Abstract: An intraocular drainage device may include a monolithic silicone body having a flap, a rigid bottom plate having a portion configured to contact a corresponding portion of the flap, and a tube having a proximal end disposed between the flap and the rigid bottom plate. The corresponding portion of the flap may be configured to separate from the portion of the rigid bottom plate responsive to a fluid pressure in aqueous humor received from the tube. A plurality of parallel microgrooves may be formed on one or more portions of one or more outer surfaces of the intraocular drainage device.

Abstract: A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.

Abstract: An intraocular drainage device may include a monolithic silicone body having a flap, a rigid bottom plate having a portion configured to contact a corresponding portion of the flap, and a tube having a proximal end disposed between the flap and the rigid bottom plate. The corresponding portion of the flap may be configured to separate from the portion of the rigid bottom plate responsive to a fluid pressure in aqueous humor received from the tube. A plurality of parallel microgrooves may be formed on one or more portions of one or more outer surfaces of the intraocular drainage device.

Abstract: An intraocular drainage device may include a monolithic silicone body having a flap, a rigid bottom plate having a portion configured to contact a corresponding portion of the flap, and a tube having a proximal end disposed between the flap and the rigid bottom plate. The corresponding portion of the flap may be configured to separate from the portion of the rigid bottom plate responsive to a fluid pressure in aqueous humor received from the tube. A plurality of parallel microgrooves may be formed on one or more portions of one or more outer surfaces of the intraocular drainage device.

Abstract: The present invention relates to an ophthalmic knife and methods of its use for treatment of various conditions including eye diseases, such as glaucoma, using minimally invasive surgical techniques. The invention relates to a multi-blade device for cutting the tissues within the eye, for example, a trabecular meshwork (TM).

Abstract: A nebulizer dispenser has a T-piece, a body sealingly coupled to the T-piece and configured to contain a liquid medication, and a breathing piece sealingly coupled to the T-piece. The dispenser also has a ball-and-socket joint coupled between the T-piece and either the breathing piece or the body. The ball-and-socket joint allows relative rotational motion of the T-piece in a pitch axis, a yaw axis, and a roll axis.

Abstract: A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.

Abstract: A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.

Abstract: A nasal continuous positive airway pressure device for lowering patient work-of-breathing is described. The device may include an inspiratory tubing in fluid communication with at least two nasal prongs; expiratory tubing; and a generator body coupled there between. The generator body may include at least two jets configured for receiving gas from the inspiratory tubing; and a flow enhancer configured for directing received gas. The flow enhancer may include a gas manager configured for channeling received gas towards a jet impingement point via at least two jet paths; a fluidic flip trigger configured for triggering a fluidic flip of channeled gas back towards the expiratory tubing by directing a first portion of exhaled patient breath towards the jet impingement point along a first pathway; and an isolated pathway manager configured for directing a second portion of the exhaled patient breath along a second pathway towards the expiratory tubing.

Abstract: A nebulizer dispenser has a T-piece, a body sealingly coupled to the T-piece and configured to contain a liquid medication, and a breathing piece sealingly coupled to the T-piece. The dispenser also has a ball-and-socket joint coupled between the T-piece and either the breathing piece or the body. The ball-and-socket joint allows relative rotational motion of the T-piece in a pitch axis, a yaw axis, and a roll axis.

Abstract: A method for reducing a loss of medication from a nebulizer includes the steps of entraining a liquid medication into a first flow of a pressurized gas into a nebulizer chamber and also entraining an additional amount of the liquid medication into a second flow of ambient air drawn into the nebulizer chamber through an opening when a patient inhales through the nebulizer chamber. When the patient exhales, a portion of the exhaled breath is directed into the outlet of the nebulizer chamber, thereby increasing a backpressure within the outlet and substantially stopping the second flow of ambient air into the nebulizer chamber, thereby decreasing the amount of medication lost to the ambient environment while the patient is not inhaling.

Abstract: A nebulizer comprises a body, a patient interface, an air inlet, an air outlet, and at least one breathing incentive. The air inlet is coupled with the body and configured for admittance of ambient air into the body in response to inhalation through the patient interface. The air outlet is coupled with the body and configured for discharging exhaled breath. The at least one breathing incentive is integrated with the nebulizer and configured to provide feedback in response to the inhalation. The feedback describes a propriety of a flow rate of the inhalation so as to assist a patient using the nebulizer in achieving a therapeutically effective flow rate for delivery of a medical aerosol.

Abstract: An nCPAP device for assisting patient breathing includes a generator body forming an inlet, a chamber, and first and second flow circuits. The chamber directs pressurized gas from the inlet to the flow circuits. The flow circuits each include a first and second jets, a flow director and an exhaust conduit. The jets emit a jetstream into the flow director in a direction of a patient side thereof. In some embodiments, the flow director forms a first tapered wall section directing inhaled air toward the patient and a second tapered wall section directing exhaled air toward the exhaust conduit. The generator body requires reduced driving pressures to achieve target CPAP levels and reduces total imposed WOB as compared to conventional designs.

Abstract: An nCPAP device for assisting patient breathing includes a generator body forming an inlet, a chamber, and first and second flow circuits. The chamber directs pressurized gas from the inlet to the flow circuits. The flow circuits each include a first and second jets, a flow director and an exhaust conduit. The jets emit a jetstream into the flow director in a direction of a patient side thereof. In some embodiments, the flow director forms a first tapered wall section directing inhaled air toward the patient and a second tapered wall section directing exhaled air toward the exhaust conduit. The generator body requires reduced driving pressures to achieve target CPAP levels and reduces total imposed WOB as compared to conventional designs.

Abstract: A nasal continuous positive airway pressure device for lowering patient work-of-breathing comprising: an inspiratory tubing in fluid communication with at least two nasal prongs; expiratory tubing; and a generator body coupled there between, the generator body comprising: at least two jets configured for receiving gas from the inspiratory tubing; and a flow enhancer configured for directing received gas, the flow enhancer comprising: a gas manager configured for channeling received gas towards a jet impingement point via at least two jet paths; a fluidic flip trigger configured for triggering a fluidic flip of channeled gas back towards the expiratory tubing by directing a first portion of exhaled patient breath towards the jet impingement point along a first pathway; and an isolated pathway manager configured for directing a second portion of the exhaled patient breath along a second pathway towards the expiratory tubing, the second pathway isolated from the first pathway.