Patents by Inventor Kevin Y. Lin

Kevin Y. Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Affinity-based detection of ligand-encoded synthetic biomarkers
    Patent number: 11977074
    Abstract: The invention relates to methods and products associated with in vivo enzyme profiling. In particular, biomarker nanoparticles capable of quantitatively detecting enzymatic activity in vivo are described. These nanoparticles can be used to detect in vivo enzyme activity. The invention also relates to products, kits, and databases for use in the methods of the invention.
    Type: Grant
    Filed: November 22, 2019
    Date of Patent: May 7, 2024
    Assignee: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, David K. Wood, Gabriel A. Kwong, Andrew David Warren, Kevin Y. Lin
  • AFFINITY-BASED DETECTION OF LIGAND-ENCODED SYNTHETIC BIOMARKERS
    Publication number: 20200225231
    Abstract: The invention relates to methods and products associated with in vivo enzyme profiling. In particular, biomarker nanoparticles capable of quantitatively detecting enzymatic activity in vivo are described. These nanoparticles can be used to detect in vivo enzyme activity. The invention also relates to products, kits, and databases for use in the methods of the invention.
    Type: Application
    Filed: November 22, 2019
    Publication date: July 16, 2020
    Applicant: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, David K. Wood, Gabriel A. Kwong, Andrew David Warren, Kevin Y. Lin
  • Affinity-based detection of ligand-encoded synthetic biomarkers
    Patent number: 10527619
    Abstract: The invention relates to methods and products associated with in vivo enzyme profiling. In particular, biomarker nanoparticles capable of quantitatively detecting enzymatic activity in vivo are described. These nanoparticles can be used to detect in vivo enzyme activity. The invention also relates to products, kits, and databases for use in the methods of the invention.
    Type: Grant
    Filed: June 6, 2014
    Date of Patent: January 7, 2020
    Assignee: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, David K. Wood, Gabriel A. Kwong, Andrew D. Warren, Kevin Y. Lin
  • Constrained cure component attach process for improved IC package warpage control
    Patent number: 10290569
    Abstract: An apparatus, comprising a first platform comprising a first working surface having a first non-planar portion; and a second platform comprising a second working surface having a second non-planar portion, wherein: the second working surface is opposite the first working surface, a distance between the first working surface and the second working surface is adjustable, the first non-planar portion comprises a first curved portion, and the second non-planar portion comprises a second curved portion opposite the first curved portion.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 14, 2019
    Assignee: Intel Corporation
    Inventors: Kyle Yazzie, Venkata Suresh R. Guthikonda, Patrick Nardi, Santosh Sankarasubramanian, Kevin Y. Lin, Leigh M. Tribolet, John L. Harper, Pramod Malatkar
  • CONSTRAINED CURE COMPONENT ATTACH PROCESS FOR IMPROVED IC PACKAGE WARPAGE CONTROL
    Publication number: 20190103345
    Abstract: An apparatus, comprising a first platform comprising a first working surface having a first non-planar portion; and a second platform comprising a second working surface having a second non-planar portion, wherein: the second working surface is opposite the first working surface, a distance between the first working surface and the second working surface is adjustable, the first non-planar portion comprises a first curved portion, and the second non-planar portion comprises a second curved portion opposite the first curved portion.
    Type: Application
    Filed: September 29, 2017
    Publication date: April 4, 2019
    Inventors: Kyle YAZZIE, Venkata Suresh R. GUTHIKONDA, Patrick NARDI, Santosh SANKARASUBRAMANIAN, Kevin Y. LIN, Leigh M. TRIBOLET, John L. HARPER, Pramod MALATKAR
  • AFFINITY-BASED DETECTION OF LIGAND-ENCODED SYNTHETIC BIOMARKERS
    Publication number: 20140363833
    Abstract: The invention relates to methods and products associated with in vivo enzyme profiling. In particular, biomarker nanoparticles capable of quantitatively detecting enzymatic activity in vivo are described. These nanoparticles can be used to detect in vivo enzyme activity. The invention also relates to products, kits, and databases for use in the methods of the invention.
    Type: Application
    Filed: June 6, 2014
    Publication date: December 11, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Sangeeta N. Bhatia, David K. Wood, Gabriel A. Kwong, Andrew D. Warren, Kevin Y. Lin
  • Polymers for delivery of nucleic acids
    Patent number: 6548302
    Abstract: The present invention relates to compositions and methods for delivery of nucleic acids. In particular, the invention provides a polymeric delivery formulation including a nucleic acid to be transfected into a host cell, formulated in a biodegradable polymer having phosphorous-based linkages.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: April 15, 2003
    Assignee: Johns Hopkins University School of Medicine
    Inventors: Hai-Quan Mao, Kevin Y. Lin, Bart S. Hendriks, Kam W. Leong, Michael F. Haller