Patents by Inventor Khalil N. Bitar

Khalil N. Bitar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Three dimensional bioengineered smooth muscle tissue and sphincters and methods therefor
    Patent number: 7368279
    Abstract: This invention relates to a three dimensional bioengineered sphincter such as a bioengineered internal anal sphincter (IAS) and three-dimensional physiological models of smooth muscle cells. The invention also related to methods for generating a bioengineered sphincter and smooth muscle rings in culture. In addition, the invention provides for methods of using a bioengineered sphincter or bioengineered smooth muscle ring to identify agents that modify contractile force and relaxation in smooth muscle cells.
    Type: Grant
    Filed: November 23, 2005
    Date of Patent: May 6, 2008
    Assignee: The Regents of The University of Michigan
    Inventors: Khalil N. Bitar, Louise Hecker, Keith Baar, Sita Somara