Patents by Inventor Khoi Le
Khoi Le has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11958734Abstract: The invention concerns a bottle opener (101) for removing a cap (301) from a bottle (300). It comprises an image sensor (206) for capturing an image of the cap (301), a fulcrum surface (103) for contacting the cap and a hook (102,104) engageable under a flange (304) of the cap (301) for removing it from the bottle in response of a relative rotation of said bottle opener (101) with respect to the bottle (300) using the fulcrum surface (103) as a fulcrum. A removal detector (202, 204) is arranged to trigger a capture of an image by sensing a force between the fulcrum surface (103) and the hook (104) that exceeds a predefined threshold.Type: GrantFiled: June 12, 2018Date of Patent: April 16, 2024Assignee: WeCheer SAInventors: Karim Choueiri, Khoi Quc Anh Luong, Aurèle De Bosset, Minh Ly, Tai Le Tan Huynh
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Patent number: 11890213Abstract: Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.Type: GrantFiled: November 18, 2020Date of Patent: February 6, 2024Assignee: ZENFLOW, INC.Inventors: Austin Michael Bly, Cesar Abalos Ico, Shreya Mehta, William Martin Belef, Samuel Allen Scaglione, Marcel Song Sicotte, Khoi Le
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Publication number: 20230200992Abstract: A delivery device for an implantable medical device having a retention member at an end thereof may include a shaft extending in a longitudinal direction and defining a longitudinal axis, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and an energy storage element positioned on the longitudinal portion of the shaft and configured to be radially compressed by the medical device when the elongated sheath covers the compartment containing the medical device. The sheath may be slidable relative to the shaft in the longitudinal direction. The retainer may include a recess adapted to receive the retention member of the medical device in the assembled condition.Type: ApplicationFiled: February 23, 2023Publication date: June 29, 2023Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Valerie J. Glazier, Ralph Joseph Thomas, Khoi Le
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Patent number: 11612483Abstract: A delivery device for an implantable medical device having a retention member at an end thereof may include a shaft extending in a longitudinal direction and defining a longitudinal axis, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and an energy storage element positioned on the longitudinal portion of the shaft and configured to be radially compressed by the medical device when the elongated sheath covers the compartment containing the medical device. The sheath may be slidable relative to the shaft in the longitudinal direction. The retainer may include a recess adapted to receive the retention member of the medical device in the assembled condition.Type: GrantFiled: April 28, 2021Date of Patent: March 28, 2023Assignee: St. Jude Medical, Cardiology Division, Ine.Inventors: Valerie J. Glazier, Ralph Joseph Thomas, Khoi Le
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Patent number: 11523902Abstract: Apparatus and methods are described herein for use in the delivery and deployment of a prosthetic mitral valve into a heart. In some embodiments, an apparatus includes a catheter assembly, a valve holding tube and a handle assembly. The valve holding tube is releasably couplable to a proximal end portion of the catheter assembly and to a distal end portion of the handle assembly. The handle assembly includes a housing and a delivery rod. The delivery rod is configured to be actuated to move distally relative to the housing to move a prosthetic heart valve disposed within the valve holding tube out of the valve holding tube and distally within a lumen of the elongate sheath of the catheter assembly. The catheter assembly is configured to be actuated to move proximally relative to the housing such that the prosthetic valve is disposed outside of the lumen of the elongate sheath.Type: GrantFiled: April 23, 2020Date of Patent: December 13, 2022Assignee: Tendyne Holdings, Inc.Inventors: Craig A. Ekvall, Khoi Le, John F. Otte, Zachary J. Tegels, Robert M. Vidlund
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Publication number: 20220378287Abstract: Disclosed herein are endoscope assemblies, and more particularly endoscopes with a working channel for use in hysteroscopy, and methods of use thereof. Devices and systems related to an integrated hysteroscopic treatment system including an endoscopic viewing system, a fluid management system, a resecting device and a controller for operating all the systems. Also disclosed are integrated hysteroscopic treatment systems that include an endoscopic viewing system, a fluid management system, a resecting device and a controller for operating all the systems.Type: ApplicationFiled: July 29, 2022Publication date: December 1, 2022Applicant: Meditrina, Inc.Inventors: Csaba TRUCKAI, Britta NELSON, Nicholas LANDGRAF, Daniel TRUCKAI, Roy MORGAN, Khoi LE
