Abstract: A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual's age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.

Abstract: Ophthalmic devices, such as contact lenses, may incorporate myopia control optics in combination with therapeutic agents also known to control myopia to create a drug delivery mechanism to inhibit or arrest the progression of myopia in individuals. Any number of contact lenses incorporating myopia control optics may be combined with a therapeutic agent such as atropine, atropine sulphate monohydrate, and/or pirenzepine.

Abstract: Ophthalmic lenses incorporate multifocal properties for the purpose of slowing, retarding, controlling or preventing myopia development or progression, correcting presbyopic vision or allowing extended depth of focus. The lens has electronically controlled adjustable focus where the change in focus oscillates so rapidly that it is imperceptible to human vision.

Abstract: Lenses incorporate freeform power profiles that at least one of slow, retard or preventing myopia progression. An ophthalmic lens includes a first zone at a center of the lens; a first peripheral region continuously extending from the center, the first peripheral region having a different dioptric power than at the center; and a second peripheral region continuously extending from the first peripheral region and having a different dioptric power than the first peripheral region, thereby providing a continuous freeform power profile having substantially equivalent visual performance to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: A method for estimating and tracking refractive error progression of an individual includes estimating a percentile of Spherical Equivalent Refraction (SPHEQ) as a function of at least the individual's age by comparison to a reference population; estimating an expected SPHEQ trajectory over a future predetermined period of time; comparing the expected SPHEQ trajectory with the reference population; and comparing the expected SPHEQ trajectory with an expected SPHEQ trajectory using an ametropia control treatment, thereby showing a possible treatment benefit over the predetermined period of time.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: Lenses are designed using the corneal topography or wavefront measurements of the eye derived by subtracting the optical power of the eye after orthokeratology treatment from the optical power before orthokeratology treatment.

Abstract: Contact lenses incorporate mask lens designs that at least one of slow, retard or preventing myopia progression. The lens includes a first zone at a center of the lens; at least one peripheral zone surrounding the center and having a dioptric power that is different than that at the center; and an opaque mask beginning at a radial distance from the center, thereby providing a lens power profile having substantially equivalent foveal vision correction to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: A lens includes a center of the ophthalmic lens having a negative power that provides foveal vision correction for myopia; a first peripheral zone surrounding the center having a power that gradually increases to a first peak having a dioptric power that is more positive than at the center; and a second peripheral zone surrounding the first peripheral zone and having a second peak having a dioptric power that is more positive than at the center and that is different than the power at the first peak. The power profile slows, retards, or prevents myopia progression independent of pupil size.

Abstract: Contact lenses incorporate mask lens designs that at least one of slow, retard or preventing myopia progression. The lens includes a first zone at a center of the lens; at least one peripheral zone surrounding the center and having a dioptric power that is different than that at the center; and an opaque mask beginning at a radial distance from the center, thereby providing a lens power profile having substantially equivalent foveal vision correction to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Lenses are designed using wavefront measurements amenable to correction factors for near and far vision as well as pupil size to slow or stop myopia progression.

Abstract: Contact lenses incorporating an array of non-coaxial lenslets with add power that create non-coaxial myopic defocus within the optic zone of the lens may be utilized to prevent and/or slow myopia progression. The positive, non-coaxial lenslets cover about twenty to eighty percent of the central pupil area to deliver positive foci of light in front of the retina to slow the rate of myopia progression.

Abstract: Contact lenses incorporate power profiles that minimize visual acuity variation for progressing myopes based upon minimization of the variation of neural sharpness image quality over a specific time period. The contact lens includes a center and at least one peripheral zone surrounding the center and having a different dioptric power than at the center. The lens has power profile selected from the group consisting of a power profile with spherical aberration, a multifocal power profile, a freeform power profile, and a segmented freeform power profile. The power profile is based on an initial paraxial power of a myopia progressor and a defined myopia progression rate over a specific time period, resulting in controlled change of the neural sharpness, thereby minimizing changes in changes in visual acuity at a beginning of the time period and at an end of the time period.

Abstract: Contact lenses incorporate multifocal power profiles that at least one of slow, retard or preventing myopia progression. The lens includes a first zone at a center of the ophthalmic lens and at least one peripheral zone surrounding the first zone. The at least one peripheral zone has a different width and dioptric power than the first zone. The first zone and at least one peripheral zone are stepped or discontinuous. The multifocal power profile has substantially equivalent foveal vision correction to a single vision lens and has a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Lenses incorporate freeform power profiles that at least one of slow, retard or preventing myopia progression. An ophthalmic lens includes a first zone at a center of the lens; a first peripheral region continuously extending from the center, the first peripheral region having a different dioptric power than at the center; and a second peripheral region continuously extending from the first peripheral region and having a different dioptric power than the first peripheral region, thereby providing a continuous freeform power profile having substantially equivalent visual performance to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Contact lenses incorporate mask lens designs that at least one of slow, retard or preventing myopia progression. The lens includes a first zone at a center of the lens; at least one peripheral zone surrounding the center and having a dioptric power that is different than that at the center; and an opaque mask beginning at a radial distance from the center, thereby providing a lens power profile having substantially equivalent foveal vision correction to a single vision lens, and having a depth of focus and reduced retinal image quality sensitivity that slows, retards, or prevents myopia progression.

Abstract: Contact lenses incorporate power profiles that minimize visual acuity variation for progressing myopes based upon minimization of the variation of neural sharpness image quality over a specific time period. The contact lens includes a center and at least one peripheral zone surrounding the center and having a different dioptric power than at the center. The lens has power profile selected from the group consisting of a power profile with spherical aberration, a multifocal power profile, a freeform power profile, and a segmented freeform power profile. The power profile is based on an initial paraxial power of a myopia progressor and a defined myopia progression rate over a specific time period, resulting in controlled change of the neural sharpness, thereby minimizing changes in changes in visual acuity at a beginning of the time period and at an end of the time period.

Abstract: Contact lenses incorporate high plus or add power profiles that at least one of slow, retard or preventing myopia progression and minimize halo effect. The lens includes a center zone with a negative power for myopic vision correction; and at least one treatment zone surrounding the center zone, the at least one treatment zone having a power profile that increases from an outer margin of the center zone to a positive power within the at least one treatment zone of greater than +5.00 D.

Abstract: A lens includes a center of the ophthalmic lens having a negative power that provides foveal vision correction for myopia; a first peripheral zone surrounding the center having a power that gradually increases to a first peak having a dioptric power that is more positive than at the center; and a second peripheral zone surrounding the first peripheral zone and having a second peak having a dioptric power that is more positive than at the center and that is different than the power at the first peak. The power profile slows, retards, or prevents myopia progression independent of pupil size.