Abstract: The disclosure relates to a particulate composition comprising ensifentrine, wherein the particulate composition further comprises: from greater than 0.00 wt % to 0.60 wt % of 1,3-bis(2-(2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea (BMIQU) relative to the total weight of ensifentrine; and from 0.00 wt % to 0.50 wt % of a biuret impurity of formula (A) relative to the total weight of ensifentrine. Further disclosed herein are liquid pharmaceutical compositions comprising the particulate composition, and a process for producing the particulate composition are also described.

Abstract: The disclosure relates to a particulate composition comprising ensifentrine, wherein the particulate composition further comprises: from greater than 0.00 wt % to 0.60 wt % of 1,3-bis(2-(2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea (BMIQU) relative to the total weight of ensifentrine; and from 0.00 wt % to 0.50 wt % of a biuret impurity of formula (A) relative to the total weight of ensifentrine. Further disclosed herein are liquid pharmaceutical compositions comprising the particulate composition, and a process for producing the particulate composition are also described.

Abstract: The disclosure relates to a particulate composition comprising ensifentrine, wherein the particulate composition further comprises: from greater than 0.00 wt % to 0.60 wt % of 1,3-bis(2-(2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea (BMIQU) relative to the total weight of ensifentrine; and from 0.00 wt % to 0.50 wt % of a biuret impurity of formula (A) relative to the total weight of ensifentrine. Further disclosed herein are liquid pharmaceutical compositions comprising the particulate composition, and a process for producing the particulate composition are also described.

Abstract: The disclosure relates to a particulate composition comprising ensifentrine, wherein the particulate composition further comprises: from greater than 0.00 wt % to 0.60 wt % of 1,3-bis(2-(2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido [6,1-a]isoquinolin-3(4H)-yl)ethyl)urea (BMIQU) relative to the total weight of ensifentrine; and from 0.00 wt % to 0.50 wt % of a biuret impurity of formula (A) relative to the total weight of ensifentrine. Further disclosed herein are liquid pharmaceutical compositions comprising the particulate composition, and a process for producing the particulate composition are also described.

Abstract: An electrification system is used to prevent the transmission of pathogens by dermal contact. The electrification system includes a skin-bracing object, a power supply, and at least one resistor. The skin-bracing object includes an object body and a conductive feature. The skin-bracing object is an object that regularly comes into physical contact with a user's skin. The object body is the structure of the skin-bracing object and can be, but is not limited to, a pillowcase, a bed sheet, a bed pad, a blanket, a piece of medical gauze, a face mask, a set of medical scrubs, or a food preparation surface. The power supply, the resistor, and the conductive feature are electrically connected in series to each other. Thus, the conductive feature carrier an electrical current to electrify pathogens that come into physical contact with the conductive feature.

Abstract: A method of communicating between nodes in a network where a node receives a sequence of symbols that will form a packet on a first communications channel and has a planned packet that it would send on a second communications channel. A destination is encoded into an arbitration portion of a header sequence of the packet, the header sequence comprising a sequence of symbols. The transmission on the second communications channel is as per the planned packet, for as long as the symbols of the planned packet match the symbols being received on the first channel. An arbitration decision is made when the symbols do not match, with the node either continuing to send the rest of the planned packet, or the rest of the packet being received on the first communications channel.

Abstract: Described herein are compounds, combinations of compounds, compositions, formulations, and methods of treating viruses, viral load, and manifestations of viral infections.

Abstract: A system (10) for converting power comprising a plurality of modules (14) connected in series and having each at least one DC power source. Storage devices (18) are provided with each module (14) to store power from the power source and voltage control circuitry (19) in each module (14) connects the storage device between a maximum module voltage, a minimum module voltage to create a stepwise approximation of a mains signal. A compensator unit (20) is provided in series with the modules (14) including a storage device charged by the power sources. While each of the modules (14) is supplying either its maximum or minimum voltage to the system a control unit ramps up or down the voltage between the input and output of the compensator unit (20) to follow the desired AC signal.

Abstract: A method of communicating between nodes in a network where a node receives a sequence of symbols that will form a packet on a first communications channel and has a planned packet that it would send on a second communications channel. A destination is encoded into an arbitration portion of a header sequence of the packet, the header sequence comprising a sequence of symbols. The transmission on the second communications channel is as per the planned packet, for as long as the symbols of the planned packet match the symbols being received on the first channel. An arbitration decision is made when the symbols do not match, with the node either continuing to send the rest of the planned packet, or the rest of the packet being received on the first communications channel.

Abstract: An electrification system is used to prevent the transmission of pathogens by dermal contact. The electrification system includes a skin-bracing object, a power supply, and at least one resistor. The skin-bracing object includes an object body and a conductive feature. The skin-bracing object is an object that regularly comes into physical contact with a user's skin. The object body is the structure of the skin-bracing object and can be, but is not limited to, a pillowcase, a bed sheet, a bed pad, a blanket, a piece of medical gauze, a face mask, a set of medical scrubs, or a food preparation surface. The power supply, the resistor, and the conductive feature are electrically connected in series to each other. Thus, the conductive feature carrier an electrical current to electrify pathogens that come into physical contact with the conductive feature.