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Patent number: 11432717Abstract: Disclosed herein are endoscope assemblies, and more particularly endoscopes with a working channel for use in hysteroscopy, and methods of use thereof. Devices and systems related to an integrated hysteroscopic treatment system including an endoscopic viewing system, a fluid management system, a resecting device and a controller for operating all the systems. Also disclosed are integrated hysteroscopic treatment systems that include an endoscopic viewing system, a fluid management system, a resecting device and a controller for operating all the systems.Type: GrantFiled: October 11, 2018Date of Patent: September 6, 2022Assignee: Meditrina, Inc.Inventors: Csaba Truckai, Britta Nelson, Nicholas Landgraf, Daniel Truckai, Roy Morgan, Khoi Le
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Patent number: 11327075Abstract: It was discovered that hydrogel scaffolds can be used to induce phase separation as aqueous two-phase systems (ATPSs) pass through and/or rehydrate the scaffolds, allowing for concentration of target analyte(s) (e.g., biomolecule(s)) into a particular phase of the ATPS or into a leading front. Accordingly, in various embodiments methods and devices are provided that utilize aqueous two-phase systems and hydrogel scaffolds to improve the sensitivity of assays (e.g., of point-of-care assays) without sacrificing cost or ease of use.Type: GrantFiled: August 21, 2017Date of Patent: May 10, 2022Assignee: The Regents of the University of CaliforniaInventors: Daniel Takashi Kamei, Benjamin Ming Wu, David Yuan Pereira, Chloe Michelle Wu, Matthew Foosing Yee, Joshua Anthony Keefe, Christina Caroline Pearce, Amir Adam Dailamy, Vincent K. Wong, Nguyen Khoi Le
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Publication number: 20220133329Abstract: A vascular occlusion system may include a microcatheter configured to navigate a vasculature, an elongate shaft slidably disposed within a lumen of the microcatheter, the elongate shaft having a lumen extending from a proximal end of the elongate shaft to a distal end of the elongate shaft, a plurality of occlusive medical devices releasably connected to the elongate shaft, and a release wire slidably disposed within the elongate shaft and at least a portion of each of the plurality of occlusive medical devices. The release wire secures each of the plurality of occlusive medical devices to the distal end of the elongate shaft when the release wire is disposed within at least a portion of each of the plurality of occlusive medical devices.Type: ApplicationFiled: January 19, 2022Publication date: May 5, 2022Applicant: BOSTON SCIENTIFIC SCIMED, INC.Inventors: Nicholas Lee Tassoni, Khoi Le, Jeffry D. Johnson
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Patent number: 11295112Abstract: Embodiments discussed herein facilitate training deep learning models to generate synthetic versions of histological texture features and employing such deep learning models. One example embodiment is an apparatus configured to convert a stained histological image to grayscale; extract patches from the grayscale image; for each patch of the plurality of patches: provide that patch to a deep learning model trained to generate a synthetic version of a texture feature; and obtain an associated patch from the deep learning model that indicates an associated value of the synthetic version of the histology texture feature for each pixel of that patch; and merge the associated patches for each patch of the plurality of patches to generate an associated feature map for the stained histological image, wherein the associated feature map indicates the associated value of the synthetic version of the histology texture feature for each pixel of the plurality of pixels.Type: GrantFiled: September 23, 2020Date of Patent: April 5, 2022Assignee: Case Western Reserve UniversityInventors: Cheng Lu, Anant Madabhushi, Khoi Le
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Publication number: 20220071704Abstract: A catheter system (100) for treating a vascular lesion (106) within or adjacent to a heart valve (108) within a body (107) of a patient (109), includes an energy source (124), and a plurality of spaced apart treatment devices (143). The energy source (124) generates energy. Each treatment device (143) includes (i) a balloon (104) that is positionable substantially adjacent to the vascular lesion (106), the balloon (104) having a balloon wall (130) that defines a balloon interior (146), the balloon (104) being configured to retain a balloon fluid (132) within the balloon interior (146); and (ii) at least one of a plurality of energy guides (122A) that receive energy from the energy source (124) so that plasma (134) is formed in the balloon fluid (132) within the balloon interior (146).Type: ApplicationFiled: September 1, 2021Publication date: March 10, 2022Inventor: Khoi Le
