Patents by Inventor Kevin William Leslie

Kevin William Leslie has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of 4-fluoro-2-methyl-1H-indol-5-ol
    Patent number: 8754240
    Abstract: The present invention relates to a chemical process for the manufacture of a compound of Formula II
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: June 17, 2014
    Assignee: AstraZeneca AB
    Inventors: Euan Alexander Arnott, John Crosby, Mathew Charles Evans, James Gair Ford, Martin Francis Jones, Kevin William Leslie, Ian Michael McFarlane, George Joseph Sependa
  • Process for Making a Metabotropic Glutamate Receptor Positive Allosteric Modulator - 874
    Publication number: 20130203995
    Abstract: Processes for making 7-methyl-5-(3piperazin-1-ylmethyl-[1,2,4]oxadiazol-5-yl)-2-(4-trifluoromethoxybenzyl)-2,3-dihydroisoindol-1-one
    Type: Application
    Filed: January 4, 2011
    Publication date: August 8, 2013
    Applicant: ASTRAZENECA AB
    Inventors: Alistair Boyd, Mark Richard Fielding, James Gair Ford, Lianne Frodsham, Michael D. Golden, Kevin William Leslie, Ben Mckeever-Abbas, Paula Tomlin
  • Chemical Process
    Publication number: 20110257395
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
    Type: Application
    Filed: November 17, 2010
    Publication date: October 20, 2011
    Applicant: AstraZeneca AB
    Inventors: Euan Alexander Arnott, John Crosby, Matthew Charles Evans, James Gair Ford, Martin Francis Jones, Kevin William Leslie, Ian Michael McFarlane, George Joseph Sependa
  • Chemical process
    Patent number: 7851623
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-[(4-fluoro-2-methy-1-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline starting from a compound of Formula IX: wherein R4 is a protecting group; or an intermediate there between, using process steps, reagents and conditions as described.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: December 14, 2010
    Assignee: AstraZeneca AB
    Inventors: Euan Alexander Arnott, John Crosby, Matthew Charles Evans, James Gair Ford, Martin Francis Jones, Kevin William Leslie, Ian Michael McFarlane, George Joseph Sependa
  • CHEMICAL PROCESS
    Publication number: 20080221322
    Abstract: The present invention relates to chemical processes for the manufacture of certain quinazoline derivatives, or pharmaceutically acceptable salts thereof. The invention also relates to processes for the manufacture of certain intermediates useful in the manufacture of the quinazoline derivatives and to processes for the manufacture of the quinazoline derivatives utilising said intermediates. In particular, the present invention relates to chemical processes and intermediates useful in the manufacture of the compound 4-(4-fluoro-2-methylindol-5-yloxy)-6-methoxy-7-(3-pyrrolidin-1-ylpropoxy)quinazoline.
    Type: Application
    Filed: October 31, 2007
    Publication date: September 11, 2008
    Applicant: AstraZeneca AB
    Inventors: Euan Alexander Arnott, John Crosby, Mathew Charles Evans, James Gair Ford, Martin Francis Jones, Kevin William Leslie, Ian Michael McFarlane, George Joseph Sependa
  • Chemical process
    Publication number: 20040101864
    Abstract: A process for the preparation of a salt of 5-phenylpentanoyl-(S)-arginyl-(S)-alanyl-{(S)-2-[(R)-3-amino-2-oxopyrrolidin-1-yl]propionyl}-(S)-alanyl-(S)-arginyl-(S)-alanyl-4-aminophenylacetamide (SEQ ID NO: 1) which comprises deprotection of a compound of the formula II or a salt thereof: wherein Pg and R1 are defined in the description. Also claimed are intermediates used in the process and the processes for the preparation of the intermediates.
    Type: Application
    Filed: June 24, 2003
    Publication date: May 27, 2004
    Applicant: AtraZeneca AB
    Inventors: Nigel Phillip Taylor, Kevin William Leslie, Phillip John Hogan, Francis Joseph Montgomery, Edward John Bush, Kay Alison Boardman, Claire Ingrid Pulling, Alan Charles Barker