Patents by Inventor Kfir Molakandov

Kfir Molakandov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DIFFERENTIATING AND PURIFYING PANCREATIC ENDOCRINE CELLS
    Publication number: 20230248779
    Abstract: The present invention relates to compositions and methods comprising cell surface markers for pluripotent-derived cells, in particular, pancreatic endoderm-type cells, derived from pluripotent stem cells.
    Type: Application
    Filed: April 21, 2023
    Publication date: August 10, 2023
    Applicants: Kadimastem Ltd., Yeda Research and Development Co. Ltd.
    Inventors: Kfir MOLAKANDOV, Neta LAVON, Avital BECK, Michel REVEL, Ofer ELHANANI, Yoav SOEN, Michael WALKER, Arye HASSON
  • Methods for differentiating and purifying pancreatic endocrine cells
    Patent number: 11679133
    Abstract: The present invention relates to compositions and methods comprising cell surface markers for pluripotent-derived cells, in particular, pancreatic endoderm-type cells, derived from pluripotent stem cells.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: June 20, 2023
    Assignees: Kadimastem Ltd., Yeda Research and Development Co. Ltd.
    Inventors: Kfir Molakandov, Neta Lavon, Avital Beck, Michel Revel, Ofer Elhanani, Yoav Soen, Michael Walker, Arik Hasson
  • METHODS OF TREATING ACUTE RESPIRATORY DISTRESS SYNDROME
    Publication number: 20220387514
    Abstract: A method of treating acute respiratory distress syndrome (ARDS) in a subject in need thereof is provided. The method comprising administering to the subject a composition comprising a therapeutically effective amount of astrocytes, thereby treating the ARDS.
    Type: Application
    Filed: June 2, 2022
    Publication date: December 8, 2022
    Applicant: Kadimastem Ltd.
    Inventors: Michel REVEL, Michal IZRAEL, Julia Miriam WEISS, Kfir MOLAKANDOV
  • DIRECTED DIFFERENTIATION OF ASTROCYTES FROM HUMAN PLURIPOTENT STEM CELLS FOR USE IN DRUG SCREENING AND THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
    Publication number: 20210054334
    Abstract: The present invention discloses a method of identifying agents that affect human astrocytes functionality using ex-vivo differentiated pluripotent stem cells (PSC). In addition, the use of human progenitor astrocytes or human astrocytes for the treatment of Amyotrophic Lateral Sclerosis (ALS) in a human subject is also disclosed.
    Type: Application
    Filed: September 9, 2019
    Publication date: February 25, 2021
    Applicant: Kadimastem Ltd.
    Inventors: Michal Izrael, Michel Revel, Arik Hasson, Kfir Molakandov, Judith Chebath
  • Methods for Differentiating and Purifying Pancreatic Endocrine Cells
    Publication number: 20180369290
    Abstract: The present invention relates to compositions and methods comprising cell surface markers for pluripotent-derived cells, in particular, pancreatic endoderm-type cells, derived from pluripotent stem cells.
    Type: Application
    Filed: November 28, 2016
    Publication date: December 27, 2018
    Inventors: Kfir MOLAKANDOV, Neta LAVON, Avital BECK, Michel REVEL, Ofer ELHANANI, Yoav SOEN, Michael WALKER, Arik HASSON
  • DIRECTED DIFFERENTIATION OF ASTROCYTES FROM HUMAN PLURIPOTENT STEM CELLS FOR USE IN DRUG SCREENING AND THE TREATMENT OF AMYOTROPHIC LATERIAL SCLEROSIS (ALS)
    Publication number: 20180230427
    Abstract: The present invention discloses a method of identifying agents that affect human astrocytes functionality using ex-vivo differentiated pluripotent stem cells (PSC). In addition, the use of human progenitor astrocytes or human astrocytes for the treatment of Amyotrophic Lateral Sclerosis (ALS) in a human subject is also disclosed.
    Type: Application
    Filed: January 5, 2018
    Publication date: August 16, 2018
    Applicant: Kadimastem Ltd.
    Inventors: Michal Izrael, Michel Revel, Arik Hasson, Kfir Molakandov, Judith Chebath
  • DIRECTED DIFFERENTIATION OF ASTROCYTES FROM HUMAN PLURIPOTENT STEM CELLS FOR USE IN DRUG SCREENING AND THE TREATMENT OF AMYOTROPHIC LATERIAL SCLEROSIS (ALS)
    Publication number: 20160237404
    Abstract: The present invention discloses a method of identifying agents that affect human astrocytes functionality using ex-vivo differentiated pluripotent stem cells (PSC). In addition, the use of human progenitor astrocytes or human astrocytes for the treatment of Amyotrophic Lateral Sclerosis (ALS) in a human subject is also disclosed.
    Type: Application
    Filed: September 23, 2014
    Publication date: August 18, 2016
    Inventors: Michal IZRAEL, Michel REVEL, Arik HASSON, Kfir MOLAKANDOV, Judith CHEBATH
  • Insulin producing cells derived from pluripotent stem cells
    Patent number: 9404087
    Abstract: A method of generating islet cells from pluripotent stem cells is disclosed. The method comprises: (a) culturing the pluripotent stem cells in a differentiation medium so as to differentiate the pluripotent stem cells into endoderm cells; and (b) culturing the endoderm cells in a medium comprising at least one growth factor, a cAMP inducer and retinoic acid (RA), said at least one growth factor being selected from the group consisting of FGF10, bFGF and FGF7 so as to generate further differentiated cells; and (c) culturing the further differentiated cells in a medium comprising a maturation factor selected from the group consisting of nicotinamide, GLP-1 and exendin 4, thereby generating islet cells from pluripotent stem cells. Further methods of generating islet cells are also disclosed, isolated cell populations comprising same and uses thereof.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: August 2, 2016
    Assignee: Kadimastem Ltd.
    Inventors: Michel Revel, Judith Chebath, Guy Slutsky, Alon Levy, Michal Izrael, Arik Hasson, Kfir Molakandov, Rosalia Kaufman