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Publication number: 20220015620Abstract: Endoscopes include a shaft having a diameter extending about a longitudinal axis to a distal housing. An image sensor is carried by the distal housing, and a channel extends through the shaft and distal housing. A distal portion of the channel is adjustable or curved to accommodate introduction of a tool while maintaining a reduced shaft diameter. In some embodiments, a diagonal dimension of the image sensor when combined with a channel diameter is greater than a shaft diameter. In some embodiments, the distal housing is flexible to accommodate passage of a straight tool through a curved distal portion of a working channel. In some embodiments, a curved distal portion of a working channel may be reoriented to deflect a flexible tool.Type: ApplicationFiled: September 30, 2021Publication date: January 20, 2022Applicant: Meditrina, Inc.Inventors: Csaba Truckai, Daniel Truckai, Khoi Le, Kevin Moss, Britta Nelson, Nicholas Landgraf
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Patent number: 11096560Abstract: A disposable cover for use with an endoscope includes an elongated sheath having and having an open proximal end and a closed distal end. A channel extends along a central axis of the sheath from the open proximal end to the closed distal end, and the channel is configured to accommodate insertion of an endoscope. A proximal region of the sheath is formed as a rigid thin-wall sleeve and a distal region of the sheath is formed as a flexible thin-wall sleeve. The flexible thin-wall sleeve is configured to allow deflection of said distal region in cooperation with an articulating distal end of an endoscope.Type: GrantFiled: September 22, 2017Date of Patent: August 24, 2021Assignee: Meditrina, Inc.Inventors: Csaba Truckai, Daniel Truckai, Khoi Le, Kevin Moss, Nicholas Landgraf, Britta Nelson
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Publication number: 20210244537Abstract: A delivery device for an implantable medical device having a retention member at an end thereof may include a shaft extending in a longitudinal direction and defining a longitudinal axis, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and an energy storage element positioned on the longitudinal portion of the shaft and configured to be radially compressed by the medical device when the elongated sheath covers the compartment containing the medical device. The sheath may be slidable relative to the shaft in the longitudinal direction. The retainer may include a recess adapted to receive the retention member of the medical device in the assembled condition.Type: ApplicationFiled: April 28, 2021Publication date: August 12, 2021Applicant: St. Jude Medical, Cardiology Division, Inc.Inventors: Valerie J. Glazier, Ralph Joseph Thomas, Khoi Le
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Patent number: 11026789Abstract: A delivery device for an implantable medical device having a retention member at an end thereof may include a shaft extending in a longitudinal direction and defining a longitudinal axis, an elongated sheath surrounding a longitudinal portion of the shaft, a compartment defined inside the sheath and adapted to receive the medical device in an assembled condition, a retainer positioned at one end of the compartment, and an energy storage element positioned on the longitudinal portion of the shaft and configured to be radially compressed by the medical device when the elongated sheath covers the compartment containing the medical device. The sheath may be slidable relative to the shaft in the longitudinal direction. The retainer may include a recess adapted to receive the retention member of the medical device in the assembled condition.Type: GrantFiled: March 14, 2018Date of Patent: June 8, 2021Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Valerie J. Glazier, Ralph Joseph Thomas, Khoi A. Le
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Publication number: 20210145619Abstract: Systems, devices, and methods are provided for the delivery of an implant into the prostatic urethra. Embodiments of delivery systems can include a delivery device for insertion into the patient and a proximal control device for use in controlling release of the implant from the delivery device.Type: ApplicationFiled: November 18, 2020Publication date: May 20, 2021Inventors: Austin Michael Bly, Cesar Abalos Ico, Shreya Mehta, William Martin Belef, Samuel Allen Scaglione, Marcel Song Sicotte, Khoi Le
