Patents by Inventor Keyu Liu

Keyu Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240310546
    Abstract: A real-time imaging system for a three-dimensional ultrasonic seismic model, which is used for three-dimensional real-time imaging of a seismic model in an indoor water tank experiment, comprising: an ultrasonic sensor network, comprising at least one emitting probe and at least one receiving probe spaced apart from each other to form a network, which is arranged above a seismic model; and a hardware subsystem, comprising a main control unit, an acquisition unit, an emitting unit, an industrial computer and a display, wherein the acquisition unit, the emitting unit and the industrial computer are electrically connected to the main control unit, the emitting probe is electrically connected to the emitting unit, the receiving probe is electrically connected to the acquisition unit, the display is electrically connected to the industrial computer, and a software subsystem is configured in the industrial computer.
    Type: Application
    Filed: May 22, 2024
    Publication date: September 19, 2024
    Inventors: Keyu LIU, Jianlei GAO, Jianliang LIU, Xueshen CAO, Xiao HE
  • Publication number: 20240046120
    Abstract: The present disclosure provides a training method and a prediction method for a diagenetic parameter prediction model based on an artificial intelligence algorithm, which includes: obtaining a plurality of diagenesis samples each including diagenetic condition parameters and an actual diagenetic parameter evolved therefrom; constructing an initial diagenetic parameter prediction model based on the diagenesis samples and a total dimension of the diagenetic condition parameters; and training the initial diagenetic parameter prediction model with the diagenesis samples so as to obtain a trained diagenetic parameter prediction model. The present disclosure can obtain a diagenetic parameter prediction model by training with the existing diagenesis samples, thereby solving problems of large amount of calculation, high uncertainty and large deviations in the prediction of the diagenetic parameters, which leads to a low evaluation accuracy of reservoirs and limits the oil and gas exploration.
    Type: Application
    Filed: July 20, 2023
    Publication date: February 8, 2024
    Applicant: China University of Petroleum-Beijing
    Inventors: Leilei YANG, Keyu LIU, Wei YANG, Hui WANG, Wenhao YANG, Zijie ZHOU, Ke XU, Yinglin CAO, Xiaowei LI, Yi LIU, Dawei WANG, Shu XU, Ziyang SONG
  • Publication number: 20230349864
    Abstract: A thermal simulation experiment method for hydrocarbon-water-rock interactions based on isotope tracing is disclosed. N-eicosane, water and feldspar grains are first heated and reacted in a high temperature high pressure (HTHP) reactor. The reactor is quenched in water to room temperature and samples from the reaction are tested to obtain the composition and content of gas products, the isotopic compositions of gas products, the water solutions and authigenic clays, the nuclear magnetic resonance (NMR) spectra of the liquid hydrocarbons and water solutions, and textures and compositions of minerals. The genetic mechanisms of mass exchange and occurrence of hydrocarbon-water-rock interactions are analyzed. A thermal simulation experiment method using multiple isotope tracing, calibrates the exchange processes and paths for H and O between the hydrocarbons, water and minerals to provide evidence for deciphering the mechanism of the organic-inorganic interactions is disclosed.
    Type: Application
    Filed: February 27, 2023
    Publication date: November 2, 2023
    Applicant: China University of Petroleum (East China)
    Inventors: Guanghui YUAN, Yingchang CAO, Zihao JIN, Keyu LIU
  • Patent number: 11487045
    Abstract: The present disclosure provides a method for recovering a porosity evolution process of sequence stratigraphy of carbonate rocks. The method comprises: a step of establishing a sequence stratigraphic framework of carbonate rocks; a step of dividing diagenetic stages; a step of simulating diagenesis and porosity evolution with increasing reservoir thickness and continuous superposition of multiple reservoirs during cyclic rise and fall of sea level to obtain a simulation result; and a step of calculating the porosity evolution in space over time by using the simulation result as initial values for simulation of diagenetic evolution process and simulating in stages and continuity the multi-stage diagenetic evolution process that the carbonate rock strata undergo after sediment based on the divided diagenetic stages.
