Patents by Inventor Kevin X. Chen

Kevin X. Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties
    Patent number: 6846802
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Grant
    Filed: April 3, 2001
    Date of Patent: January 25, 2005
    Assignee: Schering Corporation
    Inventors: Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Tejal Parekh, Haining Gu, George F. Njoroge, Viyyoor Moopil Girijavallabhan, Ashit Ganguly, Anil Saksena, Edwin Jao, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison, Bancha Vibulbhan
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20040254117
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: July 19, 2001
    Publication date: December 16, 2004
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20030216325
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: July 19, 2001
    Publication date: November 20, 2003
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Raymond G. Lovey, Edwin Jao, Frank Bennett, Jinping L. McCormick, Haiyan Wang, Russell E. Pike, Stephane L. Bogen, Tin-Yau Chan, Yi-Tsung Liu, Zhaoning Zhu, F. George Njoroge, Ashok Arasappan, Tejal Parekh, Ashit K. Ganguly, Kevin X. Chen, Srikanth Venkatraman, Henry A. Vaccaro, Patrick A. Pinto, Bama Santhanam, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura, Wanli Wu, Siska Hendrata, Yuhua Huang
  • Novel compounds as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20030207861
    Abstract: The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: January 21, 2003
    Publication date: November 6, 2003
    Applicant: SCHERING CORPORATION
    Inventors: Ashok Arasappan, Frank Bennett, Stephane L. Bogen, Kevin X. Chen, Edwin Jao, Yi-Tsung Liu, Raymond G. Lovey, Vincent S. Madison, Latha G. Nair, F. George Njoroge, Anil K. Saksena, Mousumi Sannigrahi, Srikanth Venkatraman, Viyyoor M. Girijavallabhan
  • Novel peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20020160962
    Abstract: The present invention discloses novel peptide compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: July 19, 2001
    Publication date: October 31, 2002
    Inventors: Anil K. Saksena, Viyyoor Moopil Girijavallabhan, Stephane L. Bogen, Raymond G. Lovey, Edwin E. Jao, Frank Bennett, Jinping L. Mc Cormick, Haiyan Wang, Russell E. Pike, Yi-Tsung Liu, Tin-Yau Chan, Zhaoning Zhu, Ashok Arasappan, Kevin X. Chen, Srikanth Venkatraman, Tejal Parekh, Patrick A. Pinto, Bama Santhanam, F. George Njoroge, Ashit K. Ganguly, Henry A. Vaccaro, Scott Jeffrey Kemp, Odile Esther Levy, Marguerita Lim-Wilby, Susan Y. Tamura
  • Diaryl peptides as NS3-serine protease inhibitors of hepatitis C virus
    Publication number: 20020147139
    Abstract: The present invention is directed to certain diaryl amide compounds as NS3-Serine protease inhibitors of hepatitis C virus.
    Type: Application
    Filed: December 10, 2001
    Publication date: October 10, 2002
    Applicant: SCHERING CORPORATION
    Inventors: Zhaoning Zhu, Zhong-Yue Sun, Srikanth Venkatraman, F. George Njoroge, Ashok Arasappan, Bruce A. Malcolm, Viyyoor M. Girijavallabhan, Raymond G. Lovey, Kevin X. Chen
  • Macrocyclic NS3-serine protease inhibitors of hepatitis C virus comprising N-cyclic P2 moieties
    Publication number: 20020107181
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: April 3, 2001
    Publication date: August 8, 2002
    Inventors: Kevin X. Chen, Ashok Arasappan, Srikanth Venkatraman, Tejal Parekh, Haining Gu, F. George Njoroge, Viyyoor Moopil Girijavallabhan, Ashit Ganguly, Anil Saksena, Edwin Jao, Nanhua Hugh Yao, Andrew Joseph Prongay, Vincent Stewart Madison, Bancha Vibulbhan
  • Macrocyclic NS-3 serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties
    Publication number: 20020016294
    Abstract: The present invention discloses novel macrocyclic compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such macrocycles as well as methods of using them to treat disorders associated with the HCV protease.
    Type: Application
    Filed: April 17, 2001
    Publication date: February 7, 2002
    Inventors: Srikanth Venkatraman, Kevin X. Chen, Ashok Arasappan, F. George Njoroge, Viyyoor M. Girijavallabhan, Tin-Yau Chan, Brian A. Mc Kittrick, Andrew J. Prongay, Vincent S. Madison