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Patent number: 11000287Abstract: An occlusive medical device system may include an elongate shaft having a lumen extending longitudinally through a tubular body portion and a plurality of retaining arms extending distally from the tubular body portion. An occlusive medical device may include a proximal tubular mounting portion fixed to an expandable occlusive element. A release wire may be axially translatable between a distal engagement position and a proximal released position, the release wire having a distal engagement portion and a distal retention portion distal of the distal engagement portion. The distal engagement portion may be configured to engage the plurality of retaining arms in the distal engagement position, thereby urging the plurality of retaining arms into releasable engagement with the proximal tubular mounting portion, wherein when the release wire is in the proximal released position, the plurality of retaining arms is deflectable radially inward to disengage from the proximal tubular mounting portion.Type: GrantFiled: August 15, 2018Date of Patent: May 11, 2021Assignee: Boston Scientific Scimed, Inc.Inventors: Nicholas Lee Tassoni, Khoi Le
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Publication number: 20210089745Abstract: Embodiments discussed herein facilitate training deep learning models to generate synthetic versions of histological texture features and employing such deep learning models. One example embodiment is an apparatus configured to convert a stained histological image to grayscale; extract patches from the grayscale image; for each patch of the plurality of patches: provide that patch to a deep learning model trained to generate a synthetic version of a texture feature; and obtain an associated patch from the deep learning model that indicates an associated value of the synthetic version of the histology texture feature for each pixel of that patch; and merge the associated patches for each patch of the plurality of patches to generate an associated feature map for the stained histological image, wherein the associated feature map indicates the associated value of the synthetic version of the histology texture feature for each pixel of the plurality of pixels.Type: ApplicationFiled: September 23, 2020Publication date: March 25, 2021Inventors: Cheng Lu, Anant Madabhushi, Khoi Le
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Patent number: 10946310Abstract: An alternating flow column chromatography apparatus comprising a ‘U’ shaped or T shaped separation column including at least one loading port for loading of components for separation, a first purification column in fluid communication with one end of the separation column and a second purification column in fluid communication with another end of the separation column, at least one eluent input port, an eluate output port and an alternating flow valve in fluid communication with the primary eluent input port, the eluate output port, the first purification column and the second purification column wherein, when operated, the alternating flow valve reverses the flow of eluent through the purification columns and the separation column. Also a method of using the apparatus. A benefit of the apparatus and method is more efficient operation compared to existing direct flow column chromatography apparatuses.Type: GrantFiled: January 11, 2018Date of Patent: March 16, 2021Inventors: Van So Le, Minh Khoi Le
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Patent number: 10758351Abstract: A delivery device for a collapsible prosthetic heart valve includes an operating handle and a catheter assembly. The operating handle may include a housing defining a movement space therein, a carriage assembly moveable in a longitudinal direction within the movement space, a deployment actuator coupled to the housing and rotatable relative to the housing, and a coupling assembly rotationally fixed to the deployment actuator. The catheter assembly may include a first shaft around which a compartment is defined and a distal sheath operatively connected to the carriage assembly. Movement of the carriage assembly in the longitudinal direction in the movement space may move the distal sheath between the closed condition and the open condition. The coupling assembly may have an engaged position in which rotation of the deployment actuator moves the carriage assembly, and a disengaged position in which rotation of the deployment actuator does not move the carriage assembly.Type: GrantFiled: November 28, 2017Date of Patent: September 1, 2020Assignee: St. Jude Medical, Cardiology Division, Inc.Inventors: Benjamin E. Morris, Eric E. Bielefeld, Gregory R. Furnish, Ralph Joseph Thomas, Khoi A. Le, Bradley Charles Knippel, Valerie J. Glazier