    Type: Grant
    Filed: January 19, 2022
    Date of Patent: November 1, 2022
    Assignee: China University of Petroleum-Beijing
    Inventors: Leilei Yang, Donghua Chen, Guo Wei, Jing Hu, Weiquan Zhao, Keyu Liu, Jianliang Liu, Wei Yang, Xianglu Tang, Jin Lai
  • Publication number: 20220308257
    Abstract: The present disclosure provides a method for recovering a porosity evolution process of sequence stratigraphy of carbonate rocks. The method comprises: a step of establishing a sequence stratigraphic framework of carbonate rocks; a step of dividing diagenetic stages; a step of simulating diagenesis and porosity evolution with increasing reservoir thickness and continuous superposition of multiple reservoirs during cyclic rise and fall of sea level to obtain a simulation result; and a step of calculating the porosity evolution in space over time by using the simulation result as initial values for simulation of diagenetic evolution process and simulating in stages and continuity the multi-stage diagenetic evolution process that the carbonate rock strata undergo after sediment based on the divided diagenetic stages.
    Type: Application
    Filed: January 19, 2022
    Publication date: September 29, 2022
    Inventors: Leilei Yang, Donghua Chen, Guo Wei, Jing Hu, Weiquan Zhao, Keyu Liu, Jianliang Liu, Wei Yang, Xianglu Tang, Jin Lai
  • Publication number: 20220115725
    Abstract: The invention discloses a horizontal lead storage battery include a battery container and a cover; the interior of said battery container is installed with a partition that divides its inner cavity into a plurality of single cells, and each cell is installed with a plate group; the adjacent plate groups are connected by a bridge; said partition has a gap for the bridge to pass through, and a sealing component is installed at the gap; said sealing component comprises two sealing plates with a gap and sealed with said partition; said gap is filled with sealant. The gap of the partition of present invention is provided with two sealing plates, the gap between the two sealing plates is filled with sealant, and the tiny gap between the sealing plate and the partition is sealed by sealing, thereby improving the sealing effect.
    Type: Application
    Filed: December 20, 2021
    Publication date: April 14, 2022
    Inventors: Zhuo LIU, Guanrui YUAN, Qingshan TIAN, Xingyu CAO, Chao WANG, Keyu LIU, Jingyuan FAN, Wenwei ZHOU, Xufeng TANG, Qiushi YAO, Dan LI, Lu SHI
  • Patent number: 10884155
    Abstract: A method and an apparatus for measuring oil content of a tight reservoir based on nuclear magnetic resonance includes applying a pulse sequence to a tight reservoir rock, and after applying a first pulse and a last pulse in the pulse sequence, applying a gradient magnetic field to the tight reservoir rock, respectively, directions of the two applied gradient magnetic fields being opposite to each other, wherein the pulse sequence is composed of three 90° pulses; acquiring a nuclear magnetic resonance signal of the tight reservoir rock; and determining oil content of the tight reservoir rock according to an intensity of the nuclear magnetic resonance signal. The method can accurately distinguish an oil phase nuclear magnetic resonance signal and a water phase nuclear magnetic resonance signal in nanopores of tight reservoir rock, thereby effectively improving the accuracy of the detection result of the oil content of the tight reservoir rock.
