Patents by Inventor Kevin Stefanski

Kevin Stefanski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SOLID-STATE FORM OF CELECOXIB HAVING ENHANCED BIOAVAILABILITY
    Publication number: 20070202160
    Abstract: The selective cyclooxygenase-2 inhibitory drug celecoxib is provided in amorphous form. Also provided is a celecoxib drug substance wherein the celecoxib is present, in at least a detectable amount, as amorphous celecoxib. Also provided is a celecoxib-crystallization inhibitor composite comprising particles of amorphous celecoxib or a celecoxib drug substance of the invention in intimate association with one or more crystallization inhibitors, for example polymers. Also provided is a pharmaceutical composition comprising such a celecoxib-crystallization inhibitor composite and one or more excipients. Also provided are processes for preparing amorphous celecoxib, a celecoxib drug substance of the invention, a celecoxib-crystallization inhibitor composite of the invention, and a pharmaceutical composition of the invention.
    Type: Application
    Filed: May 4, 2007
    Publication date: August 30, 2007
    Inventors: Michael Hageman, Xiaorong He, Tugrul Kararli, Lesley Mackin, Patricia Miyake, Brian Rohrs, Kevin Stefanski
  • Solid-state form of celecoxib having enhanced bioavailability
    Publication number: 20050267190
    Abstract: The selective cyclooxygenase-2 inhibitory drug celecoxib is provided in amorphous form. Also provided is a celecoxib drug substance wherein the celecoxib is present, in at least a detectable amount, as amorphous celecoxib. Also provided is a celecoxib-crystallization inhibitor composite comprising particles of amorphous celecoxib or a celecoxib drug substance of the invention in intimate association with one or more crystallization inhibitors, for example polymers. Also provided is a pharmaceutical composition comprising such a celecoxib-crystallization inhibitor composite and one or more excipients. Also provided are processes for preparing amorphous celecoxib, a celecoxib drug substance of the invention, a celecoxib-crystallization inhibitor composite of the invention, and a pharmaceutical composition of the invention.
    Type: Application
    Filed: July 26, 2005
    Publication date: December 1, 2005
    Inventors: Michael Hageman, Xiaorong He, Tugrul Kararli, Lesley MacKin, Patricia Miyake, Brian Rohrs, Kevin Stefanski