Patents by Inventor Kezhong Zhang

Kezhong Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11816180
    Abstract: Disclosed is a method for classifying mixed signals, comprising: receiving mixed signals; performing calculation on a matrix corresponding to the mixed signals by means of a preset Principal Component Analysis method to obtain to-be-classified mixed signals and to determine the number of types of signals contained in the to-be-classified mixed signals; determining a separation matrix based on the number of types of signals contained in the to-be-classified mixed signals; separating individual signals in the to-be-classified mixed signals by means of the separation matrix to obtain to-be-identified signals; calculating a preset number of high-order cumulants corresponding to each to-be-identified signal in the to-be-identified signals respectively; taking the calculated high-order cumulants as characteristics of the to-be-identified signal corresponding to the high-order cumulants respectively; inputting the characteristics of the to-be-identified signal into a preset classification model; and obtaining a modu
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: November 14, 2023
    Assignee: BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS
    Inventors: Zhiyong Feng, Kezhong Zhang, Zhiqing Wei, Li Xu, Che Ji
  • Publication number: 20230102826
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Application
    Filed: December 2, 2022
    Publication date: March 30, 2023
    Applicant: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka
  • Patent number: 11524026
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Grant
    Filed: December 9, 2020
    Date of Patent: December 13, 2022
    Assignee: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka
  • Publication number: 20220180095
    Abstract: Disclosed is a method for classifying mixed signals, comprising: receiving mixed signals; performing calculation on a matrix corresponding to the mixed signals by means of a preset Principal Component Analysis method to obtain to-be-classified mixed signals and to determine the number of types of signals contained in the to-be-classified mixed signals; determining a separation matrix based on the number of types of signals contained in the to-be-classified mixed signals; separating individual signals in the to-be-classified mixed signals by means of the separation matrix to obtain to-be-identified signals; calculating a preset number of high-order cumulants corresponding to each to-be-identified signal in the to-be-identified signals respectively; taking the calculated high-order cumulants as characteristics of the to-be-identified signal corresponding to the high-order cumulants respectively; inputting the characteristics of the to-be-identified signal into a preset classification model; and obtaining a modu
    Type: Application
    Filed: March 10, 2020
    Publication date: June 9, 2022
    Inventors: Zhiyong Feng, Kezhong Zhang, Zhiqing Wei, Li Xu, Che Ji
  • Patent number: 11218354
    Abstract: Clustering-based methods, apparatuses for frequency offset determination and elimination and electronic devices are disclosed. The clustering-based method for frequency offset determination includes: determining a constellation diagram for a received signal; determining N different values within a preset frequency interval, as N frequency offset estimates for a frequency offset of the received signal; for each of the frequency offset estimates, correcting the constellation diagram based on the frequency offset estimate to obtain a corrected constellation diagram, clustering signal points on the corrected constellation diagram, and calculating an area of a signal region in the corrected constellation diagram after clustering; and determining a frequency offset estimate corresponding to a signal region with a minimum area as a value of the frequency offset. The embodiments of the present invention can improve the accuracy and stability of the calculated value of the frequency offset.
    Type: Grant
    Filed: August 16, 2019
    Date of Patent: January 4, 2022
    Assignee: Beijing University of Posts and Telecommunications
    Inventors: Zhiyong Feng, Kezhong Zhang, Che Ji, Zhiqing Wei
  • Publication number: 20210205350
    Abstract: Anti-heparanase compounds for the treatment of diabetes are described. The anti-heparanase compounds are high affinity, synthetic glycopolymers that result in minimal anticoagulant activity. Stereoselective fluorinated forms of these compounds are also provided.
    Type: Application
    Filed: December 9, 2020
    Publication date: July 8, 2021
    Applicant: Wayne State University
    Inventors: Hien M. Nguyen, Kezhong Zhang, Ravi Sankar Loka
  • Publication number: 20210203537
    Abstract: Clustering-based methods, apparatuses for frequency offset determination and elimination and electronic devices are disclosed. The clustering-based method for frequency offset determination includes: determining a constellation diagram for a received signal; determining N different values within a preset frequency interval, as N frequency offset estimates for a frequency offset of the received signal; for each of the frequency offset estimates, correcting the constellation diagram based on the frequency offset estimate to obtain a corrected constellation diagram, clustering signal points on the corrected constellation diagram, and calculating an area of a signal region in the corrected constellation diagram after clustering; and determining a frequency offset estimate corresponding to a signal region with a minimum area as a value of the frequency offset. The embodiments of the present invention can improve the accuracy and stability of the calculated value of the frequency offset.
    Type: Application
    Filed: August 16, 2019
    Publication date: July 1, 2021
    Inventors: Zhiyong FENG, Kezhong ZHANG, Che JI, Zhiqing WEI
  • Patent number: 10857210
    Abstract: Compositions and methods to promote wound healing are described. The compositions and methods up-regulate X-box binding protein 1 (XBP1) and/or inositol-requiring enzyme-1 (IRE-1). In various embodiments, the compositions and methods can be used to promote wound healing in diabetic subjects.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: December 8, 2020
    Assignee: Wayne State University
    Inventors: Kezhong Zhang, Jiemei Wang
  • Publication number: 20170007678
    Abstract: Compositions and methods to promote wound healing are described. The compositions and methods up-regulate X-box binding protein 1 (XBP1) and/or inositol-requiring enzyme-1 (IRE-1). In various embodiments, the compositions and methods can be used to promote wound healing in diabetic subjects.
    Type: Application
    Filed: July 6, 2016
    Publication date: January 12, 2017
    Applicant: WAYNE STATE UNIVERSITY
    Inventors: Kezhong Zhang, Jiemei Wang
  • Publication number: 20070111258
    Abstract: Methods and compositions are provided for modulating the acute phase response. In particular, methods and compositions are provided that inhibit the acute phase response, including expression or production of C-reactive protein (CRP). The invention accordingly has applicability to the modulation of innate immune responses and to cardiovascular diseases and disorders, particularly atherosclerosis. The instant methods and compositions are based on the discovery that the mammalian transcription factor CREBH is necessary for the induction of an acute phase response and/or an innate immune response.
    Type: Application
    Filed: June 20, 2006
    Publication date: May 17, 2007
    Inventors: Randal Kaufman, Kezhong Zhang