    Type: Grant
    Filed: October 11, 2018
    Date of Patent: January 5, 2021
    Assignee: PetroChina Company Limited
    Inventors: Hua Tian, Shuichang Zhang, Shaobo Liu, Caineng Zou, Keyu Liu, Xuesong Lu, Mengjun Zhao, Lin Jiang, Xingzhi Ma, Bin Zhang, Junjia Fan, Peiqiang Yang
  • Patent number: 10598595
    Abstract: The invention provides a method for determining oil contents in rocks. The method comprises steps of: measuring a plurality of calibration oil samples having different oil contents, and acquiring a holographic fluorescence spectral intensity corresponding to the calibration oil samples; acquiring a fit relation between the holographic fluorescence spectral intensity and the oil contents of the calibration oil, according to the oil contents of the plurality of calibration oil samples and a plurality of three-dimensional fluorescence spectral intensities corresponding thereto; adding a certain amount of the calibration oil after dilution to rocks to be measured, acquiring a sample of the rocks to be measured and performing a holographic fluorescence measurement of the rock sample to be measured; and introducing the holographic fluorescence spectral intensity of the rock sample to be measured to the fit relation, thus an oil content of the rock sample to be measured is obtained.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: March 24, 2020
    Assignee: PETROCHINA COMPANY LIMITED
    Inventors: Hua Tian, Keyu Liu, Caineng Zou, Shuichang Zhang, Shaobo Liu, Xuesong Lu, Junjia Fan, Xiuli Li, Mengjun Zhao, Qingong Zhuo, Yanjie Gong
  • Patent number: 10533944
    Abstract: A device and method of determining thermal maturity of oil source rocks by total scanning fluorescence including testing the organic solution of the extract from a series of oil source rock samples collected at different depths by total scanning fluorescence; building a model for interpretation of the oil source rock maturity according to the variation with depth of the TSF Intensity parameter and the TSF R1 parameter obtained by total scanning fluorescence, and identifying the stage of initial oil generation, the stage of major oil generation and the stage of major gas generation; and establishing the relationship between the TSF Intensity parameter and/or the TSF R1 parameter with the existing characteristic parameters that quantitatively characterize the maturity of oil source rocks, thereby accomplishing the analysis and determination of the maturity of the oil source rocks.
    Type: Grant
    Filed: October 25, 2018
    Date of Patent: January 14, 2020
    Assignee: PETROCHINA COMPANY LIMITED
    Inventors: Keyu Liu, Hua Tian, Caineng Zou, Shuichang Zhang, Shaobo Liu, Mengjun Zhao, Xuesong Lu, Junjia Fan, Xiuli Li, Lili Gui, Qingong Zhuo, Xingzhi Ma, Yanjie Gong, Zhichao Yu, Qingyang Meng
  • Publication number: 20190170644
    Abstract: A device and method of determining thermal maturity of oil source rocks by total scanning fluorescence including testing the organic solution of the extract from a series of oil source rock samples collected at different depths by total scanning fluorescence; building a model for interpretation of the oil source rock maturity according to the variation with depth of the TSF Intensity parameter and the TSF R1 parameter obtained by total scanning fluorescence, and identifying the stage of initial oil generation, the stage of major oil generation and the stage of major gas generation; and establishing the relationship between the TSF Intensity parameter and/or the TSF R1 parameter with the existing characteristic parameters that quantitatively characterize the maturity of oil source rocks, thereby accomplishing the analysis and determination of the maturity of the oil source rocks.
    Type: Application
    Filed: October 25, 2018
    Publication date: June 6, 2019
    Applicant: PetroChina Company Limited
    Inventors: Keyu LIU, Hua TIAN, Caineng ZOU, Shuichang ZHANG, Shaobo LIU, Mengjun ZHAO, Xuesong LU, Junjia FAN, Xiuli LI, Lili GUI, Qingong ZHUO, Xingzhi MA, Yanjie GONG, Zhichao YU, Qingyang MENG
  • Publication number: 20190113649
    Abstract: A method and an apparatus for measuring oil content of a tight reservoir based on nuclear magnetic resonance includes applying a pulse sequence to a tight reservoir rock, and after applying a first pulse and a last pulse in the pulse sequence, applying a gradient magnetic field to the tight reservoir rock, respectively, directions of the two applied gradient magnetic fields being opposite to each other, wherein the pulse sequence is composed of three 90° pulses; acquiring a nuclear magnetic resonance signal of the tight reservoir rock; and determining oil content of the tight reservoir rock according to an intensity of the nuclear magnetic resonance signal. The method can accurately distinguish an oil phase nuclear magnetic resonance signal and a water phase nuclear magnetic resonance signal in nanopores of tight reservoir rock, thereby effectively improving the accuracy of the detection result of the oil content of the tight reservoir rock.
