (“CRTH2”) for the treatment of inflammatory disorders.
    Type: Grant
    Filed: October 3, 2003
    Date of Patent: May 1, 2007
    Assignee: Millennium Pharmaceuticals, Inc.
    Inventors: Shomir Ghosh, Amy M. Elder, Kenneth G. Carson, Kevin Sprott, Sean Harrison