Patents by Inventor Kevin W. Plaxco

Kevin W. Plaxco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nucleotide-based probes and methods for the detection and quantification of macromolecules and other analytes
    Patent number: 9828628
    Abstract: Provided are unimolecular oligonucleotide probes for detecting a target in a sample. The probes use target binding-induced structural changes to detect the presence of the target in the sample. Also provided are methods of using the probes to detect a target in a sample.
    Type: Grant
    Filed: November 21, 2011
    Date of Patent: November 28, 2017
    Assignee: The Regents of the University of California
    Inventors: Alexis Vallé- Bélisle, Francesco Ricci, Ryan White, Andrew J. Bonham, Kevin W. Plaxco
  • Nucleotide-Based Probes and Methods for the Detection and Quantification of Macromolecules and Other Analytes
    Publication number: 20130288923
    Abstract: Provided are unimolecular oligonucleotide probes for detecting a target in a sample. The probes use target binding-induced structural changes to detect the presence of the target in the sample. Also provided are methods of using the probes to detect a target in a sample.
    Type: Application
    Filed: November 21, 2011
    Publication date: October 31, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Alexis Vallée-Bélisle, Francesco Ricci, Ryan White, Andrew J. Bonham, Kevin W. Plaxco
  • Biosensors utilizing ligand induced conformation changes
    Patent number: 6432723
    Abstract: A method for detecting the presence of a target analyte comprising binding a target analyte to a binding ligand comprising at least a first electron donor moiety and a second electron acceptor moiety; and detecting the electron transfer between the donor and acceptor, wherein there is a change in the amount of electron transfer between the donor and acceptor as a result of altering the structured state of the donor and acceptor caused by a conformational change in the binding ligand upon binding of the target ligand.
    Type: Grant
    Filed: January 21, 2000
    Date of Patent: August 13, 2002
    Assignee: Clinical Micro Sensors, Inc.
    Inventors: Kevin W. Plaxco, Jon Faiz Kayyem