    Type: Application
    Filed: October 11, 2018
    Publication date: April 18, 2019
    Inventors: Hua TIAN, Shuichang ZHANG, Shaobo LIU, Caineng ZOU, Keyu LIU, Xuesong LU, Mengjun ZHAO, Lin JIANG, Xingzhi MA, Bin ZHANG, Junjia FAN, Peiqiang YANG
  • Publication number: 20180059022
    Abstract: The invention provides a method for determining oil contents in rocks. The method comprises steps of: measuring a plurality of calibration oil samples having different oil contents, and acquiring a holographic fluorescence spectral intensity corresponding to the calibration oil samples; acquiring a fit relation between the holographic fluorescence spectral intensity and the oil contents of the calibration oil, according to the oil contents of the plurality of calibration oil samples and a plurality of three-dimensional fluorescence spectral intensities corresponding thereto; adding a certain amount of the calibration oil after dilution to rocks to be measured, acquiring a sample of the rocks to be measured and performing a holographic fluorescence measurement of the rock sample to be measured; and introducing the holographic fluorescence spectral intensity of the rock sample to be measured to the fit relation, thus an oil content of the rock sample to be measured is obtained.
    Type: Application
    Filed: August 31, 2017
    Publication date: March 1, 2018
    Inventors: Hua Tian, Keyu Liu, Xuesong Lu, Junjia Fan, Xiuli Li, Mengjun Zhao, Qingong Zhuo, Yanjie Gong
  • Patent number: 9696321
    Abstract: The present invention provides a neutrophil activation regulator comprising a histidine-rich glycoprotein (HRG) for the treatment of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof. Further, the present invention provides methods for predicting the severity of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof, and methods for predicting the survival of a subject with systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation, that comprise determining the blood level of histidine-rich glycoprotein in the subject.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: July 4, 2017
    Assignee: National University Corporation Okayama University
    Inventors: Kosuke Kuroda, Hiroshi Morimatsu, Hidenori Wake, Shuji Mori, Masahiro Nishibori, Hideo Takahashi, Keyue Liu, Kiyoshi Teshigawara, Masakiyo Sakaguchi
  • Patent number: 9504731
    Abstract: The present invention provides a therapeutic agent, a treatment method and an inspection method for diseases caused by activation of neutrophils. More specifically, the invention relates to a neutrophil activation regulator which comprising a histidine-rich glycoprotein (HRG) as an active ingredient, and provides a therapeutic agent for diseases caused by neutrophil activation comprising the neutrophil activation regulator, a treatment method for diseases caused by neutrophil activation, and further an inspection method for diseases caused by neutrophil activation. The present invention is based on the neutrophil activation regulator including the HRG as an active ingredient. The present invention extends to the depressant agent for neutrophil-vascular endothelial cell interaction including the HRG of the present invention as an active ingredient, the treatment method for diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation.
    Type: Grant
    Filed: May 28, 2013
    Date of Patent: November 29, 2016
    Assignee: National University Corporation Okayama University
    Inventors: Masahiro Nishibori, Shuji Mori, Hidenori Wake, Hideo Takahashi, Keyue Liu, Kiyoshi Teshigawara, Masakiyo Sakaguchi
  • Publication number: 20160146835
    Abstract: The present invention provides a neutrophil activation regulator comprising a histidine-rich glycoprotein (HRG) for the treatment of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof. Further, the present invention provides methods for predicting the severity of systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation in a subject in need thereof, and methods for predicting the survival of a subject with systemic inflammatory response syndrome (SIRS), diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation, that comprise determining the blood level of histidine-rich glycoprotein in the subject.
