Patents by Inventor Kexuan Tang

Kexuan Tang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230226018
    Abstract: An application of a compound using intra-cyclic peroxo-bridged sesquiterpenes as a parent nucleus in metabolism-related fatty liver diseases is provided. The compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus has the structure shown in Formula I, where A denotes O, —OH, OCH3, —OCH2CH3, or —OC4H5O3. The compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus is configured for preparing a drug or a composition for treating metabolism-related fatty liver diseases. The present invention demonstrates that the compound using intra-cyclic peroxo-bridged sesquiterpenes as the parent nucleus can improve the function of mitochondria. in liver cells and enhance the fatty acid ?-oxidation capacity thereof and can be used for the treatment of metabolic dysfunction due to mitochondrial dysfunction, as well as the resulting liver fat accumulation, inflammation, and fibrotic lesions.
    Type: Application
    Filed: February 7, 2021
    Publication date: July 20, 2023
    Applicants: SHANGHAI JIAO TONG UNIVERSITY, SUZHOU TANGJI BIOTECHNOLOGY CO., LTD.
    Inventors: Yuliang WANG, Kexuan TANG, Jiangao FAN, Jing ZENG, Xiaofen SUN
  • Patent number: 11208668
    Abstract: A gene RNAi vector is constructed with a V-ATPase subunit E gene fragment, a COO2 gene fragment, or a combination of the V-ATPase subunit E gene fragment and the COO2 gene fragment, then transferred into a plant, and expressed in the plant to produce dsRNA of the V-ATPase subunit E gene, the COO2 gene, or the combination of the V-ATPase subunit E gene and the COO2 double gene, and therefore the aphid growth is suppressed, and the plant is enhanced in pest resistance.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: December 28, 2021
    Assignee: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Kexuan Tang, Jingya Zhao, Xueqing Fu, Hang Liu, Qifang Pan, Tiantian Chen, Hongmei Qian, Xiaofen Sun
  • Publication number: 20210010018
    Abstract: The present invention discloses a nucleotide sequence and use thereof in increasing the density of secretory glandular trichomes in plants. The nucleotide sequence is selected from the group consisting of: 1) a nucleotide sequence according to any one of SEQ ID NOs: 1, 3 and 5; 2) a nucleotide sequence derived from the nucleotide sequence according to any one of SEQ ID NOs: 1, 3 and 5 through substitution, deletion or addition of one or more nucleotides; 3) a nucleotide sequence having at least 80% homology with any one of SEQ ID NOs: 1, 3 and 5. The present invention significantly increases the density of secretory glandular trichomes by transferring any one of the above nucleotide sequences into the plants by means of genetic engineering. Therefore, the invention shows great potential in insect resistance and production of specific metabolites, and has extremely high practical application value.
    Type: Application
    Filed: September 24, 2020
    Publication date: January 14, 2021
    Applicants: SHANGHAI JIAO TONG UNIVERSITY, Suzhou Tangen Biotechnology Co., Ltd
    Inventors: Kexuan TANG, Lihui XIE, Xueqing FU, Wei QIN, Ling LI, Hang LIU, Tiantian CHEN, Hongmei QIAN, Xiaofen SUN
  • Publication number: 20200283792
    Abstract: A gene RNAi vector is constructed with a V-ATPase subunit E gene fragment, a COO2 gene fragment, or a combination of the V-ATPase subunit E gene fragment and the COO2 gene fragment, then transferred into a plant, and expressed in the plant to produce dsRNA of the V-ATPase subunit E gene, the COO2 gene, or the combination of the V-ATPase subunit E gene and the COO2 double gene, and therefore the aphid growth is suppressed, and the plant is enhanced in pest resistance.
    Type: Application
    Filed: November 7, 2018
    Publication date: September 10, 2020
    Applicant: SHANGHAI JIAO TONG UNIVERSITY
    Inventors: Kexuan TANG, Jingya ZHAO, Xueqing FU, Hang LIU, Qifang PAN, Tiantian CHEN, Hongmei QIAN, Xiaofen SUN
  • Publication number: 20120041058
    Abstract: Composition of traditional Chinese medicine for reducing blood lipid with components of the crude drug of artemisinins and the crude drug of ursolic acid, wherein the ratio of the crude drug of artesunate and the crude drug of ursolic acid is 1:25-25:1 by weight. The preparation method of such composition includes the following steps: the crude drug of artesunate and the crude drug of ursolic acid are mixed at the weight ratio mentioned above, comminuted, then screened through 120 mesh sieve to obtain the composition; or the crude drug of artesunate and the crude drug of ursolic acid are weighed at the weight ratio mentioned above, comminuted, screened through 120 mesh sieve separately, then mixed and screened for three times to obtain the composition. The composition of the present invention can be formulated into formulations for injection, oral administration with pharmaceutically acceptable carriers, and can be used for preparing medicaments for reducing blood lipid.
    Type: Application
    Filed: March 9, 2010
    Publication date: February 16, 2012
    Applicant: ANJI GREEN LIFE BIOTECH CO., LTD.
    Inventors: Kexuan Tang, Yuliang Wang, Hailiang Xin, Luoou Tang
  • Patent number: 7893234
    Abstract: An isolated polypeptide comprising an amino acid sequence that is at least 62% identical to SEQ ID NO:2. The polypeptide, when present in a cell, increases the cell's ability to tolerate glyphosate. Also disclosed are related nucleic acid, antibody, vector, transgenic plant, as well as uses thereof.
    Type: Grant
    Filed: May 11, 2007
    Date of Patent: February 22, 2011
    Assignee: Si Chuan Heben Biotic Engineering Co. Ltd.
    Inventors: Min Lin, Kexuan Tang, Yiping Wang, Jin Wang, Yu Zhu
  • Publication number: 20090312185
    Abstract: An isolated polypeptide comprising an amino acid sequence that is at least 62% identical to SEQ ID NO:2. The polypeptide, when present in a cell, increases the cell's ability to tolerate glyphosate. Also disclosed are related nucleic acid, antibody, vector, transgenic plant, as well as uses thereof.
    Type: Application
    Filed: May 11, 2007
    Publication date: December 17, 2009
    Applicant: Si Chuan Heben Biotic Engineering Co. Ltd.
    Inventors: Min Lin, Kexuan Tang, Yiping Wang, Jin Wang, Yu Zhu
  • Patent number: 7238508
    Abstract: An isolated polypeptide comprising an amino acid sequence that is at least 62% identical to SEQ ID NO:2. The polypeptide, when present in a cell, increases the cell's ability to tolerate glyphosate. Also disclosed are related nucleic acid, antibody, vector, transgenic plant, as well as uses thereof.
    Type: Grant
    Filed: August 6, 2004
    Date of Patent: July 3, 2007
    Assignee: Si Chuan Heben Biotic Engineering Co. Ltd.
    Inventors: Min Lin, Kexuan Tang, Yiping Wang, Jin Wang, Yu Zhu
  • Publication number: 20050223436
    Abstract: An isolated polypeptide comprising an amino acid sequence that is at least 62% identical to SEQ ID NO:2. The polypeptide, when present in a cell, increases the cell's ability to tolerate glyphosate. Also disclosed are related nucleic acid, antibody, vector, transgenic plant, as well as uses thereof.
    Type: Application
    Filed: August 6, 2004
    Publication date: October 6, 2005
    Inventors: Min Lin, Kexuan Tang, Yiping Wang, Jin Wang, Yu Zhu