Abstract: A method for detecting status information about a track pin of a track chain for heavy equipment includes disposing a track pin sensor within a void of the track pin; sensing with the track pin sensor a temperature characteristic of the track pin; determining status information based on the temperature characteristic; and wirelessly communicating the status information to a remote device. A method for detecting status information about a mechanical system that generates heat energy includes generating electrical energy based on the heat energy; providing the electrical energy to a control unit; sensing with the control unit a temperature characteristic of the mechanical system based on a voltage of the electrical energy; determining status information of the mechanical system based on the temperature characteristic; and wirelessly communicating the status information to a remote device.

Abstract: A battery pack (10) comprising a plurality of boards (12) having contacts thereon for contacting terminal of a plurality of cells (14). A plurality of cell guides (18) are provided to each receive a plurality of the cells (18). A plurality of tensioning members (32) are provided wherein the tensioning members (32) pass through holes (20) in the boards (12) to engage with first and second endmost boards (12) in order to pull together the boards (12) and thereby engage the terminal of the cells (14) with the contacts on the boards (12).

Abstract: An end cap for preventing ingress of moisture to the end face of a structural beam, wherein said structural beam comprises metal, stone, concrete, reinforced concrete, or a mixture thereof; said end cap comprising: (i) an end plate having a shape matching the transverse cross-section of said structural beam; and (ii) a skirt for holding said end plate in position; wherein said end plate and said skirt comprise or consist of a material for preventing transmission of moisture.

Abstract: A housing (10) comprising a main body including first and second side walls (16, 17) and first and second end walls (18, 19) extending between ends of the first and second side walls (16, 17). A plurality of mounting portions (26) are provided adjacent junction between the side walls (16, 17) and the end walls (18, 19). Bores (28) are provided in each of the mounting portions (26 and slots (36) are provided extending through outer surfaces of the mounting portions (26) into the bore (28). An elongate member of a frame (13) is receivable in the slots (28) of two or more of the mounting portions (26) such that fasteners (34) received in the bores (28) of said mounting portions (26) engage with the elongate member to secure the housing (12) to the frame (13).

Abstract: A track pin sensor for monitoring an operational status of a track pin of a track chain for heavy equipment. The track pin sensor may be incorporated into a communication system for monitoring a plurality of track pins of the track chain. A method of monitoring operational status of a track pin is also disclosed.

Abstract: A system and method for detecting connector (20) faults in a power conversion system (10). The system (10) comprises a plurality of series of modules (14) operable in a power conversion mode. A loop connection (30) is provided between the output of a final module (14) in the series and a first module (14) in the series and a loop switch (RL3) is provided in the loop connection (30). Loop current circuitry is provided in one or more of the modules (14) to generate a current flow within the loop and voltage measurement circuitry within each of the modules measures voltage of the input of the module relative to a local reference voltage and/or the output of the module relative to a local reference voltage. A control unit compares the voltages measured for the input and/or output of each of the modules against the voltages measured for the output and/or input of the adjacent modules to determine the resistance of the connection contacts between the module and the adjacent modules.

Abstract: Described is a method for converting power including controlling operation of a plurality of series connected modules including a DC power sources and storage devices such that the total voltage across the series connected modules includes an AC signal. A storage parameter is defined based on a sum of a function of the voltages in the storage devices in the modules and one or more voltage control levels are defined for each of or a plurality of the storage devices. An average current drawn from the series connected modules over a time period is set such that the storage parameter approaches a target value. The target value is decreased for a subsequent time period in the event that none the voltage control levels are reached and increased in the event that one or more of the voltage control levels are reached.

Abstract: A housing (10) comprising a main body including first and second side walls (16, 17) and first and second end walls (18, 19) extending between ends of the first and second side walls (16, 17). A plurality of mounting portions (26) are provided adjacent junction between the side walls (16, 17) and the end walls (18, 19). Bores (28) are provided in each of the mounting portions (26 and slots (36) are provided extending through outer surfaces of the mounting portions (26) into the bore (28). An elongate member of a frame (13) is receivable in the slots (28) of two or more of the mounting portions (26) such that fasteners (34) received in the bores (28) of said mounting portions (26) engage with the elongate member to secure the housing (12) to the frame (13).

Abstract: A comprehensive system, method, and apparatus of digitally researching, organizing, creating content and displaying biblical data according to the main versions of the Bible together and three axes (Text, Context, and Reception) encompassing most of the human sciences connected with the Bible, subdivided in many different Rubrics.

Abstract: A power conversion system comprising a plurality of modules each having an input and an output and being connected in series. Each module is connected to at least one DC power source that supplies power to the module. Voltage control circuitry provided within each of the modules to vary the voltage supplied between the input and the output between a maximum module voltage and a minimum module voltage. A control unit in communication with the voltage control circuitry of each of the modules varies the voltage supplied across the input and output of each of the modules such that the total voltage across the series connected modules forms an AC signal or a rectified version of an AC signal.