    Type: Application
    Filed: January 14, 2016
    Publication date: May 26, 2016
    Applicant: National University Corporation Okayama University
    Inventors: Kosuke KURODA, Hiroshi MORIMATSU, Hidenori WAKE, Shuji MORI, Masahiro NISHIBORI, Hideo TAKAHASHI, Keyue LIU, Kiyoshi TESHIGAWARA, Masakiyo SAKAGUCHI
  • Publication number: 20150141322
    Abstract: The present invention provides a therapeutic agent, a treatment method and an inspection method for diseases caused by activation of neutrophils. More specifically, the invention relates to a neutrophil activation regulator which comprising a histidine-rich glycoprotein (HRG) as an active ingredient, and provides a therapeutic agent for diseases caused by neutrophil activation comprising the neutrophil activation regulator, a treatment method for diseases caused by neutrophil activation, and further an inspection method for diseases caused by neutrophil activation. The present invention is based on the neutrophil activation regulator including the HRG as an active ingredient. The present invention extends to the depressant agent for neutrophil-vascular endothelial cell interaction including the HRG of the present invention as an active ingredient, the treatment method for diseases caused by neutrophil activation and/or inflammatory diseases accompanied by neutrophil activation.
    Type: Application
    Filed: May 28, 2013
    Publication date: May 21, 2015
    Applicant: National University Corporation Okayama University
    Inventors: Masahiro Nishibori, Shuji Mori, Hidenori Wake, Hideo Takahashi, Keyue Liu, Kiyoshi Teshigawara, Masakiyo Sakaguchi
  • Publication number: 20120183556
    Abstract: The objective of the present invention is to provide an agent which is useful for suppressing actual atherosclerosis and has few side-effects. The suppressant for atherosclerosis according to the present invention is characterized in comprising an anti-HMGB1 monoclonal antibody binding to C-tail of HMGB1 as an active component.
    Type: Application
    Filed: September 27, 2010
    Publication date: July 19, 2012
    Inventors: Masahiro Nishibori, Hideo Takahashi, Shuji Mori, Keyue Liu, Yasuko Tomono
  • Publication number: 20100172909
    Abstract: The objective to be solved by the present invention is to provide a method for effectively suppressing cerebral edema. The method for suppressing cerebral edema according to the present invention is characterized in comprising a step of administering an anti-HMGB 1 antibody recognizing 208EEEDDDDE215 (SEQ ID NO:1) as an HMGB1 epitope.
    Type: Application
    Filed: January 4, 2010
    Publication date: July 8, 2010
    Inventors: Masahiro Nishibori, Shuji Mori, Hideo Takahashi, Yasuko Tomono, Naoto Adachi, Keyue Liu
  • Publication number: 20100113544
    Abstract: An object of the present invention is to provide a cerebral infarction suppressant which is effective for brain tissue necrosis after long-time ischemia as in actual cerebral infarction and has fewer side effects. The cerebral infarction suppressant of the present invention is characterized in that histidine is contained and the cerebral infarction is attributed to long-time ischemia.
    Type: Application
    Filed: September 1, 2005
    Publication date: May 6, 2010
    Applicant: Ehime University
    Inventors: Naoto Adachi, Keyue Liu, Tatsuru Arai
  • Publication number: 20090252739
    Abstract: An objective of the present invention is to provide a suppressant for cerebral infarction occurred after long-term ischemia associated with actual cerebral infarction, and has fewer side effects. The cerebral infarction suppressant of the present invention is characterized in comprising an anti-HMGB1 monoclonal antibody as an active ingredient.
    Type: Application
    Filed: October 13, 2006
    Publication date: October 8, 2009
    Inventors: Masahiro Nishibori, Shuji Mori, Hideo Takahashi, Yasuko Tomono, Naoto Adachi, Keyue Liu