Patents by Inventor Khairuzzaman Bashar Mullah

Khairuzzaman Bashar Mullah has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DIBENZOXANTHENE QUENCHERS, USES, AND METHODS OF PREPARATION
    Publication number: 20240110063
    Abstract: The present disclosure relates to dibenzoxanthene compounds that are efficient quenchers of fluorescence, for example in the far red and near infrared spectrum. Applications using the dibenzoxanthene quenching compounds and methods of making same are also described.
    Type: Application
    Filed: June 30, 2023
    Publication date: April 4, 2024
    Inventors: Andrew LEVITZ, Khairuzzaman Bashar MULLAH, Brian EVANS, Scott C. BENSON, Chris VONNEGUT
  • NOVEL QUENCHER AND REPORTER DYE COMBINATIONS
    Publication number: 20230124451
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Application
    Filed: December 7, 2022
    Publication date: April 20, 2023
    Inventors: Khairuzzaman Bashar MULLAH, Brian EVANS, Scott C. BENSON, Chu-An CHANG, Xiongwei YAN
  • Quencher and reporter dye combinations
    Patent number: 11535885
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: December 27, 2022
    Inventors: Khairuzzaman Bashar Mullah, Brian Evans, Scott C. Benson, Chu-An Chang, Xiongwei Yan
  • NOVEL QUENCHER AND REPORTER DYE COMBINATIONS
    Publication number: 20200407780
    Abstract: Disclosed is a probe for use in biological assays. The probe includes a fluorescent dye bound to a quencher compound through an oligonucleotide linker. Also disclosed are methods of using the probe, such as for a polymerase chain reaction (PCR), such as in a quantitative PCR reaction (qPCR), as well as kits including the probe.
    Type: Application
    Filed: March 1, 2019
    Publication date: December 31, 2020
    Inventors: Khairuzzaman Bashar MULLAH, Brian EVANS, Scott C. BENSON, Chu-An CHANG, Xiongwei YAN
  • Methods of detecting target nucleic acids
    Patent number: 10196680
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Grant
    Filed: June 5, 2017
    Date of Patent: February 5, 2019
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Muhammad A. Sharaf, Timothy Woudenberg, Khairuzzaman Bashar Mullah
  • SYNTHESIS OF 2', 3'-DIDEOXYNUCLEOSIDES FOR AUTOMATED DNA SYNTHESIS AND PYROPHOSPHOROLYSIS ACTIVATED POLYMERIZATION
    Publication number: 20170305954
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: July 6, 2017
    Publication date: October 26, 2017
    Applicant: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason
  • METHODS OF DETECTING TARGET NUCLEIC ACIDS
    Publication number: 20170275678
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Application
    Filed: June 5, 2017
    Publication date: September 28, 2017
    Inventors: Muhammad A. Sharaf, Timothy Woudenberg, Khairuzzaman Bashar Mullah
  • Synthesis of 2?,3?-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization
    Patent number: 9732112
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: August 15, 2017
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason
  • Methods of detecting target nucleic acids
    Patent number: 9677126
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: June 13, 2017
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Muhammad A. Sharaf, Timothy Woudenberg, Khairuzzaman Bashar Mullah
  • Use of antibody-surrogate antigen systems for detection of analytes
    Patent number: 9575069
    Abstract: Compositions, methods and kits for labeling proteins and uses in reporter systems for detecting, quantifying and/or characterizing analytes.
    Type: Grant
    Filed: November 8, 2013
    Date of Patent: February 21, 2017
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventors: Steven Menchen, Joe Y. Lam, Zhaochun Ma, Khairuzzaman Bashar Mullah
  • Methods of Detecting Target Nucleic Acids
    Publication number: 20160355877
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Application
    Filed: August 19, 2016
    Publication date: December 8, 2016
    Inventors: Muhammad A. SHARAF, Timothy WOUDENBERG, Khairuzzaman Bashar MULLAH
  • Methods of detecting target nucleic acids
    Patent number: 9434982
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Grant
    Filed: July 2, 2015
    Date of Patent: September 6, 2016
    Assignee: Applied Biosystems LLC
    Inventors: Muhammad A. Sharaf, Timothy Woudenberg, Khairuzzaman Bashar Mullah
  • Synthesis Of 2',3'-Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization
    Publication number: 20160108079
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: November 25, 2015
    Publication date: April 21, 2016
    Inventors: Zhaochun MA, Khairuzzaman Bashar MULLAH, Robert G. EASON
  • Synthesis of 2?, 3?-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization
    Patent number: 9228227
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: February 5, 2014
    Date of Patent: January 5, 2016
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert Eason
  • Methods of Detecting Target Nucleic Acids
    Publication number: 20150307925
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Application
    Filed: July 2, 2015
    Publication date: October 29, 2015
    Inventors: Muhammad A. SHARAF, Timothy WOUDENBERG, Khairuzzaman Bashar MULLAH
  • USE OF ANTIBODY-SURROGATE ANTIGEN SYSTEMS FOR DETECTION OF ANALYTES
    Publication number: 20150198605
    Abstract: Compositions, methods and kits for labeling proteins and uses in reporter systems for detecting, quantifying and/or characterizing analytes.
    Type: Application
    Filed: November 8, 2013
    Publication date: July 16, 2015
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventors: Steven MENCHEN, Joe Y. Lam, Zhaochun Ma, Khairuzzaman Bashar Mullah
  • Methods of detecting target nucleic acids
    Patent number: 9074252
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: July 7, 2015
    Assignee: Applied Biosystems, LLC
    Inventors: Muhammad A. Sharaf, Timothy Woudenberg, Khairuzzaman Bashar Mullah
  • Synthesis Of 2' , 3' -Dideoxynucleosides For Automated DNA Synthesis And Pyrophosphorolysis Activated Polymerization
    Publication number: 20150045547
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Application
    Filed: February 5, 2014
    Publication date: February 12, 2015
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Zhaochun MA, Khairuzzaman Bashar Mullah, Robert Eason
  • Methods of Detecting Target Nucleic Acids
    Publication number: 20140170656
    Abstract: The present disclosure relates to methods of identifying target nucleic acids by using coded molecules and its analysis by translocation through a nanopore. Generally, coded molecules are subject to a target polynucleotide dependent modification. The modified coded molecule is detected by isolating the modified coded molecules from the unmodified coded molecules prior to analysis through the nanopore or by detecting a change in the signal pattern of the coded molecule when analyzed through the nanopore.
    Type: Application
    Filed: December 20, 2013
    Publication date: June 19, 2014
    Applicant: LIFE TECHNOLOGIES CORPORATION
    Inventors: Muhammad A. SHARAF, Timothy WOUDENBERG, Khairuzzaman Bashar MULLAH
  • Synthesis of 2?,3?-dideoxynucleosides for automated DNA synthesis and pyrophosphorolysis activated polymerization
    Patent number: 8658776
    Abstract: Methods for preparation of 2?,3?-dideoxynucleotides support structures, such as 2?,3?-dideoxyguanosine, 2?,3?-dideoxyadenosine, and 3?-deoxythymidine support structures are disclosed. Various methods of using such structures are also provided, such as their use for automated DNA synthesis and pyrophosphorolysis activated polymerization.
    Type: Grant
    Filed: May 26, 2011
    Date of Patent: February 25, 2014
    Assignee: Life Technologies Corporation
    Inventors: Zhaochun Ma, Khairuzzaman Bashar Mullah, Robert G. Eason