Abstract: A mask with filter port is configured to cover a wearer's nose and mouth to protect the wearer from airborne microbes in the environment and/or minimize a risk of spreading airborne microbes from the user. The mask with filter port includes a substantially arcuate body wall, a slanted base at a lower end of the wall, an elastomeric seal extending from a face edge of the wall, a filter holder secured to the slanted base, and a pair of securing straps connected to the body wall. The elastomeric seal provides an interface between the body wall and the user's face. The securing straps secure the mask against the user's face, with the elastomeric seal pressing against the user's face.